June 10th, 2013
•MicroRNAs have significant roles in brain structure and function. Here we describe a method to enforce hippocampal miRNA over-expression using stereotactic injection of an engineered miRNA-expressing lentivirus. This approach can serve as a relatively rapid way to assess the in vivo effects of over-expressed miRNAs in specific brain regions.
Related Videos
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
Behavioral Assessment of the Aging Mouse Vestibular System
Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
Experimental Assessment of Mouse Sociability Using an Automated Image Processing Approach
Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning
The Rodent Psychomotor Vigilance Test (rPVT): A Method for Assessing Neurobehavioral Performance in Rats and Mice
Behavioral Assessment of Hearing in 2 to 4 Year-old Children: A Two-interval, Observer-based Procedure Using Conditioned Play-based Responses
Measuring Active and Passive Tameness Separately in Mice
A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice
Copyright © 2024 MyJoVE Corporation. 판권 소유