Preparation of Medial Thalamus-anterior Cingulate Cortex Brain Slice
3:01
Preparation of Perfusion Chamber for Multielectrode Array Recording and Electric Field Generation
4:23
Electrically-induced Cortical Synaptic Responses and Seizure-like Activity
5:58
Testing Effect of DCS on Evoked Cortical Responses
7:37
Results: Testing of Evoked Responses and Effect of DCS on Seizure Activity
8:37
Conclusion
필기록
The overall goal of this experimental procedure, is to access the arrangement of electrodes in the recording chamber for direct current stimulation of a brain slice and it's effect on seizure-like activity recorded with a multi-electrode array. Th
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Studies have shown that cathodal transcranial direct-current stimulation can produce suppressive effects on drug-resistant seizures. In this study, an in vitro experimental setup was devised in which the direct-current stimulation and multielectrode array recording of seizure-like activity were evaluated in mice brain slice preparation. The direct-current stimulation parameters were evaluated.