Intrasplenic Transplantation of Human Hepatic Stem Cells
6:25
Detection of Transplanted Human Hepatic Stem Cell-derived Hepatocytes in the Mouse Liver
8:13
Results: Humanization of Mouse Livers using Human Hepatic Stem Cells
10:09
Conclusion
필기록
The overall goal of this surgical stem cell transplant procedure is to generate a novel chimeric mouse model with human liver function using human immature hepatic stem progenitor cells that allow cell proliferation, maturation and differentiation
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Here, we present a novel humanized mouse liver model generated in Alb-toxin receptor mediated cell knockout (TRECK)/SCID mice following the transplantation of immature and expandable human hepatic stem cells.