March 7th, 2019
•Molecular imaging with matrix-assisted laser desorption/ionization-based imaging mass spectrometry (MALDI-IMS) allows the simultaneous mapping of multiple analytes in biological samples. Here, we present a protocol for the detection and visualization of amyloid β protein on brain tissues of Alzheimer's disease and cerebral amyloid angiopathy samples using MALDI-IMS.
Related Videos
Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
Time-lapse Live Imaging of Clonally Related Neural Progenitor Cells in the Developing Zebrafish Forebrain
A Rapid Approach to High-Resolution Fluorescence Imaging in Semi-Thick Brain Slices
Visualization of Proprioceptors in Drosophila Larvae and Pupae
Optogenetic Perturbation of Neural Activity with Laser Illumination in Semi-intact Drosophila Larvae in Motion
Deep Brain Stimulation with Simultaneous fMRI in Rodents
Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
Sublimation of DAN Matrix for the Detection and Visualization of Gangliosides in Rat Brain Tissue for MALDI Imaging Mass Spectrometry
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin
Copyright © 2024 MyJoVE Corporation. 판권 소유