Development of Recombinant Proteins to Treat Chronic Pain
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9.4K Views
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10:37 min
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April 11th, 2018
DOI :
April 11th, 2018
•Judith Prado1, Jelena Popov-Celeketic2, Cristine Steen-Louws1, Ramin Raoof1, Eric Hack1, Niels Eijkelkamp1,3
1Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, 2Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht University
Rozdziały w tym wideo
0:05
Title
1:15
Cell Transfection, Protein Purification, and Affinity Chromatrography
3:49
Bioactivity of IL4-10 Fusion Protein
4:46
Induction of Chronic Inflammatory Pain in Mice. Pain Measurements: The Von Frey Test: Mechanical Sensitivity
5:52
Pain measurements: Hargreaves Test for Thermal Sensitivity Dynamic Weight Bearing Test for Postural Deficits
6:48
Intrathecal Injection of IL4-10 Fusion Protein for Analgesia
7:56
Results: Persistent Inflammatory Pain Reduction Using IL4-10 Fusion Protein
9:38
Conclusion
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