Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

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2.8K Views

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05:00 min

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March 3rd, 2021

DOI :

10.3791/62325-v

March 3rd, 2021

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Daniel Omileke¹, Steven Bothwell¹, Daniel J. Beard¹, Nikolce Mackovski¹, Sara Azarpeykan¹, Kirsten Coupland¹, Adjanie Patabendige¹, Neil Spratt¹^,²

¹School of Biomedical Sciences and Pharmacy, University of Newcastle, ²Department of Neurology, John Hunter Hospital, Hunter New England Local Health District

Podsumowanie

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Hypothermia Induction

Gradual Cooling Protocol

Clinical Relevance

Preclinical Investigation

Temperature Monitoring

Over Cooling Management

Rozdziały w tym wideo

0:04

Introduction

0:45

Datalogger Implantation

1:44

Induction of Active (Fast) Hypothermia

3:07

Induction of Clinically Achievable Gradual Onset Hypothermia

3:49

Results: Wistar Rat Responses to Induced Hypothermia

4:33

Conclusion

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