Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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09:36 min
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December 22nd, 2023
DOI :
December 22nd, 2023
•Yangpeng Li*1,2, Jun Yang*1, Rui Zhang1, Tangting Chen1, Shiyu Zhang1, Yuqing Zheng1, Qiang Wen3, Tao Li1, Xiaoqiu Tan1,2, Ming Lei1,4, Xianhong Ou1
1Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University, 2Department of Cardiology, the Affiliated Hospital of Southwest Medical University, 3Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 4Department of Pharmacology, University of Oxford
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Rozdziały w tym wideo
0:04
Introduction
1:00
Mouse Heart Harvest, Cannulation, and Perfusion
3:14
Optical Mapping and Arrhythmia Induction
6:38
Results: APD80 and CaTD80 Analysis at 10 Hz Before and After ISO Challenge
8:36
Conclusion
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