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The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS)

3.1K Views

07:22 min

January 12th, 2024

DOI :

10.3791/65718-v

January 12th, 2024


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Biophysical Assays

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0:00

Introduction

1:08

Isothermal Titration Calorimetry for Evaluating PROTACS‐Induced Ternary Complex Formation

2:23

Biolayer Interferometry (BLI) for Evaluating PROTACS‐Induced Ternary Complex Formation

3:45

Surface Plasmon Resonance (SPR) for Evaluating PROTACS‐Induced Ternary Complex Formation

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