Cardiovascular Division,
Department of Medicine,
Cardiac Muscle Research Laboratory,
Cardiovascular Division, Department of Medicine,
Cardiac Muscle Research Laboratory, Cardiovascular Division
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Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart.
The Journal of biological chemistry Jun, 2002 | Pubmed ID: 11943770
Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure.
Circulation Aug, 2002 | Pubmed ID: 12196344
Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice.
Circulation Oct, 2002 | Pubmed ID: 12379584
Influence of gender on the response to hemodynamic overload after myocardial infarction.
American journal of physiology. Heart and circulatory physiology Dec, 2002 | Pubmed ID: 12388328
Titin determines the Frank-Starling relation in early diastole.
The Journal of general physiology Feb, 2003 | Pubmed ID: 12566538
Mg-ATPase and Ca+ activated myosin AtPase activity in ventricular myofibrils from non-failing and diseased human hearts--effects of calcium sensitizing agents MCI-154, DPI 201-106, and caffeine.
Molecular and cellular biochemistry Mar, 2003 | Pubmed ID: 12708747
Deletion of cytosolic phospholipase A2 promotes striated muscle growth.
Nature medicine Jul, 2003 | Pubmed ID: 12808451
Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes.
Circulation research Jul, 2003 | Pubmed ID: 12829617
Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta.
American journal of physiology. Cell physiology Feb, 2004 | Pubmed ID: 14522821
Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14676206
Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.
Circulation Feb, 2004 | Pubmed ID: 14757696
Pressure overload-induced myocardial hypertrophy in mice does not require gp91phox.
Circulation Mar, 2004 | Pubmed ID: 14981002
Glycogen synthase kinase-3beta regulates growth, calcium homeostasis, and diastolic function in the heart.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15020584
Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress.
Circulation research Apr, 2004 | Pubmed ID: 15044325
Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes.
Circulation Jun, 2004 | Pubmed ID: 15173024
Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling.
The Journal of biological chemistry Dec, 2004 | Pubmed ID: 15385548
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload.
Circulation Feb, 2005 | Pubmed ID: 15687129
Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy.
Journal of molecular and cellular cardiology Feb, 2005 | Pubmed ID: 15698844
Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras.
Circulation Mar, 2005 | Pubmed ID: 15723974
Mesenchymal stem cells in the infarcted heart.
Coronary artery disease Mar, 2005 | Pubmed ID: 15735401
Genetic determinants of vascular oxidant stress and endothelial dysfunction.
Congestive heart failure (Greenwich, Conn.) Mar-Apr, 2005 | Pubmed ID: 15860972
Yin and Yang of myocardial transforming growth factor-beta1: timing is everything.
Circulation May, 2005 | Pubmed ID: 15897356
CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation.
Circulation research Jul, 2005 | Pubmed ID: 15947249
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure.
The Journal of clinical investigation Aug, 2005 | Pubmed ID: 16075055
Restoration of cardiac progenitor cells after myocardial infarction by self-proliferation and selective homing of bone marrow-derived stem cells.
Circulation research Nov, 2005 | Pubmed ID: 16269652
Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy.
The Journal of biological chemistry Mar, 2006 | Pubmed ID: 16380388
Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2006 | Pubmed ID: 16469952
Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4.
American journal of physiology. Heart and circulatory physiology May, 2006 | Pubmed ID: 16603706
The beta-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy.
Molecular and cellular biology Jun, 2006 | Pubmed ID: 16738313
PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractility.
Circulation research Aug, 2006 | Pubmed ID: 16809552
A novel microfluidic impedance assay for monitoring endothelin-induced cardiomyocyte hypertrophy.
Biosensors & bioelectronics Mar, 2007 | Pubmed ID: 16962309
Collagen-GAG scaffolds grafted onto myocardial infarcts in a rat model: a delivery vehicle for mesenchymal stem cells.
Tissue engineering Sep, 2006 | Pubmed ID: 16995780
Delayed erythropoietin therapy reduces post-MI cardiac remodeling only at a dose that mobilizes endothelial progenitor cells.
American journal of physiology. Heart and circulatory physiology Jan, 2007 | Pubmed ID: 16997893
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 prevents myocardial dysfunction in murine models of septic shock.
Circulation research Jan, 2007 | Pubmed ID: 17138944
Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.
Molecular and cellular biology Mar, 2007 | Pubmed ID: 17189427
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity.
Nature medicine Feb, 2007 | Pubmed ID: 17273168
Peroxisome proliferator-activated receptor alpha-independent actions of fenofibrate exacerbates left ventricular dilation and fibrosis in chronic pressure overload.
Hypertension May, 2007 | Pubmed ID: 17353509
Cell therapy in heart failure.
Heart failure clinics Jul, 2005 | Pubmed ID: 17386854
Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2007 | Pubmed ID: 17438289
Adult stem cells and heart regeneration.
Expert review of cardiovascular therapy May, 2007 | Pubmed ID: 17489674
Simultaneous orientation and cellular force measurements in adult cardiac myocytes using three-dimensional polymeric microstructures.
Cell motility and the cytoskeleton Sep, 2007 | Pubmed ID: 17615571
The bone marrow--cardiac axis of myocardial regeneration.
Progress in cardiovascular diseases Jul-Aug, 2007 | Pubmed ID: 17631435
Long-term effects of increased glucose entry on mouse hearts during normal aging and ischemic stress.
Circulation Aug, 2007 | Pubmed ID: 17679614
Not all hypertrophy is created equal.
Circulation research Nov, 2007 | Pubmed ID: 18040021
Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.
The Journal of clinical investigation Jan, 2008 | Pubmed ID: 18060044
Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G alpha o* protein.
American journal of physiology. Heart and circulatory physiology Mar, 2008 | Pubmed ID: 18192223
A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility.
Biophysical journal May, 2008 | Pubmed ID: 18212018
Real-time monitoring primary cardiomyocyte adhesion based on electrochemical impedance spectroscopy and electrical cell-substrate impedance sensing.
Analytical chemistry Feb, 2008 | Pubmed ID: 18215019
Isolation, culture, and functional analysis of adult mouse cardiomyocytes.
Methods in molecular medicine , 2007 | Pubmed ID: 18287677
Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.
Circulation Mar, 2008 | Pubmed ID: 18316486
Pump to survive: novel cytoprotective strategies for cardiac progenitor cells.
Circulation research May, 2008 | Pubmed ID: 18467637
Evolving cell-based therapies for heart failure patients.
Current treatment options in cardiovascular medicine Aug, 2008 | Pubmed ID: 18647591
Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells.
Circulation research Oct, 2008 | Pubmed ID: 18787193
Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice.
Circulation Jan, 2009 | Pubmed ID: 19118250
Impedance-based monitoring of ongoing cardiomyocyte death induced by tumor necrosis factor-alpha.
Biophysical journal Mar, 2009 | Pubmed ID: 19254558
A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure.
Circulation Apr, 2009 | Pubmed ID: 19349318
Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.
Circulation research Jul, 2009 | Pubmed ID: 19423844
Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity.
Circulation Jun, 2009 | Pubmed ID: 19451348
Intervention of cardiomyocyte death based on real-time monitoring of cell adhesion through impedance sensing.
Biosensors & bioelectronics Sep, 2009 | Pubmed ID: 19615884
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure.
Circulation research Sep, 2009 | Pubmed ID: 19679836
A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo.
Molecular and cellular biology Nov, 2009 | Pubmed ID: 19720742
Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart.
American journal of physiology. Heart and circulatory physiology Nov, 2009 | Pubmed ID: 19734360
Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms.
American journal of physiology. Heart and circulatory physiology Dec, 2009 | Pubmed ID: 19801492
Intervention of cardiomyocyte death based on the impedance-sensing technique of monitoring cell adhesion.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2009 | Pubmed ID: 19964632
CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload through selective repression and activation of specific transcriptional pathways.
Omics : a journal of integrative biology Dec, 2009 | Pubmed ID: 20001863
Effects of trimetazidine, a partial inhibitor of fatty acid oxidation, on ventricular function and survival after myocardial infarction and reperfusion in the rat.
Fundamental & clinical pharmacology Aug, 2010 | Pubmed ID: 20030737
Redox-mediated reciprocal regulation of SERCA and Na+-Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes.
Free radical biology & medicine May, 2010 | Pubmed ID: 20132882
Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2010 | Pubmed ID: 20150510
Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.
Circulation research Aug, 2010 | Pubmed ID: 20558824
The paradoxical role of inflammation in cardiac repair and regeneration.
Journal of cardiovascular translational research Aug, 2010 | Pubmed ID: 20559773
Isolation of resident cardiac progenitor cells by Hoechst 33342 staining.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20680812
Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Circulation Sep, 2010 | Pubmed ID: 20733101
Preventing cardiac remodeling: the combination of cell-based therapy and cardiac support therapy preserves left ventricular function in rodent model of myocardial ischemia.
The Journal of thoracic and cardiovascular surgery Dec, 2010 | Pubmed ID: 21078426
Telomere dysfunction induces metabolic and mitochondrial compromise.
Nature Feb, 2011 | Pubmed ID: 21307849
Notch1 in bone marrow-derived cells mediates cardiac repair after myocardial infarction.
Circulation Mar, 2011 | Pubmed ID: 21321153
Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice.
Circulation research Apr, 2011 | Pubmed ID: 21372284
Evidence for human lung stem cells.
The New England journal of medicine May, 2011 | Pubmed ID: 21561345
Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium.
Circulation. Cardiovascular imaging Nov, 2011 | Pubmed ID: 21836081
Nanoparticles targeting the infarcted heart.
Nano letters Oct, 2011 | Pubmed ID: 21899318
Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis.
Blood Dec, 2011 | Pubmed ID: 21998211
Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3.
Circulation research Dec, 2011 | Pubmed ID: 22034491
Current perspectives on cardiac amyloidosis.
American journal of physiology. Heart and circulatory physiology Feb, 2012 | Pubmed ID: 22058156
Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress.
Journal of molecular and cellular cardiology Mar, 2012 | Pubmed ID: 22227328
AMPK isoform expression in the normal and failing hearts.
Journal of molecular and cellular cardiology Jan, 2012 | Pubmed ID: 22314372
Cardiac side population cells: moving toward the center stage in cardiac regeneration.
Circulation research May, 2012 | Pubmed ID: 22581921
The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping.
American journal of physiology. Heart and circulatory physiology Jul, 2012 | Pubmed ID: 22636675
Optimized ventricular restraint therapy: adjustable restraint is superior to standard restraint in an ovine model of ischemic cardiomyopathy.
The Journal of thoracic and cardiovascular surgery Mar, 2013 | Pubmed ID: 22698557
Spot identification and quality control in cell-based microarrays.
ACS combinatorial science Aug, 2012 | Pubmed ID: 22850537
Regeneration in heart disease-Is ECM the key?
Life sciences Oct, 2012 | Pubmed ID: 22982346
Abcg2 Regulates Cell Cycle Progression and Asymmetric Division in Mouse Cardiac Side Population Progenitor Cells.
Circulation research Nov, 2012 | Pubmed ID: 23136123
Adult cardiac progenitor cell aggregates exhibit survival benefit both in vitro and in vivo.
PloS one , 2012 | Pubmed ID: 23226295
PGC1α plays a critical role in TWEAK-induced cardiac dysfunction.
PloS one , 2013 | Pubmed ID: 23342071
Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.
Circulation. Cardiovascular imaging May, 2013 | Pubmed ID: 23537953
Regional cardiac dysfunction and dyssynchrony in a murine model of afterload stress.
PloS one , 2013 | Pubmed ID: 23560059
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts.
Circulation research Jun, 2013 | Pubmed ID: 23575307
Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish.
American journal of physiology. Heart and circulatory physiology Jul, 2013 | Pubmed ID: 23624626
Methods to study the proliferation and differentiation of cardiac side population (CSP) cells.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23807790
Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.
Basic research in cardiology Sep, 2013 | Pubmed ID: 23982491
MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling.
Circulation research Nov, 2013 | Pubmed ID: 24047927
Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2013 | Pubmed ID: 24082102
Flt3 activation improves post-myocardial infarction remodeling involving a cytoprotective effect on cardiomyocytes.
Journal of the American College of Cardiology Oct, 2013 | Pubmed ID: 24184252
Gradient static-strain stimulation in a microfluidic chip for 3D cellular alignment.
Lab on a chip Dec, 2013 | Pubmed ID: 24253194
Microfluidics-assisted fabrication of gelatin-silica core-shell microgels for injectable tissue constructs.
Biomacromolecules Jan, 2014 | Pubmed ID: 24344625
Regenerative therapy for cardiovascular disease.
Translational research : the journal of laboratory and clinical medicine Dec, 2013 | Pubmed ID: 24378637
A systematic survey of lipids across mouse tissues.
American journal of physiology. Endocrinology and metabolism Apr, 2014 | Pubmed ID: 24518676
Cardiac stem cells: biology and clinical applications.
Antioxidants & redox signaling Nov, 2014 | Pubmed ID: 24597850
Microstructural impact of ischemia and bone marrow-derived cell therapy revealed with diffusion tensor magnetic resonance imaging tractography of the heart in vivo.
Circulation Apr, 2014 | Pubmed ID: 24619466
Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium.
Circulation research May, 2014 | Pubmed ID: 24625784
Identifying early changes in myocardial microstructure in hypertensive heart disease.
PloS one , 2014 | Pubmed ID: 24831515
Worming along in amyloid cardiotoxicity.
Blood Jun, 2014 | Pubmed ID: 24904094
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity.
EMBO molecular medicine Nov, 2014 | Pubmed ID: 25319546
A role for matrix stiffness in the regulation of cardiac side population cell function.
American journal of physiology. Heart and circulatory physiology Feb, 2015 | Pubmed ID: 25724498
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity.
EMBO molecular medicine May, 2015 | Pubmed ID: 25940533
MicroRNA-34a Plays a Key Role in Cardiac Repair and Regeneration Following Myocardial Infarction.
Circulation research Aug, 2015 | Pubmed ID: 26082557
Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure.
Circulation research Jan, 2019 | Pubmed ID: 30605412
Alteration in ventricular pressure stimulates cardiac repair and remodeling.
Journal of molecular and cellular cardiology 08, 2019 | Pubmed ID: 31220468
Quantitative [F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis.
European journal of nuclear medicine and molecular imaging Dec, 2019 | Pubmed ID: 31807884
Harnessing Cardiac Regeneration as a Potential Therapeutic Strategy for AL Cardiac Amyloidosis.
Current cardiology reports Jan, 2020 | Pubmed ID: 31932992
Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction.
Circulation Mar, 2020 | Pubmed ID: 31948273
Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor protein.
Scientific reports Jan, 2020 | Pubmed ID: 32005965
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