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JoVE Journal

Medicine

This content is Open Access.

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

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06:38 min

March 11th, 2016

March 11th, 2016

11,773 Views

0:05

Title

1:28

Nephrotoxicity Rat Model and Transverse Imaging of Kidney

3:56

Nephrotoxicity Induction using Cisplatin

4:31

Results: Creatinine, Histology and Ultrasound Images after Cisplatin Treatment

5:53

Conclusion

Transcrição

Early stage hemodynamic dysfunction is critical to the development of kidney disease. Yet, detection methodologies are limited. Recent advances in sonography provide a noninvasive, accurate option for early detection of kidney injury. This study outlines a step-by-step, sonographic methodology for detecting kidney dysfunction using a drug-induced nephrotoxicity rat model.

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