Daniel Irimia

Neutrophil migration assay from a drop of blood.

Kinetics and mechanism of intercellular ice propagation in a micropatterned tissue construct.

Parametric analysis of intercellular ice propagation during cryosurgery, simulated using monte carlo techniques.

Kinetics of intracellular ice formation in one-dimensional arrays of interacting biological cells.

Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device.

Blood-on-a-chip.

Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients.

Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control.

Cell handling using microstructured membranes.

Universal microfluidic gradient generator.

A high-throughput microfluidic real-time gene expression living cell array.

A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects.

A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings.

Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices.

Continuous inertial focusing, ordering, and separation of particles in microchannels.

Polar stimulation and constrained cell migration in microfluidic channels.

A microfluidic bioreactor for increased active retrovirus output.

Isolation of rare circulating tumour cells in cancer patients by microchip technology.

Equilibrium separation and filtration of particles using differential inertial focusing.

Synthetic microvascular networks for quantitative analysis of particle adhesion.

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.

Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime.

Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells.

'Living cantilever arrays' for characterization of mass of single live cells in fluids.

Detection of mutations in EGFR in circulating lung-cancer cells.

Controlled encapsulation of single-cells into monodisperse picolitre drops.

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

Microvortex for focusing, guiding and sorting of particles.

Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution.

In situ characterization of a cold and short pulsed molecular beam by femtosecond ion imaging.

Adaptive-control model for neutrophil orientation in the direction of chemical gradients.

Nucleation and solidification in static arrays of monodisperse drops.

Chemical gradient-mediated melting curve analysis for genotyping of SNPs.

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.

Cutting edge: electronic counting of white blood cells.

Coherent oscillatory femtosecond dynamics in multichannel photodynamics of NO2 studied by spatially masked electron imaging.

A short pulse (7 micros FWHM) and high repetition rate (dc-5 kHz) cantilever piezovalve for pulsed atomic and molecular beams.

Spontaneous migration of cancer cells under conditions of mechanical confinement.

Genome-wide transcriptome analysis of 150 cell samples.

Microfluidic isolation and transcriptome analysis of serum microvesicles.

MYC regulation of a "poor-prognosis" metastatic cancer cell state.

Microfluidic technologies for temporal perturbations of chemotaxis.

Toward elucidating the mechanism of femtosecond pulse shaping control in photodynamics of molecules by velocity map photoelectron and ion imaging.

Controlled induction of distributed microdeformation in wounded tissue via a microchamber array dressing.

Directional decisions during neutrophil chemotaxis inside bifurcating channels.

Burn injury reduces neutrophil directional migration speed in microfluidic devices.

Clinical microfluidics for neutrophil genomics and proteomics.

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip.

A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration.

Ultrasensitive detection of low-abundance surface-marker protein using isothermal rolling circle amplification in a microfluidic nanoliter platform.

Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients.

The reaction microscope: imaging and pulse shaping control in photodynamics.

Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3.

The Reaction Microscope: Imaging and Pulse Shaping Control in Photodynamics.

Decoding functional metabolomics with docosahexaenoyl ethanolamide (DHEA) identifies novel bioactive signals.

Microfluidic proportional flow controller.

Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform.

On a chip.

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility.

Epithelial cell guidance by self-generated EGF gradients.

Resolvin E2 formation and impact in inflammation resolution.

Photoelectron photoion coincidence imaging of ultrafast control in multichannel molecular dynamics.

Multiple phenotypes in Huntington disease mouse neural stem cells.

A portable chemotaxis platform for short and long term analysis.

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.

Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model.

Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions.

Resolvin D2 restores neutrophil directionality and improves survival after burns.

Mitochondrial localization and the persistent migration of epithelial cancer cells.

Microfluidic chemotaxis platform for differentiating the roles of soluble and bound amyloid-β on microglial accumulation.

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system.

MICROFLUIDIC DEVICE FOR EXAMINING DIRECTIONAL SENSING IN DENDRITIC CELL CHEMOTAXIS.

Desiccation kinetics of biopreservation solutions in microchannels.

Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments.

Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels.

On-demand, competing gradient arrays for neutrophil chemotaxis.

Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model.

Cell migration in confined environments.

A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.

Measuring neutrophil speed and directionality during chemotaxis, directly from a droplet of whole blood.

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia.

Technical Advance: Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay.