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Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis.
Journal of bacteriology Feb, 2002 | Pubmed ID: 11807055
Use of plant and insect hosts to model bacterial pathogenesis.
Methods in enzymology , 2002 | Pubmed ID: 12474375
The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.
Infection and immunity Jul, 2003 | Pubmed ID: 12819096
Pseudomonas aeruginosa-plant root interactions. Pathogenicity, biofilm formation, and root exudation.
Plant physiology Jan, 2004 | Pubmed ID: 14701912
Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2004 | Pubmed ID: 14739337
The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2004 | Pubmed ID: 14983043
Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.
Eukaryotic cell Apr, 2004 | Pubmed ID: 15075271
Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa.
Journal of the American Society for Mass Spectrometry Jun, 2004 | Pubmed ID: 15144975
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones.
Molecular microbiology Feb, 2005 | Pubmed ID: 15686549
Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2005 | Pubmed ID: 15695583
Burn injury causes mitochondrial dysfunction in skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2005 | Pubmed ID: 15809440
Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2005 | Pubmed ID: 16126910
Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry.
Microbiology (Reading, England) Jun, 2006 | Pubmed ID: 16735731
Local and distant burn injury alter immuno-inflammatory gene expression in skeletal muscle.
The Journal of trauma Aug, 2006 | Pubmed ID: 16917440
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial.
Genome biology , 2006 | Pubmed ID: 17038190
MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.
Molecular microbiology Dec, 2006 | Pubmed ID: 17083468
Uncoupling protein 3 expression and intramyocellular lipid accumulation by NMR following local burn trauma.
International journal of molecular medicine Dec, 2006 | Pubmed ID: 17089030
Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa.
PLoS pathogens Mar, 2007 | Pubmed ID: 17367209
Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies.
International journal of molecular medicine Aug, 2007 | Pubmed ID: 17611638
PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline (DHQ), a newly identified metabolite produced by Pseudomonas aeruginosa and Burkholderia thailandensis.
Biological chemistry Aug, 2007 | Pubmed ID: 17655503
Inhibitors of pathogen intercellular signals as selective anti-infective compounds.
PLoS pathogens Sep, 2007 | Pubmed ID: 17941706
Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma.
PloS one , 2007 | Pubmed ID: 18159239
Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn.
International journal of molecular medicine Feb, 2008 | Pubmed ID: 18204786
Use of the lambda Red recombinase system to rapidly generate mutants in Pseudomonas aeruginosa.
BMC molecular biology , 2008 | Pubmed ID: 18248677
Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.
International journal of molecular medicine Jun, 2008 | Pubmed ID: 18506378
Modeling Pseudomonas aeruginosa pathogenesis in plant hosts.
Nature protocols , 2009 | Pubmed ID: 19180083
Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.
International journal of molecular medicine Sep, 2009 | Pubmed ID: 19639232
Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection.
Nature protocols , 2009 | Pubmed ID: 19680242
Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis.
Blood Nov, 2009 | Pubmed ID: 19696201
The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria.
PloS one , 2009 | Pubmed ID: 19779606
Homeostatic interplay between bacterial cell-cell signaling and iron in virulence.
PLoS pathogens Mar, 2010 | Pubmed ID: 20300606
In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling.
International journal of molecular medicine Aug, 2010 | Pubmed ID: 20596596
Combined off-resonance imaging and T2 relaxation in the rotating frame for positive contrast MR imaging of infection in a murine burn model.
Journal of magnetic resonance imaging : JMRI Nov, 2010 | Pubmed ID: 21031524
Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia.
International journal of molecular medicine Jan, 2011 | Pubmed ID: 21069263
Burn trauma in skeletal muscle results in oxidative stress as assessed by in vivo electron paramagnetic resonance.
Molecular medicine reports , 2008 | Pubmed ID: 21179378
Drosophila melanogaster as a model for human intestinal infection and pathology.
Disease models & mechanisms Jan, 2011 | Pubmed ID: 21183483
Combining magnetic resonance spectroscopy and molecular genomics offers better accuracy in brain tumor typing and prediction of survival than either methodology alone.
International journal of oncology Apr, 2011 | Pubmed ID: 21274507
A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes.
PLoS pathogens Aug, 2011 | Pubmed ID: 21829370
Down-regulation of glutatione S-transferase α 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2012 | Pubmed ID: 22038048
1NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School,
2, Shriners Burn Institute,
3Department of Radiology, Athinoula A. Martinos Center of Biomedical Imaging, Harvard Medical School,
4Molecular Surgery Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School
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