Department of Pediatrics,
Division of Neurology,
Department of Pediatrics, Division of Neurology
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Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death.
Endocrinology Mar, 2003 | Pubmed ID: 12586782
c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.
The EMBO journal Oct, 2003 | Pubmed ID: 14517246
A critical role of neural-specific JNK3 for ischemic apoptosis.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2003 | Pubmed ID: 14657393
Modulation of germ cell apoptosis with a nitric oxide synthase inhibitor in a murine model of congenital cryptorchidism.
The Journal of urology Oct, 2004 | Pubmed ID: 15371801
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15564594
Specific pathophysiological functions of JNK isoforms in the brain.
The European journal of neuroscience Jan, 2005 | Pubmed ID: 15673436
Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society Jun, 2005 | Pubmed ID: 15719422
Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy.
Current drug targets. CNS and neurological disorders Feb, 2005 | Pubmed ID: 15723614
Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus.
The European journal of neuroscience Feb, 2005 | Pubmed ID: 15733099
Retinoic acid induces CDK inhibitors and growth arrest specific (Gas) genes in neural crest cells.
Development, growth & differentiation Apr, 2005 | Pubmed ID: 15839997
Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2005 | Pubmed ID: 16157885
Saposin C: neuronal effect and CNS delivery by liposomes.
Annals of the New York Academy of Sciences Aug, 2005 | Pubmed ID: 16179529
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.
The American journal of pathology Aug, 2006 | Pubmed ID: 16877357
The roles of autophagy in cerebral ischemia.
Autophagy Jan-Feb, 2007 | Pubmed ID: 17035724
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17050694
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17060633
Nestin-CreER mice reveal DNA synthesis by nonapoptotic neurons following cerebral ischemia hypoxia.
Cerebral cortex (New York, N.Y. : 1991) Nov, 2007 | Pubmed ID: 17259645
Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2007 | Pubmed ID: 17409253
Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.
Genes & development Sep, 2007 | Pubmed ID: 17875667
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Autophagy Feb, 2008 | Pubmed ID: 18188003
Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice.
Molecular vision , 2008 | Pubmed ID: 18385792
Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia.
The American journal of pathology Jun, 2008 | Pubmed ID: 18467699
Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly.
Developmental biology Jan, 2009 | Pubmed ID: 19007770
JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration.
Journal of neurochemistry Dec, 2008 | Pubmed ID: 19014392
Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway.
The Journal of cell biology Dec, 2008 | Pubmed ID: 19114593
Developmental and post-injury cortical gliogenesis: a genetic fate-mapping study with Nestin-CreER mice.
Glia Aug, 2009 | Pubmed ID: 19115384
Therapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2009 | Pubmed ID: 19587273
Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Apr, 2011 | Pubmed ID: 21139628
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.
Proceedings of the National Academy of Sciences of the United States of America May, 2011 | Pubmed ID: 21502507
Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis.
Journal of neuroscience methods Jan, 2012 | Pubmed ID: 21982741
Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.
Cerebral cortex (New York, N.Y. : 1991) May, 2013 | Pubmed ID: 22556277
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Apr, 2012 | Pubmed ID: 22966490
Intranasal delivery of cell-penetrating anti-NF-κB peptides (Tat-NBD) alleviates infection-sensitized hypoxic-ischemic brain injury.
Experimental neurology Sep, 2013 | Pubmed ID: 23353638
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2013 | Pubmed ID: 23382178
Gsx2 controls region-specific activation of neural stem cells and injury-induced neurogenesis in the adult subventricular zone.
Genes & development Jun, 2013 | Pubmed ID: 23723414
Overexpression of vascular endothelial growth factor in the germinal matrix induces neurovascular proteases and intraventricular hemorrhage.
Science translational medicine Jul, 2013 | Pubmed ID: 23843451
Taming neonatal hypoxic-ischemic brain injury by intranasal delivery of plasminogen activator inhibitor-1.
Stroke; a journal of cerebral circulation Sep, 2013 | Pubmed ID: 23881953
Cell type-specific dependency on the PI3K/Akt signaling pathway for the endogenous Epo and VEGF induction by baicalein in neurons versus astrocytes.
PloS one , 2013 | Pubmed ID: 23904909
Synergy of combined tPA-edaravone therapy in experimental thrombotic stroke.
PloS one , 2014 | Pubmed ID: 24911517
Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2014 | Pubmed ID: 25471584
Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation.
CNS neuroscience & therapeutics Apr, 2015 | Pubmed ID: 25475942
Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease.
PloS one , 2014 | Pubmed ID: 25506911
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Cell Dec, 2014 | Pubmed ID: 25525875
Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.
PloS one , 2014 | Pubmed ID: 25531304
Aryl hydrocarbon receptor mediates both proinflammatory and anti-inflammatory effects in lipopolysaccharide-activated microglia.
Glia Jul, 2015 | Pubmed ID: 25690886
Prophylactic Edaravone Prevents Transient Hypoxic-Ischemic Brain Injury: Implications for Perioperative Neuroprotection.
Stroke; a journal of cerebral circulation Jul, 2015 | Pubmed ID: 26060244
Towards reperfusion-centric preclinical stroke research: outside the box of "reperfusion injury".
Neural regeneration research Apr, 2015 | Pubmed ID: 26170803
Introduction of severe traumatic brain injury care protocol is associated with reduction in mortality for pediatric patients: a case study of Children's Healthcare of Atlanta's neurotrauma program.
Journal of neurosurgery. Pediatrics 08, 2018 | Pubmed ID: 29799350
Plasma osteopontin may predict neuroinflammation and the severity of pediatric traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 01, 2020 | Pubmed ID: 30866741
Early neutrophil infiltration is critical for inflammation-sensitized hypoxic-ischemic brain injury in newborns.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 11, 2020 | Pubmed ID: 31842667
A murine photothrombotic stroke model with an increased fibrin content and improved responses to tPA-lytic treatment.
Blood advances 04, 2020 | Pubmed ID: 32227212
Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke.
Science advances Aug, 2020 | Pubmed ID: 32923636
Monocytic Infiltrates Contribute to Autistic-like Behaviors in a Two-Hit Model of Neurodevelopmental Defects.
The Journal of neuroscience : the official journal of the Society for Neuroscience 12, 2020 | Pubmed ID: 33127853
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury.
Neurobiology of disease 01, 2021 | Pubmed ID: 33248237
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