Chia-Yi Kuan

Chia-Yi Kuan

Department of Pediatrics, The Emory University School of Medicine

Affiliated withThe Emory University School of MedicineUniversity of Virginia School of Medicine

Research Area

MedicineNeuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 3
Year
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Publication title
2015
2021
2025

Other Publications

Article
Year
Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death.

Endocrinology| PubMed ID: 12586782

2003
2003
A critical role of neural-specific JNK3 for ischemic apoptosis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 14657393

2003
2004
Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 15564594

2004
Specific pathophysiological functions of JNK isoforms in the brain.

The European journal of neuroscience| PubMed ID: 15673436

2005
Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 15719422

2005
Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy.

Current drug targets. CNS and neurological disorders| PubMed ID: 15723614

2005
2005
2005
Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16157885

2005
Saposin C: neuronal effect and CNS delivery by liposomes.

Annals of the New York Academy of Sciences| PubMed ID: 16179529

2005
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.

The American journal of pathology| PubMed ID: 16877357

2006
The roles of autophagy in cerebral ischemia.

Autophagy| PubMed ID: 17035724

2007
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17050694

2006
Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17060633

2006
2007
Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 17409253

2007
2007
2008
2008
2008
2009
2008
2008
2009
Therapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 19587273

2009
Ex vivo diffusion tensor imaging and neuropathological correlation in a murine model of hypoxia-ischemia-induced thrombotic stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 21139628

2011
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21502507

2011
2012
2013
2012
2013
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23382178

2013
2013
2013
2013
2013
2014
Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 25471584

2014
2015
2014
2014
2014
2015
2015
2015
2018
Plasma osteopontin may predict neuroinflammation and the severity of pediatric traumatic brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 30866741

2020
Early neutrophil infiltration is critical for inflammation-sensitized hypoxic-ischemic brain injury in newborns.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism| PubMed ID: 31842667

2020
2020
2020
Monocytic Infiltrates Contribute to Autistic-like Behaviors in a Two-Hit Model of Neurodevelopmental Defects.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 33127853

2020
2021
2021
2021
2021
2022
2022
(Phospho)creatine: the reserve and merry-go-round of brain energetics.

Neural regeneration research| PubMed ID: 35900419

2023
2022
2023
2024
2025