Karen K. Hirschi

Diverse roles of the vasculature within the neural stem cell niche.

Transforming growth factor-beta induction of smooth muscle cell phenotpye requires transcriptional and post-transcriptional control of serum response factor.

Quaking is essential for blood vessel development.

Vascular assembly in natural and engineered tissues.

Vascular assembly in engineered and natural tissues: breakout session summary.

Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.

The FAKs about blood vessel assembly.

Phenotype and hematopoietic potential of side population cells throughout embryonic development.

Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation.

Altered phenotype and reduced function of muscle-derived hematopoietic stem cells.

Retinoic acid regulates endothelial cell proliferation during vasculogenesis.

Ouabain- and marinobufagenin-induced proliferation of human umbilical vein smooth muscle cells and a rat vascular smooth muscle cell line, A7r5.

Primitive adult hematopoietic stem cells can function as osteoblast precursors.

Smooth muscle stem cells.

Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation.

Nutrient regulation of cell cycle progression.

Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer.

Red light, green light: signals that control endothelial cell proliferation during embryonic vascular development.

Understanding abnormalities in vascular specification and remodeling.

Visceral endoderm function is regulated by quaking and required for vascular development.

Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3.

Murine neonatal intravascular injections: modeling newborn disease.

Injury mechanism dictates contribution of bone marrow-derived cells to murine hepatic vascular regeneration.

Assessing identity, phenotype, and fate of endothelial progenitor cells.

Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis.

Signaling hierarchy regulating human endothelial cell development.

A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines.

Embryonic vasculogenesis and hematopoietic specification.

Epimorphic regeneration approach to tissue replacement in adult mammals.

Hemato-vascular origins of endothelial progenitor cells?

Vascular precursors: origin, regulation and function.

Vascular potential of human pluripotent stem cells.

Characterization of bacterial artificial chromosome transgenic mice expressing mCherry fluorescent protein substituted for the murine smooth muscle alpha-actin gene.

Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals.

Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo.

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity.

Establishment and regulation of the HSC niche: Roles of osteoblastic and vascular compartments.

The role of quaking in mammalian embryonic development.

Stem cell-derived vascular endothelial cells and their potential application in regenerative medicine.

Cardiovascular regenerative biology.

Hemogenic endothelium during development and beyond.

Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.

Vascular precursor cells.

Vascular progenitor cell mobilization.

Studying vascular progenitor cells in a neonatal mouse model.

Connexin45 regulates endothelial-induced mesenchymal cell differentiation toward a mural cell phenotype.

A computational approach to detect gap junction plaques and associate them with cells in fluorescent images.

Regulation of endothelial cell differentiation and specification.

Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.

Induced pluripotent stem cells for regenerative medicine.

The magic touch: endothelial cells muscle-up adipose.

Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells.

Bioactive poly(ethylene glycol) hydrogels to recapitulate the HSC niche and facilitate HSC expansion in culture.

Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.

Corrigendum: Ionizing Particle Radiation as a Modulator of Endogenous Bone Marrow Cell Reprogramming: Implications for Hematological Cancers.

Specification and function of hemogenic endothelium during embryogenesis.

Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.

Single Cell Analysis in Vascular Biology.

Isolation of Highly Purified and Viable Retinal Endothelial Cells.

Regulation of Hemogenic Endothelial Cell Development and Function.

Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification.

The N-glycome regulates the endothelial-to-hematopoietic transition.

Tissue-Resident Macrophage Development and Function.

Vascular endothelial cell specification in health and disease.

The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.

Understanding neural stem cell regulation and applying the insights to cell therapy for strokes.