Institut Cochin,
Inserm U1016,
Cnrs Umr8104,
Institut Cochin, Inserm U1016, Cnrs Umr8104
Pierre-Olivier Couraud has not added Biography.
If you are Pierre-Olivier Couraud and would like to personalize this page please email our Author Liaison for assistance.
Characterization of genetically modified human retinal pigment epithelial cells developed for in vitro and transplantation studies.
Investigative ophthalmology & visual science Feb, 2002 | Pubmed ID: 11818403
Microvilli-like structures are associated with the internalization of virulent capsulated Neisseria meningitidis into vascular endothelial cells.
Journal of cell science Mar, 2002 | Pubmed ID: 11884522
How do extracellular pathogens cross the blood-brain barrier?
Trends in microbiology May, 2002 | Pubmed ID: 11973156
Lymphocyte trafficking through the blood-brain barrier is dependent on endothelial cell heterotrimeric G-protein signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2002 | Pubmed ID: 12153986
Human adipose cells express CD4, CXCR4, and CCR5 [corrected] receptors: a new target cell type for the immunodeficiency virus-1?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2002 | Pubmed ID: 12153994
Lymphocyte migration into the central nervous system: implication of ICAM-1 signalling at the blood-brain barrier.
Vascular pharmacology Jun, 2002 | Pubmed ID: 12529926
Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells.
Neuroscience letters Jun, 2003 | Pubmed ID: 12782340
JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells.
Blood Nov, 2003 | Pubmed ID: 12869515
Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2003 | Pubmed ID: 12902516
Development and characterization of immortalized cerebral endothelial cell lines.
Methods in molecular medicine , 2003 | Pubmed ID: 12958432
Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15123706
Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions.
Cellular and molecular neurobiology Feb, 2005 | Pubmed ID: 15962508
Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide.
Journal of cell science Aug, 2005 | Pubmed ID: 16076899
[Endothelin-1, angiotensin II and cancer].
Medecine sciences : M/S Apr, 2006 | Pubmed ID: 16597412
Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures.
The Journal of cell biology May, 2006 | Pubmed ID: 16717131
Junctional expression of the prion protein PrPC by brain endothelial cells: a role in trans-endothelial migration of human monocytes.
Journal of cell science Nov, 2006 | Pubmed ID: 17062642
TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells.
Molecular and cellular biology Apr, 2007 | Pubmed ID: 17242194
A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters.
Brain research May, 2007 | Pubmed ID: 17434463
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2007 | Pubmed ID: 17586731
Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Feb, 2008 | Pubmed ID: 17609686
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells.
Journal of neurochemistry Oct, 2007 | Pubmed ID: 17662049
Human blood-brain barrier disruption by retroviral-infected lymphocytes: role of myosin light chain kinase in endothelial tight-junction disorganization.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2007 | Pubmed ID: 17675520
[Functions of prion protein PrPc].
Medecine sciences : M/S Aug-Sep, 2007 | Pubmed ID: 17875293
Regulation of cerebral endothelial cell morphology by extracellular calcium.
Physics in medicine and biology Oct, 2007 | Pubmed ID: 17921584
Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier.
The Journal of physiology Apr, 2008 | Pubmed ID: 18258663
Simvastatin protects against amyloid beta and HIV-1 Tat-induced promoter activities of inflammatory genes in brain endothelial cells.
Molecular pharmacology May, 2008 | Pubmed ID: 18276775
Pcbs and tight junction expression.
Environmental toxicology and pharmacology Mar, 2008 | Pubmed ID: 18438464
Molecular mechanism of systemic delivery of neural precursor cells to the brain: assembly of brain endothelial apical cups and control of transmigration by CD44.
Stem cells (Dayton, Ohio) Jul, 2008 | Pubmed ID: 18450824
Caveolin-1 regulates human immunodeficiency virus-1 Tat-induced alterations of tight junction protein expression via modulation of the Ras signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2008 | Pubmed ID: 18667611
Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells.
Journal of neurochemistry Oct, 2008 | Pubmed ID: 18673450
Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2008 | Pubmed ID: 18714030
Alteration of blood-brain barrier integrity by retroviral infection.
PLoS pathogens Nov, 2008 | Pubmed ID: 19008946
The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.
Journal of neurochemistry Dec, 2008 | Pubmed ID: 19013850
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
Biochemical pharmacology Mar, 2009 | Pubmed ID: 19041851
The blood-brain barrier in brain homeostasis and neurological diseases.
Biochimica et biophysica acta Apr, 2009 | Pubmed ID: 19061857
JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.
The Journal of cell biology Dec, 2008 | Pubmed ID: 19064666
ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.
Journal of neurochemistry Dec, 2008 | Pubmed ID: 19094056
Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment.
Journal of neuroimmunology May, 2009 | Pubmed ID: 19324423
Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.
Science (New York, N.Y.) Jul, 2009 | Pubmed ID: 19520910
Role of KCNMA1 gene in breast cancer invasion and metastasis to brain.
BMC cancer Jul, 2009 | Pubmed ID: 19640305
Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line.
Journal of leukocyte biology Nov, 2009 | Pubmed ID: 19696154
Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies.
Brain research Nov, 2009 | Pubmed ID: 19728990
Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformans.
Eukaryotic cell Nov, 2009 | Pubmed ID: 19767445
Induced secretion of beta-hexosaminidase by human brain endothelial cells: a novel approach in Sandhoff disease?
Neurobiology of disease Mar, 2010 | Pubmed ID: 20005954
Identification of peptide ligands for targeting to the blood-brain barrier.
Pharmaceutical research Apr, 2010 | Pubmed ID: 20162339
IL8 and CXCL13 are potent chemokines for the recruitment of human neural precursor cells across brain endothelial cells.
Journal of neuroimmunology Jun, 2010 | Pubmed ID: 20400187
Design of fluorescently tagged poly(alkyl cyanoacrylate) nanoparticles for human brain endothelial cell imaging.
Chemical communications (Cambridge, England) Apr, 2010 | Pubmed ID: 20449321
A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody.
Journal of cellular physiology Nov, 2010 | Pubmed ID: 20506235
Matrix metalloproteinase 2 (MMP-2) degrades soluble vasculotropic amyloid-beta E22Q and L34V mutants, delaying their toxicity for human brain microvascular endothelial cells.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20576603
Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood-brain barrier integrity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Feb, 2011 | Pubmed ID: 20683453
Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions.
PLoS pathogens Jul, 2010 | Pubmed ID: 20686652
Role of astrocytic leptin receptor subtypes on leptin permeation across hCMEC/D3 human brain endothelial cells.
Journal of neurochemistry Dec, 2010 | Pubmed ID: 20977476
Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2011 | Pubmed ID: 21045812
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown.
PloS one Oct, 2010 | Pubmed ID: 21060661
Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Feb, 2011 | Pubmed ID: 21118722
Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium.
European journal of cell biology Apr, 2011 | Pubmed ID: 21168935
Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues.
Cell and tissue research Mar, 2011 | Pubmed ID: 21191615
Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway.
EMBO reports May, 2011 | Pubmed ID: 21460795
Human brain endothelial cells are responsive to adenosine receptor activation.
Purinergic signalling Jun, 2011 | Pubmed ID: 21484089
Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models.
Journal of neuroscience methods Aug, 2011 | Pubmed ID: 21609734
Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.
Molecular pharmaceutics Aug, 2011 | Pubmed ID: 21707071
Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide.
Journal of biotechnology Dec, 2011 | Pubmed ID: 21763360
Insights into the pathogenesis of systemic sclerosis based on the gene expression profile of progenitor-derived endothelial cells.
Arthritis and rheumatism Nov, 2011 | Pubmed ID: 21769840
Insights into the putative catechin and epicatechin transport across blood-brain barrier.
Food & function Jan, 2011 | Pubmed ID: 21773584
Invading basement membrane matrix is sufficient for MDA-MB-231 breast cancer cells to develop a stable in vivo metastatic phenotype.
PloS one , 2011 | Pubmed ID: 21858074
Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3.
Purinergic signalling Mar, 2012 | Pubmed ID: 21956217
A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells.
Journal of proteomics Dec, 2011 | Pubmed ID: 21982828
The metastatic microenvironment: brain-residing melanoma metastasis and dormant micrometastasis.
International journal of cancer Sep, 2012 | Pubmed ID: 22025079
Angiogenic biomarkers predict the occurrence of digital ulcers in systemic sclerosis.
Annals of the rheumatic diseases Mar, 2012 | Pubmed ID: 22085793
Hepatitis C virus infects the endothelial cells of the blood-brain barrier.
Gastroenterology Mar, 2012 | Pubmed ID: 22138189
Lamotrigine is a substrate for OCT1 in brain endothelial cells.
Biochemical pharmacology Mar, 2012 | Pubmed ID: 22227272
Guanine nucleotide-binding protein Gαi2: a new partner of claudin-5 that regulates tight junction integrity in human brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2012 | Pubmed ID: 22333621
The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine.
Molecular pharmaceutics Apr, 2012 | Pubmed ID: 22352408
Expression and localization of claudins-3 and -12 in transformed human brain endothelium.
Fluids and barriers of the CNS Feb, 2012 | Pubmed ID: 22373538
[Transendothelial migration through the neurovascular unit: "a cup to cross the barrier"].
Medecine sciences : M/S Feb, 2012 | Pubmed ID: 22377292
The metastatic microenvironment: Brain-derived soluble factors alter the malignant phenotype of cutaneous and brain-metastasizing melanoma cells.
International journal of cancer. Journal international du cancer Dec, 2012 | Pubmed ID: 22447293
Angiotensin II facilitates breast cancer cell migration and metastasis.
PloS one , 2012 | Pubmed ID: 22536420
CCL2 disrupts the adherens junction: implications for neuroinflammation.
Laboratory investigation; a journal of technical methods and pathology Aug, 2012 | Pubmed ID: 22641100
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2012 | Pubmed ID: 22730440
Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells.
Particle and fibre toxicology Jul, 2012 | Pubmed ID: 22759355
Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model.
PloS one , 2012 | Pubmed ID: 22984556
Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro.
PloS one , 2012 | Pubmed ID: 23029348
Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier.
Journal of neuroscience methods Jan, 2013 | Pubmed ID: 23068604
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.
Molecular pharmaceutics Jan, 2013 | Pubmed ID: 23137377
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation.
Fluids and barriers of the CNS Nov, 2012 | Pubmed ID: 23140302
Cooperation between β- and γ-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2013 | Pubmed ID: 23159932
The brain microvascular endothelium supports T cell proliferation and has potential for alloantigen presentation.
PloS one , 2013 | Pubmed ID: 23320074
TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier.
Journal of neuroinflammation , 2013 | Pubmed ID: 23320797
Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model.
Fluids and barriers of the CNS Jan, 2013 | Pubmed ID: 23351963
The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients.
Vascular cell , 2013 | Pubmed ID: 23388410
High-density lipoprotein-based therapy reduces the hemorrhagic complications associated with tissue plasminogen activator treatment in experimental stroke.
Stroke; a journal of cerebral circulation Mar, 2013 | Pubmed ID: 23422087
Glial-cell-mediated re-induction of the blood-brain barrier phenotype in brain capillary endothelial cells: a differential gel electrophoresis study.
Proteomics Apr, 2013 | Pubmed ID: 23436736
Overexpression of CD44 in neural precursor cells improves trans-endothelial migration and facilitates their invasion of perivascular tissues in vivo.
PloS one , 2013 | Pubmed ID: 23468987
The hCMEC/D3 cell line as a model of the human blood brain barrier.
Fluids and barriers of the CNS Mar, 2013 | Pubmed ID: 23531482
Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS.
Scientific reports , 2013 | Pubmed ID: 23595028
Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells.
Microbial pathogenesis Aug-Sep, 2013 | Pubmed ID: 23665198
A multi-system approach assessing the interaction of anticonvulsants with P-gp.
PloS one , 2013 | Pubmed ID: 23741405
Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis.
Biochemical pharmacology Aug, 2013 | Pubmed ID: 23770458
Temozolomide down-regulates P-glycoprotein in human blood-brain barrier cells by disrupting Wnt3 signaling.
Cellular and molecular life sciences : CMLS Feb, 2014 | Pubmed ID: 23771630
Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia.
Cerebrovascular diseases (Basel, Switzerland) , 2013 | Pubmed ID: 23817219
Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro.
PloS one , 2013 | Pubmed ID: 23940549
Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma.
Journal of neuroimmunology Dec, 2013 | Pubmed ID: 24090655
Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles.
The Analyst Mar, 2014 | Pubmed ID: 24195103
The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Mar, 2014 | Pubmed ID: 24346691
Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes.
PloS one , 2014 | Pubmed ID: 24392113
Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C.
PloS one , 2014 | Pubmed ID: 24505408
CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro.
American journal of physiology. Endocrinology and metabolism May, 2014 | Pubmed ID: 24619879
Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.
PloS one , 2014 | Pubmed ID: 24646764
Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
BMC neuroscience Apr, 2014 | Pubmed ID: 24755281
Primary angiitis of the central nervous system: description of the first fifty-two adults enrolled in the French cohort of patients with primary vasculitis of the central nervous system.
Arthritis & rheumatology (Hoboken, N.J.) May, 2014 | Pubmed ID: 24782189
Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization.
Nature medicine Jul, 2014 | Pubmed ID: 24880614
The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Aug, 2014 | Pubmed ID: 24896565
Nanoparticle formulation improves the anticonvulsant effect of clonazepam on the pentylenetetrazole-induced seizures: behavior and electroencephalogram.
Journal of pharmaceutical sciences Aug, 2014 | Pubmed ID: 24916334
Synthesis and in vitro evaluation of BBB permeability, tumor cell uptake, and cytotoxicity of a series of carboranylporphyrin conjugates.
Journal of medicinal chemistry Aug, 2014 | Pubmed ID: 25029034
Edaravone protects against methylglyoxal-induced barrier damage in human brain endothelial cells.
PloS one , 2014 | Pubmed ID: 25033388
The metastatic microenvironment: Claudin-1 suppresses the malignant phenotype of melanoma brain metastasis.
International journal of cancer Mar, 2015 | Pubmed ID: 25046141
The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family.
The AAPS journal Nov, 2014 | Pubmed ID: 25155823
In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells.
PloS one , 2014 | Pubmed ID: 25187991
Permeability of PEGylated immunoarsonoliposomes through in vitro blood brain barrier-medulloblastoma co-culture models for brain tumor therapy.
Pharmaceutical research Mar, 2015 | Pubmed ID: 25236341
Carrier-mediated cocaine transport at the blood-brain barrier as a putative mechanism in addiction liability.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) Jan, 2015 | Pubmed ID: 25539501
Astrocytes facilitate melanoma brain metastasis via secretion of IL-23.
The Journal of pathology May, 2015 | Pubmed ID: 25639230
Contribution of pannexin 1 and connexin 43 hemichannels to extracellular calcium-dependent transport dynamics in human blood-brain barrier endothelial cells.
The Journal of pharmacology and experimental therapeutics Apr, 2015 | Pubmed ID: 25670633
Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier.
The Journal of general virology Jul, 2015 | Pubmed ID: 25711966
Vemurafenib resistance selects for highly malignant brain and lung-metastasizing melanoma cells.
Cancer letters May, 2015 | Pubmed ID: 25725450
Development of a solvent-free analytical method for paracetamol quantitative determination in Blood Brain Barrier in vitro model.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Apr, 2015 | Pubmed ID: 25734939
Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2015 | Pubmed ID: 25769924
Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure.
Brain research Jul, 2015 | Pubmed ID: 25858487
Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4.
International immunology Nov, 2015 | Pubmed ID: 25957268
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis.
Virulence , 2015 | Pubmed ID: 26407066
The hunt for brain Aβ oligomers by peripherally circulating multi-functional nanoparticles: Potential therapeutic approach for Alzheimer disease.
Nanomedicine : nanotechnology, biology, and medicine Jan, 2016 | Pubmed ID: 26410276
Immuno-analysis of microparticles: probing at the limits of detection.
Scientific reports Nov, 2015 | Pubmed ID: 26553743
Solid lipid nanoparticles as a vehicle for brain-targeted drug delivery: two new strategies of functionalization with apolipoprotein E.
Nanotechnology Dec, 2015 | Pubmed ID: 26574295
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free radical biology & medicine Jan, 2016 | Pubmed ID: 26577177
Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development.
Pain Apr, 2016 | Pubmed ID: 26655733
Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?
Scientific reports Feb, 2016 | Pubmed ID: 26837706
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2016 | Pubmed ID: 26868179
Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes through the Blood-Brain Barrier.
Journal of virology Aug, 2016 | Pubmed ID: 27252538
Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier.
International journal of molecular sciences , 2016 | Pubmed ID: 27294916
Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells.
Cellular and molecular life sciences : CMLS Jul, 2016 | Pubmed ID: 27376435
[Research funding: a bottleneck for economic growth].
Medecine sciences : M/S 8-9, 2016 | Pubmed ID: 27615162
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados