Photonics Group,
Department of Physics,
Photonics Group, Department of Physics
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Adaptive aberration correction in a confocal microscope.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2002 | Pubmed ID: 11959908
Active aberration correction for the writing of three-dimensional optical memory devices.
Applied optics Mar, 2002 | Pubmed ID: 11902148
New modal wave-front sensor: application to adaptive confocal fluorescence microscopy and two-photon excitation fluorescence microscopy.
Journal of the Optical Society of America. A, Optics, image science, and vision Oct, 2002 | Pubmed ID: 12365630
Dynamic axial-position control of a laser-trapped particle by wave-front modification.
Optics letters Mar, 2003 | Pubmed ID: 12659281
Fluorescence imaging of two-photon linear dichroism: cholesterol depletion disrupts molecular orientation in cell membranes.
Biophysical journal Jan, 2005 | Pubmed ID: 15520272
Quantitative 3D mapping of fluidic temperatures within microchannel networks using fluorescence lifetime imaging.
Analytical chemistry Apr, 2006 | Pubmed ID: 16579608
Fluorescence lifetime imaging provides enhanced contrast when imaging the phase-sensitive dye di-4-ANEPPDHQ in model membranes and live cells.
Biophysical journal Jun, 2006 | Pubmed ID: 16617080
Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses.
The Journal of cell biology Jul, 2006 | Pubmed ID: 16801390
Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2006 | Pubmed ID: 17142745
Rapid hyperspectral fluorescence lifetime imaging.
Microscopy research and technique May, 2007 | Pubmed ID: 17366615
Fluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systems.
Angewandte Chemie (International ed. in English) , 2007 | Pubmed ID: 17436333
Optical techniques for imaging membrane lipid microdomains in living cells.
Seminars in cell & developmental biology Oct, 2007 | Pubmed ID: 17728161
Fluorescence lifetime imaging by using time-gated data acquisition.
Applied optics Oct, 2007 | Pubmed ID: 17952172
Method for the generation of arbitrary complex vector wave fronts.
Optics letters Nov, 2002 | Pubmed ID: 18033405
Excitation-resolved hyperspectral fluorescence lifetime imaging using a UV-extended supercontinuum source.
Optics letters Dec, 2007 | Pubmed ID: 18059949
Stimulated emission depletion microscopy with a supercontinuum source and fluorescence lifetime imaging.
Optics letters Jan, 2008 | Pubmed ID: 18197209
Improved sectioning in a slit scanning confocal microscope.
Optics letters Aug, 2008 | Pubmed ID: 18709096
Three-dimensional molecular mapping in a microfluidic mixing device using fluorescence lifetime imaging.
Optics letters Aug, 2008 | Pubmed ID: 18709122
High-speed high-resolution imaging of intercellular immune synapses using optical tweezers.
Biophysical journal Nov, 2008 | Pubmed ID: 18723590
Multiplexed FRET to image multiple signaling events in live cells.
Biophysical journal Nov, 2008 | Pubmed ID: 18757561
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets.
Analytical chemistry Jan, 2009 | Pubmed ID: 19055421
Laser-pumped endoscopic illumination source.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference , 2008 | Pubmed ID: 19163100
Live cell linear dichroism imaging reveals extensive membrane ruffling within the docking structure of natural killer cell immune synapses.
Biophysical journal Jan, 2009 | Pubmed ID: 19167281
Fluorescence lifetime optical projection tomography.
Journal of biophotonics Oct, 2008 | Pubmed ID: 19343662
A compact, multidimensional spectrofluorometer exploiting supercontinuum generation.
Journal of biophotonics Dec, 2008 | Pubmed ID: 19343675
High speed unsupervised fluorescence lifetime imaging confocal multiwell plate reader for high content analysis.
Journal of biophotonics Dec, 2008 | Pubmed ID: 19343677
A microfluidic platform for probing single cell plasma membranes using optically trapped Smart Droplet Microtools (SDMs).
Lab on a chip Apr, 2009 | Pubmed ID: 19350091
A fluorescence lifetime imaging scanning confocal endomicroscope.
Journal of biophotonics Jan, 2010 | Pubmed ID: 19787682
Multi-site optical excitation using ChR2 and micro-LED array.
Journal of neural engineering Feb, 2010 | Pubmed ID: 20075504
Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse.
Science signaling , 2010 | Pubmed ID: 20460647
High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells.
Molecular membrane biology Aug, 2010 | Pubmed ID: 20540668
Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.
Molecular and cellular biology Mar, 2011 | Pubmed ID: 21245382
Wide-field fluorescence lifetime imaging of cancer.
Biomedical optics express Aug, 2010 | Pubmed ID: 21258496
FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ.
Chemphyschem : a European journal of chemical physics and physical chemistry Feb, 2011 | Pubmed ID: 21337485
A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection.
Lab on a chip Apr, 2011 | Pubmed ID: 21347466
Adaptive phase compensation for ultracompact laser scanning endomicroscopy.
Optics letters May, 2011 | Pubmed ID: 21540976
Interferometry using binary holograms without high order diffraction effects.
Optics letters Jun, 2011 | Pubmed ID: 21686019
Multimodal biophotonic workstation for live cell analysis.
Journal of biophotonics Jan, 2012 | Pubmed ID: 21842486
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.
PLoS biology Sep, 2011 | Pubmed ID: 21931537
Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging.
Optics express Jul, 2011 | Pubmed ID: 21934746
Quantification of cellular autofluorescence of human skin using multiphoton tomography and fluorescence lifetime imaging in two spectral detection channels.
Biomedical optics express Dec, 2011 | Pubmed ID: 22162820
In vivo measurements of diffuse reflectance and time-resolved autofluorescence emission spectra of basal cell carcinomas.
Journal of biophotonics Mar, 2012 | Pubmed ID: 22308093
Multiphoton multispectral fluorescence lifetime tomography for the evaluation of basal cell carcinomas.
PloS one , 2012 | Pubmed ID: 22984428
Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.
Journal of biophotonics May, 2013 | Pubmed ID: 23184449
Double pass, common path method for arbitrary polarization control using a ferroelectric liquid crystal spatial light modulator.
Optics letters Apr, 2013 | Pubmed ID: 23546237
Scaling advantages and constraints in miniaturized capture assays for single cell protein analysis.
Lab on a chip Jun, 2013 | Pubmed ID: 23592024
3-D stimulated emission depletion microscopy with programmable aberration correction.
Journal of biophotonics Jan, 2014 | Pubmed ID: 23788459
Absolute quantification of protein copy number using a single-molecule-sensitive microarray.
The Analyst Jul, 2014 | Pubmed ID: 24676423
The grab-and-drop protocol: a novel strategy for membrane protein isolation and reconstitution from single cells.
The Analyst Jul, 2014 | Pubmed ID: 24706068
Experimental proof of concept of nanoparticle-assisted STED.
Nano letters Aug, 2014 | Pubmed ID: 25053232
Analysis of DNA binding and nucleotide flipping kinetics using two-color two-photon fluorescence lifetime imaging microscopy.
Analytical chemistry Nov, 2014 | Pubmed ID: 25303623
Correction Approach for Delta Function Convolution Model Fitting of Fluorescence Decay Data in the Case of a Monoexponential Reference Fluorophore.
Journal of fluorescence Sep, 2015 | Pubmed ID: 26063535
Sonic hedgehog multimerization: a self-organizing event driven by post-translational modifications?
Molecular membrane biology , 2015 | Pubmed ID: 26312641
Tunable fibre-coupled multiphoton microscopy with a negative curvature fibre.
Journal of biophotonics Jul, 2016 | Pubmed ID: 26989868
easySTORM: a robust, lower-cost approach to localisation and TIRF microscopy.
Journal of biophotonics Sep, 2016 | Pubmed ID: 27592533
Adaptive multiphoton endomicroscopy through a dynamically deformed multicore optical fiber using proximal detection.
Optics express Sep, 2016 | Pubmed ID: 27661887
Optically assembled droplet interface bilayer (OptiDIB) networks from cell-sized microdroplets.
Soft matter Sep, 2016 | Pubmed ID: 27722718
Plasmonic Nanoprobes for Stimulated Emission Depletion Nanoscopy.
ACS nano Nov, 2016 | Pubmed ID: 27794591
Frederik Görlitz*,1,
Douglas J. Kelly*,1,
Sean C. Warren1,
Dominic Alibhai2,
Lucien West3,
Sunil Kumar1,
Yuriy Alexandrov1,
Ian Munro1,
Edwin Garcia1,
James McGinty1,
Clifford Talbot1,
Remigiusz A. Serwa4,
Emmanuelle Thinon4,
Vincenzo da Paola3,
Edward J. Murray5,
Frank Stuhmeier6,
Mark A. A. Neil1,
Edward W. Tate4,
Christopher Dunsby1,7,
Paul M. W. French1
1Photonics Group, Department of Physics, Imperial College London,
2Institute for Chemical Biology, Department of Chemistry, Imperial College London,
3MRC Clinical Sciences Centre, Hammersmith Hospital,
4Chemical Biology Section, Department of Chemistry, Imperial College London,
5, Retroscreen Virology Ltd,
6Pfizer Global Research and Development, Pfizer Limited, Sandwich, Kent, UK,
7Centre for Histopathology, Imperial College London
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