Photonics Group,
Department of Physics,
Centre for Histopathology,
Photonics Group, Department of Physics
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Fluorescence lifetime imaging provides enhanced contrast when imaging the phase-sensitive dye di-4-ANEPPDHQ in model membranes and live cells.
Biophysical journal Jun, 2006 | Pubmed ID: 16617080
Tissue characterization using dimensionality reduction and fluorescence imaging.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention , 2006 | Pubmed ID: 17354820
Rapid hyperspectral fluorescence lifetime imaging.
Microscopy research and technique May, 2007 | Pubmed ID: 17366615
Excitation-resolved hyperspectral fluorescence lifetime imaging using a UV-extended supercontinuum source.
Optics letters Dec, 2007 | Pubmed ID: 18059949
Stimulated emission depletion microscopy with a supercontinuum source and fluorescence lifetime imaging.
Optics letters Jan, 2008 | Pubmed ID: 18197209
Three-dimensional molecular mapping in a microfluidic mixing device using fluorescence lifetime imaging.
Optics letters Aug, 2008 | Pubmed ID: 18709122
High-speed high-resolution imaging of intercellular immune synapses using optical tweezers.
Biophysical journal Nov, 2008 | Pubmed ID: 18723590
Multiplexed FRET to image multiple signaling events in live cells.
Biophysical journal Nov, 2008 | Pubmed ID: 18757561
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets.
Analytical chemistry Jan, 2009 | Pubmed ID: 19055421
Fluorescence lifetime optical projection tomography.
Journal of biophotonics Oct, 2008 | Pubmed ID: 19343662
Single-shot phase-stepped wide-field coherencegated imaging.
Optics express Jan, 2003 | Pubmed ID: 19461712
Removal of background signals from fluorescence thermometry measurements in PDMS microchannels using fluorescence lifetime imaging.
Lab on a chip Dec, 2009 | Pubmed ID: 19904413
Response of rigor cross-bridges to stretch detected by fluorescence lifetime imaging microscopy of myosin essential light chain in skeletal muscle fibers.
The Journal of biological chemistry Jan, 2011 | Pubmed ID: 21056977
Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pathway.
Nucleic acids research Apr, 2011 | Pubmed ID: 21112870
Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.
Molecular and cellular biology Mar, 2011 | Pubmed ID: 21245382
Quantitative evaluation of healthy epidermis by means of multiphoton microscopy and fluorescence lifetime imaging microscopy.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Aug, 2011 | Pubmed ID: 21518012
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.
PLoS biology Sep, 2011 | Pubmed ID: 21931537
Shear wave elasticity imaging based on acoustic radiation force and optical detection.
Ultrasound in medicine & biology Sep, 2012 | Pubmed ID: 22749816
Ultrasound-mediated optical tomography: a review of current methods.
Interface focus Aug, 2011 | Pubmed ID: 22866234
Multiphoton laser tomography and fluorescence lifetime imaging of basal cell carcinoma: morphologic features for non-invasive diagnostics.
Experimental dermatology Nov, 2012 | Pubmed ID: 22882324
High-resolution imaging of basal cell carcinoma: a comparison between multiphoton microscopy with fluorescence lifetime imaging and reflectance confocal microscopy.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Feb, 2013 | Pubmed ID: 22970856
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF.
Journal of cell science Dec, 2012 | Pubmed ID: 22992460
Detection of cartilage matrix degradation by autofluorescence lifetime.
Matrix biology : journal of the International Society for Matrix Biology Jan, 2013 | Pubmed ID: 23266527
High resolution diagnosis of common nevi by multiphoton laser tomography and fluorescence lifetime imaging.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) May, 2013 | Pubmed ID: 23279266
High-resolution multiphoton tomography and fluorescence lifetime imaging of UVB-induced cellular damage on cultured fibroblasts producing fibres.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Aug, 2013 | Pubmed ID: 23590582
Multiphoton laser tomography and fluorescence lifetime imaging of melanoma: morphologic features and quantitative data for sensitive and specific non-invasive diagnostics.
PloS one , 2013 | Pubmed ID: 23923016
A flexible wide-field FLIM endoscope utilising blue excitation light for label-free contrast of tissue.
Journal of biophotonics Jan, 2015 | Pubmed ID: 24573953
Experimental proof of concept of nanoparticle-assisted STED.
Nano letters Aug, 2014 | Pubmed ID: 25053232
In vivo acoustic super-resolution and super-resolved velocity mapping using microbubbles.
IEEE transactions on medical imaging Feb, 2015 | Pubmed ID: 25265604
Analysis of DNA binding and nucleotide flipping kinetics using two-color two-photon fluorescence lifetime imaging microscopy.
Analytical chemistry Nov, 2014 | Pubmed ID: 25303623
Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.
Advances in biological regulation Jan, 2016 | Pubmed ID: 26482290
Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
Scientific reports Jun, 2016 | Pubmed ID: 27339025
Corrigendum: Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
Scientific reports Sep, 2016 | Pubmed ID: 27654516
Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.
Scientific reports Jan, 2017 | Pubmed ID: 28045057
Frederik Görlitz*,1,
Douglas J. Kelly*,1,
Sean C. Warren1,
Dominic Alibhai2,
Lucien West3,
Sunil Kumar1,
Yuriy Alexandrov1,
Ian Munro1,
Edwin Garcia1,
James McGinty1,
Clifford Talbot1,
Remigiusz A. Serwa4,
Emmanuelle Thinon4,
Vincenzo da Paola3,
Edward J. Murray5,
Frank Stuhmeier6,
Mark A. A. Neil1,
Edward W. Tate4,
Christopher Dunsby1,7,
Paul M. W. French1
1Photonics Group, Department of Physics, Imperial College London,
2Institute for Chemical Biology, Department of Chemistry, Imperial College London,
3MRC Clinical Sciences Centre, Hammersmith Hospital,
4Chemical Biology Section, Department of Chemistry, Imperial College London,
5, Retroscreen Virology Ltd,
6Pfizer Global Research and Development, Pfizer Limited, Sandwich, Kent, UK,
7Centre for Histopathology, Imperial College London
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