Robert Sikes

The role of insulin-like growth factor-II in cancer growth and progression evidenced by the use of ribozymes and prostate cancer progression models.

Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.

Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1/mac 25) is reduced in human prostate cancer and is inversely related to tumor volume and proliferation index in Lucap 23.12 xenografts.

Voltage-gated sodium channel blockers as cytostatic inhibitors of the androgen-independent prostate cancer cell line PC-3.

Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate.

Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer.

Therapeutic approaches targeting prostate cancer progression using novel voltage-gated ion channel blockers.

Cancer cells homing to bone: the significance of chemotaxis and cell adhesion.

Cellular interactions in the tropism of prostate cancer to bone.

Thalidomide and analogues: current proposed mechanisms and therapeutic usage.

Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model.

Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo.

Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.

Voltage-sensitive ion channels and cancer.

Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells.

Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model.

Distribution and properties of visceral nociceptive neurons in rabbit cingulate cortex.

Norepinephrinergic afferents and cytology of the macaque monkey midline, mediodorsal, and intralaminar thalamic nuclei.

Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha.

Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.

Quantitative modeling and analysis of the transforming growth factor beta signaling pathway.

Variation in digestive efficiency of captive North American river otters (Lontra canadensis) on various diets.

Osteosclerotic prostate cancer metastasis to murine bone are enhanced with increased bone formation.

Human prostate fibroblasts induce growth and confer castration resistance and metastatic potential in LNCaP Cells.

Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions.

The developmental expression profile of PAX2 in the murine prostate.

Short-term intermittent PTH 1-34 administration enhances bone formation in SCID/Beige mice.

Nociceptive processing by anterior cingulate pyramidal neurons.

Androgen mediated translational and postranslational regulation of IGFBP-2 in androgen-sensitive LNCaP human prostate cancer cells.

Osteoblasts can stimulate prostate cancer growth and transcriptionally down-regulate PSA expression in cell line models.

Paracrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells.

Energy digestibility of giant pandas on bamboo-only and on supplemented diets.

Organization of somatosensory cortex in the Northern grasshopper mouse (Onychomys leucogaster), a predatory rodent.

Effect of moderate-to-severe chronic kidney disease on flow-mediated dilation and progenitor cells.

Overexpression of the VSSC-associated CAM, beta-2, enhances LNCaP cell metastasis associated behavior.

Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling.