School of Pharmacy
Jeung Whan Han has not added Biography.
If you are Jeung Whan Han and would like to personalize this page please email our Author Liaison for assistance.
Cooperation of H2O2-mediated ERK activation with Smad pathway in TGF-beta1 induction of p21WAF1/Cip1.
Cellular signalling Feb, 2006 | Pubmed ID: 15979845
Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells.
The Journal of biological chemistry Jan, 2002 | Pubmed ID: 11698395
Autotaxin promotes motility via G protein-coupled phosphoinositide 3-kinase gamma in human melanoma cells.
FEBS letters Mar, 2002 | Pubmed ID: 11943209
Oligosaccharide-linked acyl carrier protein, a novel transmethylase inhibitor, from porcine liver inhibits cell growth.
Archives of pharmacal research Aug, 2002 | Pubmed ID: 12214857
5-Fluorouracil inhibits nitric oxide production through the inactivation of IkappaB kinase in stomach cancer cells.
Biochemical pharmacology Nov, 2002 | Pubmed ID: 12417257
Constitutive activation of p70S6k in cancer cells.
Archives of pharmacal research Oct, 2002 | Pubmed ID: 12433206
Doxorubicin inhibits the production of nitric oxide by colorectal cancer cells.
Archives of pharmacal research Oct, 2002 | Pubmed ID: 12433207
Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058 melanoma cells.
FEBS letters Dec, 2002 | Pubmed ID: 12482591
Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells.
Clinical & experimental metastasis , 2002 | Pubmed ID: 12498389
Purification and characterization of nitric oxide synthase from Staphylococcus aureus.
FEMS microbiology letters May, 2003 | Pubmed ID: 12770704
Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires PI 3-kinase-PKC epsilon signaling pathway.
Oncogene Sep, 2003 | Pubmed ID: 12955081
Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase.
Experimental cell research Oct, 2003 | Pubmed ID: 14516795
Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials.
Biochemical and biophysical research communications Mar, 2004 | Pubmed ID: 14985106
Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells.
European journal of biochemistry Apr, 2004 | Pubmed ID: 15066181
In-vitro and in-vivo anti-allergic actions of Arecae semen.
The Journal of pharmacy and pharmacology Jul, 2004 | Pubmed ID: 15233873
Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr.
Molecular and cellular biology Aug, 2004 | Pubmed ID: 15282299
Hydrogen peroxide mediates Rac1 activation of S6K1.
Experimental cell research Nov, 2004 | Pubmed ID: 15475011
Inhibitory activity of Chrysanthemi sibirici herba extract on RBL-2H3 mast cells and compound 48/80-induced anaphylaxis.
Journal of ethnopharmacology Dec, 2004 | Pubmed ID: 15507370
Development of a liquid chromatography/electrospray tandem mass spectrometry assay for the quantification of apicidin, a novel histone deacetylase inhibitor, in rat serum: application to a pharmacokinetic study.
Rapid communications in mass spectrometry : RCM , 2005 | Pubmed ID: 15645510
Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages.
International immunopharmacology May, 2005 | Pubmed ID: 15778128
p85 beta-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase.
Experimental cell research Jul, 2005 | Pubmed ID: 15893751
beta-Carboline alkaloid suppresses NF-kappaB transcriptional activity through inhibition of IKK signaling pathway.
Journal of toxicology and environmental health. Part A Dec, 2005 | Pubmed ID: 16326420
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones.
Journal of toxicology and environmental health. Part A Dec, 2005 | Pubmed ID: 16326428
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells.
The Journal of biological chemistry Feb, 2006 | Pubmed ID: 16326706
Apoptotic potential of sesquiterpene lactone ergolide through the inhibition of NF-kappaB signaling pathway.
The Journal of pharmacy and pharmacology Dec, 2005 | Pubmed ID: 16354403
Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites.
Biochemical and biophysical research communications Apr, 2006 | Pubmed ID: 16516150
Rubiae Radix suppresses the activation of mast cells through the inhibition of Syk kinase for anti-allergic activity.
The Journal of pharmacy and pharmacology Apr, 2006 | Pubmed ID: 16597368
Immunoglobulin can be functionally regulated by protein carboxylmethylation in Fc region.
Archives of pharmacal research May, 2006 | Pubmed ID: 16756083
Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells.
Blood Aug, 2006 | Pubmed ID: 16861349
Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kappaB activation by the HDAC inhibitor apicidin.
Biochemical and biophysical research communications Sep, 2006 | Pubmed ID: 16870149
Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-nuclear [corrected] factor kappa B signaling cascade in human melanoma cells.
Melanoma research Oct, 2006 | Pubmed ID: 17013094
Activation of hypoxia-inducible factor-1alpha is necessary for lysophosphatidic acid-induced vascular endothelial growth factor expression.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2006 | Pubmed ID: 17085645
PKCepsilon is essential for gelsolin expression by histone deacetylase inhibitor apicidin in human cervix cancer cells.
Biochemical and biophysical research communications Mar, 2007 | Pubmed ID: 17257588
Reversal of multidrug resistance by 4-chloro-N-(3-((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)phenyl)benzamide through the reversible inhibition of P-glycoprotein.
Biochemical and biophysical research communications Mar, 2007 | Pubmed ID: 17286965
Coordinated change of a ratio of methylated H3-lysine 4 or acetylated H3 to acetylated H4 and DNA methylation is associated with tissue-specific gene expression in cloned pig.
Experimental & molecular medicine Feb, 2007 | Pubmed ID: 17334232
Meliae cortex extract exhibits anti-allergic activity through the inhibition of Syk kinase in mast cells.
Toxicology and applied pharmacology May, 2007 | Pubmed ID: 17395225
Suppression of the NF-kappaB signalling pathway by ergolide, sesquiterpene lactone, in HeLa cells.
The Journal of pharmacy and pharmacology Apr, 2007 | Pubmed ID: 17430640
Reversine stimulates adipocyte differentiation and downregulates Akt and p70(s6k) signaling pathways in 3T3-L1 cells.
Biochemical and biophysical research communications Jun, 2007 | Pubmed ID: 17490611
Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.
Bioorganic & medicinal chemistry letters Nov, 2007 | Pubmed ID: 17904843
Histone chaperones regulate histone exchange during transcription.
The EMBO journal Oct, 2007 | Pubmed ID: 17914459
Hypoxia enhances LPA-induced HIF-1alpha and VEGF expression: their inhibition by resveratrol.
Cancer letters Dec, 2007 | Pubmed ID: 17919812
Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein.
Biochemical and biophysical research communications Apr, 2008 | Pubmed ID: 18275843
Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk.
The Journal of allergy and clinical immunology May, 2008 | Pubmed ID: 18394691
TIMP-2 disrupts FGF-2-induced downstream signaling pathways.
Microvascular research Nov, 2008 | Pubmed ID: 18721821
Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model.
Experimental & molecular medicine Oct, 2008 | Pubmed ID: 18985016
Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 19015271
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
Experimental & molecular medicine Dec, 2008 | Pubmed ID: 19116446
Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation.
Biological & pharmaceutical bulletin Jun, 2009 | Pubmed ID: 19483303
Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression.
Cancer research Jul, 2009 | Pubmed ID: 19567677
Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway.
Journal of pharmacological sciences Sep, 2009 | Pubmed ID: 19763044
A novel gamma-lactam-based histone deacetylase inhibitor potently inhibits the growth of human breast and renal cancer cells.
Biological & pharmaceutical bulletin Oct, 2009 | Pubmed ID: 19801834
The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.
Nucleic acids research Jan, 2010 | Pubmed ID: 19906718
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival.
Stem cells (Dayton, Ohio) Mar, 2010 | Pubmed ID: 20049900
HDAC inhibitors downregulate MRP2 expression in multidrug resistant cancer cells: implication for chemosensitization.
International journal of oncology Mar, 2011 | Pubmed ID: 21170509
Myogenic transcriptional activation of MyoD mediated by replication-independent histone deposition.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21173268
Histone chaperones cooperate to mediate Mef2-targeted transcriptional regulation during skeletal myogenesis.
Biochemical and biophysical research communications Apr, 2011 | Pubmed ID: 21414300
Requirement of protein l-isoaspartyl O-methyltransferase for transcriptional activation of trefoil factor 1 (TFF1) gene by estrogen receptor alpha.
Biochemical and biophysical research communications Apr, 2012 | Pubmed ID: 22382029
The role of histone chaperones in osteoblastic differentiation of C2C12 myoblasts.
Biochemical and biophysical research communications Jul, 2012 | Pubmed ID: 22705305
Protein L-isoaspartyl methyltransferase regulates p53 activity.
Nature communications Jun, 2012 | Pubmed ID: 22735455
PRMT6 overexpression upregulates TSP-1 and downregulates MMPs: its implication in motility and invasion.
Biochemical and biophysical research communications Mar, 2013 | Pubmed ID: 23380452
Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3.
Nucleic acids research May, 2013 | Pubmed ID: 23563152
DNA microarray profiling of genes differentially regulated by three heterochromatin protein 1 (HP1) homologs in Drosophila.
Biochemical and biophysical research communications May, 2013 | Pubmed ID: 23611785
Destabilization of TNF-α mRNA by Rapamycin.
Biomolecules & therapeutics Jan, 2012 | Pubmed ID: 24116273
Reversine induces multipotency of lineage-committed cells through epigenetic silencing of miR-133a.
Biochemical and biophysical research communications Feb, 2014 | Pubmed ID: 24513286
The role of tumor suppressor menin in IL-6 regulation in mouse islet tumor cells.
Biochemical and biophysical research communications Aug, 2014 | Pubmed ID: 25088994
HP1β suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2.
International journal of oncology Dec, 2014 | Pubmed ID: 25201136
Epigenetic activation of the Foxa2 gene is required for maintaining the potential of neural precursor cells to differentiate into dopaminergic neurons after expansion.
Stem cells and development Feb, 2015 | Pubmed ID: 25233056
Identification of small molecules that inhibit the histone chaperone Asf1 and its chromatin function.
BMB reports Dec, 2015 | Pubmed ID: 26058396
Syntaxin 4 regulates the surface localization of a promyogenic receptor Cdo thereby promoting myogenic differentiation.
Skeletal muscle , 2015 | Pubmed ID: 26347807
JQ1, an inhibitor of the epigenetic reader BRD4, suppresses the bidirectional MYC-AP4 axis via multiple mechanisms.
Oncology reports Feb, 2016 | Pubmed ID: 26573731
Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer.
Oncotarget May, 2016 | Pubmed ID: 27081696
S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis.
Molecular cell May, 2016 | Pubmed ID: 27151441
Patent cliff and strategic switch: exploring strategic design possibilities in the pharmaceutical industry.
SpringerPlus , 2016 | Pubmed ID: 27347468
Epigenetic role of nuclear S6K1 in early adipogenesis.
BMB reports Aug, 2016 | Pubmed ID: 27439608
Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch.
Experimental & molecular medicine Aug, 2016 | Pubmed ID: 27515126
Mapping the Technological Knowledge Landscape: The Case of Epigenetics.
Recent patents on anti-cancer drug discovery , 2016 | Pubmed ID: 27557814
PKN2 and Cdo interact to activate AKT and promote myoblast differentiation.
Cell death & disease Oct, 2016 | Pubmed ID: 27763641
A new manufacturing process to remove thrombogenic factors (II, VII, IX, X, and XI) from intravenous immunoglobulin gamma preparations.
Biologicals : journal of the International Association of Biological Standardization Jan, 2017 | Pubmed ID: 27876270
Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2017 | Pubmed ID: 28432138
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados