Department of Pediatric Dentistry,
Ninth People's Hospital,
Shanghai Jiaotong University School of Medicine,
Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology,
Department of Pediatric Dentistry, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology
Xiaowen Liu is an associate professor of bioinformatics in the Department of BioHealth Informatics, Indiana University-Purdue University Indianapolis (IUPUI). He received his bachelor’s and master’s degrees in computer science from Shandong University, China and obtained his PhD degree in computer science from the City University of Hong Kong. Before joining IUPUI, he worked as a postdoctoral fellow at the University of Western Ontario, the University of Waterloo, and the University of California, San Diego, from 2008 to 2012. His research focuses on computational proteomics, especially top-down proteomics, which is capable of identifying various proteoforms in biological samples. His lab has developed powerful software tools for top-down mass spectrometry-based proteoform identification, characterization, and quantitation, which have been widely used in the proteomics community.
A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch.
American journal of physiology. Heart and circulatory physiology Jul, 2009 | Pubmed ID: 19429823
Effect of spiral flow on the transport of oxygen in the aorta: a numerical study.
Annals of biomedical engineering Mar, 2010 | Pubmed ID: 20033776
Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta.
Journal of biomechanics Apr, 2011 | Pubmed ID: 21310418
Effect of the endothelial glycocalyx layer on arterial LDL transport under normal and high pressure.
Journal of theoretical biology Aug, 2011 | Pubmed ID: 21645523
Mechanotransduction of flow-induced shear stress by endothelial glycocalyx fibers is torque determined.
ASAIO journal (American Society for Artificial Internal Organs : 1992) Nov-Dec, 2011 | Pubmed ID: 21989421
Nitric oxide transport in an axisymmetric stenosis.
Journal of the Royal Society, Interface Oct, 2012 | Pubmed ID: 22593099
A survey on gas sensing technology.
Sensors (Basel, Switzerland) , 2012 | Pubmed ID: 23012563
Numerical simulation of nucleotide transport in the human thoracic aorta.
Journal of biomechanics Feb, 2013 | Pubmed ID: 23182905
The accelerated atherogenesis of venous grafts might be attributed to aggravated concentration polarization of low density lipoproteins: a numerical study.
Journal of biomechanics Sep, 2013 | Pubmed ID: 23972425
Enhanced accumulation of LDLs within the venous graft wall induced by elevated filtration rate may account for its accelerated atherogenesis.
Atherosclerosis Sep, 2014 | Pubmed ID: 25075936
Physiological significance of helical flow in the arterial system and its potential clinical applications.
Annals of biomedical engineering Jan, 2015 | Pubmed ID: 25169424
Nitric oxide transport in normal human thoracic aorta: effects of hemodynamics and nitric oxide scavengers.
PloS one , 2014 | Pubmed ID: 25405341
Simulation of contrast agent transport in arteries with multilayer arterial wall: impact of arterial transmural transport on the bolus delay and dispersion.
TheScientificWorldJournal , 2014 | Pubmed ID: 25692178
Effects of endothelium, stent design and deployment on the nitric oxide transport in stented artery: a potential role in stent restenosis and thrombosis.
Medical & biological engineering & computing May, 2015 | Pubmed ID: 25715753
Hemodynamic insight into overlapping bare-metal stents strategy in the treatment of aortic aneurysm.
Journal of biomechanics Jul, 2015 | Pubmed ID: 25911250
Does lower limb exercise worsen renal artery hemodynamics in patients with abdominal aortic aneurysm?
PloS one , 2015 | Pubmed ID: 25946196
Influence of proximal drug eluting stent (DES) on distal bare metal stent (BMS) in multi-stent implantation strategies in coronary arteries.
Medical engineering & physics Sep, 2015 | Pubmed ID: 26149391
Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study.
Artificial organs Jul, 2016 | Pubmed ID: 26581476
Influence of catheter insertion on the hemodynamic environment in coronary arteries.
Medical engineering & physics 09, 2016 | Pubmed ID: 27394085
Beamforming Based Full-Duplex for Millimeter-Wave Communication.
Sensors (Basel, Switzerland) Jul, 2016 | Pubmed ID: 27455256
Bioinspired helical graft with taper to enhance helical flow.
Journal of biomechanics 11, 2016 | Pubmed ID: 27745696
Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA).
Biomedical engineering online Dec, 2016 | Pubmed ID: 28155691
Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway.
Scientific reports 02, 2017 | Pubmed ID: 28191820
Numerical simulation of haemodynamics and low-density lipoprotein transport in the rabbit aorta and their correlation with atherosclerotic plaque thickness.
Journal of the Royal Society, Interface 04, 2017 | Pubmed ID: 28424305
Extrusion Bioprinting of Shear-Thinning Gelatin Methacryloyl Bioinks.
Advanced healthcare materials Jun, 2017 | Pubmed ID: 28464555
Transcatheter aortic valve replacement in patients with high aortic anguation.
Journal of thoracic disease May, 2017 | Pubmed ID: 28616338
Effect of longitudinal anatomical mismatch of stenting on the mechanical environment in human carotid artery with atherosclerotic plaques.
Medical engineering & physics 10, 2017 | Pubmed ID: 28826570
Thermoresponsive Mobile Interfaces with Switchable Wettability, Optical Properties, and Penetrability.
ACS applied materials & interfaces Oct, 2017 | Pubmed ID: 28945340
Blood-Vessel-on-a-Chip Platforms for Evaluating Nanoparticle Drug Delivery Systems.
Current drug metabolism , 2018 | Pubmed ID: 28952434
What is needed to make low-density lipoprotein transport in human aorta computational models suitable to explore links to atherosclerosis? Impact of initial and inflow boundary conditions.
Journal of biomechanics 02, 2018 | Pubmed ID: 29276068
[An optical coherent imaging system for measuring the strain of blood vessels].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi Oct, 2017 | Pubmed ID: 29761965
A General Strategy for Extrusion Bioprinting of Bio-Macromolecular Bioinks through Alginate-Templated Dual-Stage Crosslinking.
Macromolecular bioscience Sep, 2018 | Pubmed ID: 29943499
Cancer Cell Glycocalyx and Its Significance in Cancer Progression.
International journal of molecular sciences Aug, 2018 | Pubmed ID: 30135409
Digitally Tunable Microfluidic Bioprinting of Multilayered Cannular Tissues.
Advanced materials (Deerfield Beach, Fla.) Oct, 2018 | Pubmed ID: 30136318
Hydraulic conductivity and low-density lipoprotein transport of the venous graft wall in an arterial bypass.
Biomedical engineering online Apr, 2019 | Pubmed ID: 31023303
3D Bioprinting: from Benches to Translational Applications.
Small (Weinheim an der Bergstrasse, Germany) 06, 2019 | Pubmed ID: 31033203
Transfer of Low-Density Lipoproteins in Coronary Artery Bifurcation Lesions with Stenosed Side Branch: Numerical Study.
Computational and mathematical methods in medicine , 2019 | Pubmed ID: 31737085
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation.
Autophagy Feb, 2020 | Pubmed ID: 32019420
Influence of Artery Straightening on Local Hemodynamics in Left Anterior Descending (LAD) Artery after Stent Implantation.
Cardiology research and practice , 2020 | Pubmed ID: 32550022
Bioinspired Multiresonant Acoustic Devices Based on Electrospun Piezoelectric Polymeric Nanofibers.
ACS applied materials & interfaces Aug, 2020 | Pubmed ID: 32639712
Spatiotemporal transfer of nitric oxide in patient-specific atherosclerotic carotid artery bifurcations with MRI and computational fluid dynamics modeling.
Computers in biology and medicine 10, 2020 | Pubmed ID: 33035961
Magnesium-Based Whitlockite Bone Mineral Promotes Neural and Osteogenic Activities.
ACS biomaterials science & engineering 10, 2020 | Pubmed ID: 33320584
Flow shear stress controls the initiation of neovascularization via heparan sulfate proteoglycans within a biomimetic microfluidic model.
Lab on a chip 01, 2021 | Pubmed ID: 33351007
Numerical analysis of the hemodynamics of rat aorta based on magnetic resonance imaging and fluid-structure interaction.
International journal for numerical methods in biomedical engineering Mar, 2021 | Pubmed ID: 33750033
Flow-mediated dilation analysis coupled with nitric oxide transport to enhance the assessment of endothelial function.
Journal of applied physiology (Bethesda, Md. : 1985) Apr, 2021 | Pubmed ID: 33830813
Qinggang Dai*,1,
Yujiao Han*,2,
Furong Xie*,1,
Xuhui Ma3,
Zhan Xu2,
Xiao Liu1,
Weiguo Zou2,
Jun Wang1
1Department of Pediatric Dentistry, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research Center of Stomatology,
2State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences,
3Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
Ping Zhao1,
Xing Zhang1,
Xiao Liu1,
Li Wang4,
Haoran Su1,
Liyi Wang1,
Dongrui Zhang1,
Xiaoyan Deng3,
Yubo Fan1,2
1Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University,
2School of Engineering Medicine, Beihang University,
3Artificial Intelligence Key Laboratory of Sichuan Province, School of Automation and Information Engineering, Sichuan University of Science and Engineering,
4, Beijing Research Center of Urban System Engineering
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados