Paul D. Robbins

NF-κB inhibition delays DNA damage-induced senescence and aging in mice.

Lim mineralization protein 3 induces the osteogenic differentiation of human amniotic fluid stromal cells through Kruppel-like factor-4 downregulation and further bone-specific gene expression.

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death.

Regulation of immune responses by extracellular vesicles.

NF-κB activation with aging: characterization and therapeutic inhibition.

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

IL-Y, a synthetic member of the IL-12 cytokine family, suppresses the development of type 1 diabetes in NOD mice.

Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function.

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.

Regulation of chronic inflammatory and immune processes by extracellular vesicles.

Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms.

Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses.

mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.

Quantitative Analysis of Cellular Senescence in Culture and In Vivo.

Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism.

Cellular senescence mediates fibrotic pulmonary disease.

New agents that target senescent cells: the flavone, fisetin, and the BCL-X inhibitors, A1331852 and A1155463.

Systems biology guided by XCMS Online metabolomics.

ADAMTS5 Deficiency Protects Mice From Chronic Tobacco Smoking-induced Intervertebral Disc Degeneration.

Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2 Scripps Symposium on the Biology of Aging.

Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice.

Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes.

Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype.

The Clinical Potential of Senolytic Drugs.

Identification of HSP90 inhibitors as a novel class of senolytics.

Gene Delivery to Joints by Intra-Articular Injection.

Circulating levels of monocyte chemoattractant protein-1 as a potential measure of biological age in mice and frailty in humans.

Arthritis Gene Therapy Approved in Korea.

Extracellular vesicles and aging.

Senotherapeutics for healthy ageing.

Arthritis gene therapy is becoming a reality.

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

Treating Age-Related Diseases with Somatic Stem Cells.

Hsp90 inhibitors as senolytic drugs to extend healthy aging.

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Nuclear Genomic Instability and Aging.

Senolytics improve physical function and increase lifespan in old age.

Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging.

Fisetin is a senotherapeutic that extends health and lifespan.

Mouse Models of Accelerated Cellular Senescence.

Methods to Quantify the NF-κB Pathway During Senescence.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Measuring biological age in mice using differential mass spectrometry.

Murine models of accelerated aging and musculoskeletal disease.

Signal Transduction, Ageing and Disease.

Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.