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Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.
Molecular cancer research : MCR May, 2010 | Pubmed ID: 20407015
The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound.
PloS one Apr, 2010 | Pubmed ID: 20422012
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
Molecular cancer research : MCR Mar, 2011 | Pubmed ID: 21343334
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.
DNA repair Aug, 2011 | Pubmed ID: 21676659
Contribution of yeast and plant research for improving human health.
Journal of biomedicine & biotechnology , 2012 | Pubmed ID: 22851885
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.
Nucleic acids research Jan, 2013 | Pubmed ID: 23161690
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics.
Cell cycle (Georgetown, Tex.) Apr, 2013 | Pubmed ID: 23518503
P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.
PloS one , 2013 | Pubmed ID: 23861960
Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code.
Nucleic acids research Oct, 2013 | Pubmed ID: 23892287
Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: clarifying the role of N3-methyladenine.
Mutation research Jan, 2014 | Pubmed ID: 24211855
Identification of new p53 target microRNAs by bioinformatics and functional analysis.
BMC cancer Nov, 2013 | Pubmed ID: 24256616
A cross-platform comparison of affymetrix and Agilent microarrays reveals discordant miRNA expression in lung tumors of c-Raf transgenic mice.
PloS one , 2013 | Pubmed ID: 24265725
Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease.
PloS one , 2013 | Pubmed ID: 24376681
TP53 mutants in the tower of babel of cancer progression.
Human mutation Jun, 2014 | Pubmed ID: 24449472
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.
Oncotarget Apr, 2014 | Pubmed ID: 24926492
Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jan, 2015 | Pubmed ID: 25312347
Cooperative interactions between p53 and NFκB enhance cell plasticity.
Oncotarget Dec, 2014 | Pubmed ID: 25401416
Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay.
PloS one , 2015 | Pubmed ID: 25668429
In-silico identification and functional validation of allele-dependent AR enhancers.
Oncotarget Mar, 2015 | Pubmed ID: 25693204
Whole-genome cartography of p53 response elements ranked on transactivation potential.
BMC genomics Jun, 2015 | Pubmed ID: 26081755
Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay.
PloS one , 2015 | Pubmed ID: 26147604
RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes.
Nucleic acids research Dec, 2015 | Pubmed ID: 26240374
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas.
Oncotarget Oct, 2015 | Pubmed ID: 26427040
Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction.
Life sciences Dec, 2015 | Pubmed ID: 26475964
The 5'-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding.
Oncotarget Nov, 2015 | Pubmed ID: 26498684
The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma.
Pigment cell & melanoma research Mar, 2016 | Pubmed ID: 26581427
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.
Oncotarget Jan, 2016 | Pubmed ID: 26735173
The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer.
Cancer research 05, 2016 | Pubmed ID: 27197265
c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma.
Oncotarget Oct, 2016 | Pubmed ID: 27602772
Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.
FEMS yeast research 11, 2016 | Pubmed ID: 27683095
The structure formed by inverted repeats in p53 response elements determines the transactivation activity of p53 protein.
Biochemical and biophysical research communications 01, 2017 | Pubmed ID: 28007599
DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties.
Molecular oncology 06, 2017 | Pubmed ID: 28296148
Inherited determinants of early recurrent somatic mutations in prostate cancer.
Nature communications 06, 2017 | Pubmed ID: 28663546
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity.
Genome research 10, 2017 | Pubmed ID: 28904012
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Nature biotechnology 03, 2018 | Pubmed ID: 29431739
Synthesis of 2,6-Diamino-Substituted Purine Derivatives and Evaluation of Cell Cycle Arrest in Breast and Colorectal Cancer Cells.
Molecules (Basel, Switzerland) Aug, 2018 | Pubmed ID: 30103421
Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in 53-deficient cancer cells.
Cell division , 2018 | Pubmed ID: 30603043
LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β.
Nature communications 04, 2019 | Pubmed ID: 31036808
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