Department of Molecular and Cellular Biology
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Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells.
Nature biotechnology May, 2002 | Pubmed ID: 11981565
Functional siRNA expression from transfected PCR products.
RNA (New York, N.Y.) Nov, 2002 | Pubmed ID: 12458798
Small interfering RNAs expressed from a Pol III promoter suppress the EWS/Fli-1 transcript in an Ewing sarcoma cell line.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2003 | Pubmed ID: 12788655
Amplification of RNAi--targeting HLA mRNAs.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2005 | Pubmed ID: 15851019
Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2005 | Pubmed ID: 15963934
Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro.
Nature biotechnology May, 2006 | Pubmed ID: 16648841
RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy.
Annals of the New York Academy of Sciences Oct, 2006 | Pubmed ID: 17145937
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC.
Nucleic acids research , 2007 | Pubmed ID: 17660190
Cloning and detecting signature microRNAs from mammalian cells.
Methods in enzymology , 2007 | Pubmed ID: 17720482
Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2008 | Pubmed ID: 17726454
Use of a U16 snoRNA-containing ribozyme library to identify ribozyme targets in HIV-1.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2008 | Pubmed ID: 18388915
Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy.
Molecular therapy : the journal of the American Society of Gene Therapy Aug, 2008 | Pubmed ID: 18461053
Functional and intracellular localization properties of U6 promoter-expressed siRNAs, shRNAs, and chimeric VA1 shRNAs in mammalian cells.
RNA (New York, N.Y.) Sep, 2008 | Pubmed ID: 18697923
Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells.
Nucleic acids research May, 2009 | Pubmed ID: 19304999
SNPs in human miRNA genes affect biogenesis and function.
RNA (New York, N.Y.) Sep, 2009 | Pubmed ID: 19617315
Sequence context outside the target region influences the effectiveness of miR-223 target sites in the RhoB 3'UTR.
Nucleic acids research Jan, 2010 | Pubmed ID: 19850724
Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV coreceptor CCR5.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2010 | Pubmed ID: 20104214
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma.
Science translational medicine Jun, 2010 | Pubmed ID: 20555022
An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice.
Science translational medicine Jan, 2011 | Pubmed ID: 21248316
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2011 | Pubmed ID: 21952167
Interplay between HIV-1 infection and host microRNAs.
Nucleic acids research Nov, 2011 | Pubmed ID: 22080513
The role of antisense long noncoding RNA in small RNA-triggered gene activation.
RNA (New York, N.Y.) Dec, 2014 | Pubmed ID: 25344398
Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy.
Nucleic acids research Jan, 2018 | Pubmed ID: 29077949
HIV Replication and Latency in a Humanized NSG Mouse Model during Suppressive Oral Combinational Antiretroviral Therapy.
Journal of virology 04, 2018 | Pubmed ID: 29343582
Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1.
Theranostics , 2018 | Pubmed ID: 29556342
Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles.
AIDS research and human retroviruses 11, 2018 | Pubmed ID: 29804468
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