David H. Wasserman

Prior exercise and the response to insulin-induced hypoglycemia in the dog.

Prevention of overt hypoglycemia during exercise: stimulation of endogenous glucose production independent of hepatic catecholamine action and changes in pancreatic hormone concentration.

Contrasting effects of exercise and NOS inhibition on tissue-specific fatty acid and glucose uptake in mice.

Transporter-mediated absorption is the primary route of entry and is required for passive absorption of intestinal glucose into the blood of conscious dogs.

Fiber type-specific determinants of Vmax for insulin-stimulated muscle glucose uptake in vivo.

Prior exercise enhances passive absorption of intraduodenal glucose.

Effect of antecedent hypoglycemia on counterregulatory responses to subsequent euglycemic exercise in type 1 diabetes.

Hexokinase II partial knockout impairs exercise-stimulated glucose uptake in oxidative muscles of mice.

Interaction of insulin and prior exercise in control of hepatic metabolism of a glucose load.

Regulation of hepatic and peripheral glucose disposal.

Distributed control of glucose uptake by working muscles of conscious mice: roles of transport and phosphorylation.

Quinides of roasted coffee enhance insulin action in conscious rats.

Suppression of endogenous glucose production by mild hyperinsulinemia during exercise is determined predominantly by portal venous insulin.

Hexokinase II overexpression improves exercise-stimulated but not insulin-stimulated muscle glucose uptake in high-fat-fed C57BL/6J mice.

Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1.

Effect of sex on counterregulatory responses to exercise after antecedent hypoglycemia in type 1 diabetes.

Hepatic glucose autoregulation: responses to small, non-insulin-induced changes in arterial glucose.

AMP kinase-induced skeletal muscle glucose but not long-chain fatty acid uptake is dependent on nitric oxide.

AMPK stimulation increases LCFA but not glucose clearance in cardiac muscle in vivo.

Regulation of insulin-stimulated muscle glucose uptake in the conscious mouse: role of glucose transport is dependent on glucose phosphorylation capacity.

Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis.

Portal venous hyperinsulinemia does not stimulate gut glucose absorption in the conscious dog.

Physical activity/exercise and type 2 diabetes.

Heart-type fatty acid-binding protein reciprocally regulates glucose and fatty acid utilization during exercise.

Control of exercise-stimulated muscle glucose uptake by GLUT4 is dependent on glucose phosphorylation capacity in the conscious mouse.

Portal vein caffeine infusion enhances net hepatic glucose uptake during a glucose load in conscious dogs.

Exercise-induced changes in insulin and glucagon are not required for enhanced hepatic glucose uptake after exercise but influence the fate of glucose within the liver.

Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice.

Glucoregulation during and after exercise in health and insulin-dependent diabetes.

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside causes acute hepatic insulin resistance in vivo.

Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output.

Interaction of physiological mechanisms in control of muscle glucose uptake.

Hexokinase II protein content is a determinant of exercise endurance capacity in the mouse.

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside renders glucose output by the liver of the dog insensitive to a pharmacological increment in insulin.

Mobilization of glucose from the liver during exercise and replenishment afterward.

Plasminogen activator inhibitor-1 modulates adipocyte differentiation.

Energy state of the liver during short-term and exhaustive exercise in C57BL/6J mice.

Insulin secretion in the conscious mouse is biphasic and pulsatile.

Partial gene deletion of heart-type fatty acid-binding protein limits the severity of dietary-induced insulin resistance.

Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo?

Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse.

Physical activity/exercise and type 2 diabetes: a consensus statement from the American Diabetes Association.

Point-Counterpoint: Glucose phosphorylation is/is not a significant barrier to muscle glucose uptake by the working muscle.

Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice.

Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter.

Phosphorylation barriers to skeletal and cardiac muscle glucose uptakes in high-fat fed mice: studies in mice with a 50% reduction of hexokinase II.

Insulin action in the double incretin receptor knockout mouse.

Glucose metabolism in vivo in four commonly used inbred mouse strains.

Long chain fatty acid uptake in vivo: comparison of [125I]-BMIPP and [3H]-bromopalmitate.

Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c.

Metabolic implications of reduced heart-type fatty acid binding protein in insulin resistant cardiac muscle.

Four grams of glucose.

The glucagon-like peptide-1 receptor regulates endogenous glucose production and muscle glucose uptake independent of its incretin action.

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.

Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity.

Skeletal muscle AMP-activated protein kinase is essential for the metabolic response to exercise in vivo.

NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse.

Hepatic energy state is regulated by glucagon receptor signaling in mice.

Lost in translation.

Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2.

Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo.

Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARalpha and FGF21 transcripts in vivo.

Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistance.

Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice.

The physiological regulation of glucose flux into muscle in vivo.

Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking.

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.

Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice.

Assessment of different bariatric surgeries in the treatment of obesity and insulin resistance in mice.

Hepatic glucagon action is essential for exercise-induced reversal of mouse fatty liver.

Mesenchymal stem cell transplantation for the infarcted heart: a role in minimizing abnormalities in cardiac-specific energy metabolism.

Overproduction of angiotensinogen from adipose tissue induces adipose inflammation, glucose intolerance, and insulin resistance.

Disassociation of Muscle Insulin Signaling and Insulin-Stimulated Glucose Uptake during Endotoxemia.