Johns Hopkins Malaria Research Institute
Marcelo Jacobs-Lorena has not added Biography.
If you are Marcelo Jacobs-Lorena and would like to personalize this page please email our Author Liaison for assistance.
An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2005 | Pubmed ID: 16260729
Insight into a conserved lifestyle: protein-carbohydrate adhesion strategies of vector-borne pathogens.
Infection and immunity Dec, 2005 | Pubmed ID: 16299269
Entomopathogenic fungi as biological insecticides to control malaria.
Trends in parasitology Feb, 2006 | Pubmed ID: 16377249
Identification of the Aedes aegypti peritrophic matrix protein AeIMUCI as a heme-binding protein.
Biochemistry Aug, 2006 | Pubmed ID: 16878988
Disruption of Plasmodium falciparum development by antibodies against a conserved mosquito midgut antigen.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2007 | Pubmed ID: 17673553
Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17873063
Flipping the paradigm on malaria transmission-blocking vaccines.
Trends in parasitology Aug, 2008 | Pubmed ID: 18599352
Anopheles gambiae Croquemort SCRBQ2, expression profile in the mosquito and its potential interaction with the malaria parasite Plasmodium berghei.
Insect biochemistry and molecular biology May-Jun, 2009 | Pubmed ID: 19366631
Plasmodium sporozoite invasion of the mosquito salivary gland.
Current opinion in microbiology Aug, 2009 | Pubmed ID: 19608457
Surface-expressed enolases of Plasmodium and other pathogens.
Memorias do Instituto Oswaldo Cruz Aug, 2011 | Pubmed ID: 21881761
Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2011 | Pubmed ID: 21949403
Fighting malaria with engineered symbiotic bacteria from vector mosquitoes.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22802646
Regulation of anti-Plasmodium immunity by a LITAF-like transcription factor in the malaria vector Anopheles gambiae.
PLoS pathogens , 2012 | Pubmed ID: 23093936
Genetic approaches to interfere with malaria transmission by vector mosquitoes.
Trends in biotechnology Mar, 2013 | Pubmed ID: 23395485
Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23572579
Enterobacter-activated mosquito immune responses to Plasmodium involve activation of SRPN6 in Anopheles stephensi.
PloS one , 2013 | Pubmed ID: 23658788
-Mosquito Interactions: A Tale of Roadblocks and Detours.
Advances in insect physiology , 2010 | Pubmed ID: 23729903
Transgenic mosquitoes expressing a phospholipase A(2) gene have a fitness advantage when fed Plasmodium falciparum-infected blood.
PloS one , 2013 | Pubmed ID: 24098427
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector.
Memorias do Instituto Oswaldo Cruz Aug, 2014 | Pubmed ID: 25185005
Malaria parasite Pfs47 disrupts JNK signaling to escape mosquito immunity.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2015 | Pubmed ID: 25617364
Hemocyte differentiation mediates the mosquito late-phase immune response against Plasmodium in Anopheles gambiae.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2015 | Pubmed ID: 26080400
Genetic Control Of Malaria Mosquitoes.
Trends in parasitology Mar, 2016 | Pubmed ID: 26809567
Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites.
Malaria journal Aug, 2016 | Pubmed ID: 27480269
Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion.
The Journal of experimental medicine 09, 2016 | Pubmed ID: 27551151
Confers Survival upon Amino Acid Starvation.
mBio 03, 2017 | Pubmed ID: 28351924
Driving mosquito refractoriness to with engineered symbiotic bacteria.
Science (New York, N.Y.) 09, 2017 | Pubmed ID: 28963255
Field assessment of potential sugar feeding stations for disseminating bacteria in a paratransgenic approach to control malaria.
Malaria journal Oct, 2018 | Pubmed ID: 30333029
Identification of GAPDH epitopes for generation of antibodies that inhibit malaria infection.
Life science alliance Oct, 2018 | Pubmed ID: 30456380
CXCR4 regulates development in mouse and human hepatocytes.
The Journal of experimental medicine 08, 2019 | Pubmed ID: 31189656
Mosquito Microbiota and Implications for Disease Control.
Trends in parasitology 02, 2020 | Pubmed ID: 31866183
A key fits a mosquito lock.
Proceedings of the National Academy of Sciences of the United States of America 02, 2020 | Pubmed ID: 32024758
Transcriptional profiling and physiological roles of Aedes aegypti spermathecal-related genes.
BMC genomics Feb, 2020 | Pubmed ID: 32041546
Use of Microbiota to Fight Mosquito-Borne Disease.
Frontiers in genetics , 2020 | Pubmed ID: 32211030
The response of Plasmodium falciparum to isoleucine withdrawal is dependent on the stage of progression through the intraerythrocytic cell cycle.
Malaria journal Apr, 2020 | Pubmed ID: 32268910
Self-limiting paratransgenesis.
PLoS neglected tropical diseases 08, 2020 | Pubmed ID: 32810151
Clock genes and environmental cues coordinate pheromone synthesis, swarming, and mating.
Science (New York, N.Y.) 01, 2021 | Pubmed ID: 33479155
The fibrinolytic system enables the onset of infection in the mosquito vector and the mammalian host.
Science advances Feb, 2021 | Pubmed ID: 33547079
A Genetically Modified Anti-Plasmodium Bacterium Is Harmless to the Foragers of the Stingless Bee Partamona helleri.
Microbial ecology Jul, 2021 | Pubmed ID: 34231036
Plasmodium sporozoite phospholipid scramblase interacts with mammalian carbamoyl-phosphate synthetase 1 to infect hepatocytes.
Nature communications 11, 2021 | Pubmed ID: 34799567
Identification of Key Determinants of Cerebral Malaria Development and Inhibition Pathways.
mBio Jan, 2022 | Pubmed ID: 35073748
Mabel Taracena1,2,
Catherine Hunt1,
Pamela Pennington3,
Deborah Andrew4,5,
Marcelo Jacobs-Lorena5,6,
Ellen Dotson1,
Michael Wells5,7,8
1Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention,
2Department of Entomology, Cornell University,
3Centro de Estudios en Biotecnologia, Universidad del Valle de Guatemala,
4Department of Cell Biology, Johns Hopkins School of Medicine,
5Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health,
6Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute,
7Department of Cell Biology, Johns Hopkins School of Medicine,
8Biomedical Sciences Department, Idaho College of Osteopathic Medicine
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados