Todd D. Gould

Endophenotypes in bipolar disorder.

Signaling networks in the pathophysiology and treatment of mood disorders.

The Wnt signaling pathway in bipolar disorder.

Post-mortem interval effects on the phosphorylation of signaling proteins.

The endophenotype concept in psychiatry: etymology and strategic intentions.

Effects of a glycogen synthase kinase-3 inhibitor, lithium, in adenomatous polyposis coli mutant mice.

The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.

Signal transduction and genes-to-behaviors pathways in psychiatric diseases.

Glycogen synthase kinase-3: a target for novel bipolar disorder treatments.

The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry.

Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test.

Molecular effects of lithium.

DARPP-32: A molecular switch at the nexus of reward pathway plasticity.

Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs.

Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics.

Toward constructing an endophenotype strategy for bipolar disorders.

Targeting glycogen synthase kinase-3 as an approach to develop novel mood-stabilising medications.

Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders.

Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium.

Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors.

Performance on a virtual reality spatial memory navigation task in depressed patients.

Targeting signal transduction pathways in the treatment of mood disorders: recent insights into the relevance of the Wnt pathway.

The behavioral actions of lithium in rodent models: leads to develop novel therapeutics.

Animal models of bipolar disorder and mood stabilizer efficacy: a critical need for improvement.

Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.

Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice.

Lithium's antisuicidal efficacy: elucidation of neurobiological targets using endophenotype strategies.

Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents.

Shock-induced aggression in mice is modified by lithium.

Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans.

Advances in multidisciplinary and cross-species approaches to examine the neurobiology of psychiatric disorders.

Affect-related behaviors in mice selectively bred for high and low voluntary alcohol consumption.

Differential lithium efficacy in reducing suicidal behaviors compared with suicidal thoughts.