PulmoScience Laboratory,
Department of Pulmonology,
PulmoScience Laboratory, Department of Pulmonology
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World Congress on Lung Health and 10th ERS Annual Congress 30 August-3 September 2000, Florence, Italy.
Respiratory research , 2000 | Pubmed ID: 11667983
Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells.
Immunology Aug, 2002 | Pubmed ID: 12153515
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
The Journal of clinical investigation Jun, 2003 | Pubmed ID: 12782669
Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro.
American journal of respiratory cell and molecular biology Feb, 2004 | Pubmed ID: 12871849
Are rhinovirus-induced airway responses in asthma aggravated by chronic allergen exposure?
American journal of respiratory and critical care medicine Nov, 2003 | Pubmed ID: 12893645
Rhinovirus increases human beta-defensin-2 and -3 mRNA expression in cultured bronchial epithelial cells.
FEMS immunology and medical microbiology Aug, 2003 | Pubmed ID: 12900056
Series introduction: Innate host defense of the respiratory epithelium.
Journal of leukocyte biology Jan, 2004 | Pubmed ID: 14612432
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2003 | Pubmed ID: 14662872
Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stress.
Free radical biology & medicine Mar, 2004 | Pubmed ID: 14990357
Bacterial products increase expression of the human cathelicidin hCAP-18/LL-37 in cultured human sinus epithelial cells.
FEMS immunology and medical microbiology Oct, 2004 | Pubmed ID: 15364108
TGF-beta differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells.
The Journal of allergy and clinical immunology Oct, 2004 | Pubmed ID: 15480317
Interactions between neutrophil-derived antimicrobial peptides and airway epithelial cells.
Journal of leukocyte biology Apr, 2005 | Pubmed ID: 15591123
Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense.
Physiological genomics May, 2005 | Pubmed ID: 15701729
Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge.
The Journal of allergy and clinical immunology Apr, 2005 | Pubmed ID: 15805998
The human cathelicidin LL-37: a multifunctional peptide involved in infection and inflammation in the lung.
Pulmonary pharmacology & therapeutics , 2005 | Pubmed ID: 15939310
Host defense effector molecules in mucosal secretions.
FEMS immunology and medical microbiology Aug, 2005 | Pubmed ID: 16051067
Bronchial CD8 cell infiltrate and lung function decline in asthma.
American journal of respiratory and critical care medicine Oct, 2005 | Pubmed ID: 16085937
Cytokine-dependent proliferation of human CD34+ progenitor cells in the absence of serum is suppressed by their progeny's production of serine proteinases.
Stem cells (Dayton, Ohio) Feb, 2006 | Pubmed ID: 16109763
Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application.
Peptides Apr, 2006 | Pubmed ID: 16274847
Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione.
Respiratory research Nov, 2005 | Pubmed ID: 16309548
Expression of epidermal growth factors and their receptors in the bronchial epithelium of subjects with chronic obstructive pulmonary disease.
American journal of clinical pathology Feb, 2006 | Pubmed ID: 16393673
A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes.
BMC genomics Jan, 2006 | Pubmed ID: 16420688
Human cathelicidin LL-37 is a chemoattractant for eosinophils and neutrophils that acts via formyl-peptide receptors.
International archives of allergy and immunology , 2006 | Pubmed ID: 16557028
Epithelial differentiation is a determinant in the production of eotaxin-2 and -3 by bronchial epithelial cells in response to IL-4 and IL-13.
Molecular immunology Feb, 2007 | Pubmed ID: 16740309
The antimicrobial peptide LL-37 enhances IL-8 release by human airway smooth muscle cells.
The Journal of allergy and clinical immunology Jun, 2006 | Pubmed ID: 16750994
The SERPINE2 gene and chronic obstructive pulmonary disease.
American journal of human genetics Jul, 2006 | Pubmed ID: 16773582
Exploring host-pathogen interactions at the epithelial surface: application of transcriptomics in lung biology.
American journal of physiology. Lung cellular and molecular physiology Feb, 2007 | Pubmed ID: 17041013
Adenovirus-specific CD4+ T cell clones recognizing endogenous antigen inhibit viral replication in vitro through cognate interaction.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2006 | Pubmed ID: 17142788
Small airways dysfunction and neutrophilic inflammation in bronchial biopsies and BAL in COPD.
Chest Jan, 2007 | Pubmed ID: 17218556
Demonstration of bacterial cells and glycocalyx in biofilms on human tonsils.
Archives of otolaryngology--head & neck surgery Feb, 2007 | Pubmed ID: 17309977
Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine Jul, 2007 | Pubmed ID: 17379851
Inhaled nitric oxide attenuates pulmonary inflammation and fibrin deposition and prolongs survival in neonatal hyperoxic lung injury.
American journal of physiology. Lung cellular and molecular physiology Jul, 2007 | Pubmed ID: 17384081
Human neutrophil peptide-1 inhibits both the classical and the lectin pathway of complement activation.
Molecular immunology Jul, 2007 | Pubmed ID: 17448537
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD.
Thorax Dec, 2007 | Pubmed ID: 17573446
The role of epithelial beta-defensins and cathelicidins in host defense of the lung.
Experimental lung research Dec, 2007 | Pubmed ID: 18075828
An antimicrobial peptide modulates epithelial responses to bacterial products.
The Laryngoscope May, 2008 | Pubmed ID: 18300705
Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma.
The Journal of allergy and clinical immunology May, 2008 | Pubmed ID: 18405955
Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients.
Respiratory research Aug, 2009 | Pubmed ID: 19703285
Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trial.
Annals of internal medicine Oct, 2009 | Pubmed ID: 19841453
Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.
BMC medical genetics Jan, 2010 | Pubmed ID: 20078883
Expression patterns of protein C inhibitor in mouse development.
Journal of molecular histology Feb, 2010 | Pubmed ID: 20229239
Recent advances in alveolar biology: evolution and function of alveolar proteins.
Respiratory physiology & neurobiology Aug, 2010 | Pubmed ID: 20433956
Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.
Respiratory research May, 2010 | Pubmed ID: 20487524
LL-37 directs macrophage differentiation toward macrophages with a proinflammatory signature.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2010 | Pubmed ID: 20610648
Severe congenital neutropenia in a multigenerational family with a novel neutrophil elastase (ELANE) mutation.
Annals of hematology Feb, 2011 | Pubmed ID: 20803142
Pro-inflammatory mechanisms of muscarinic receptor stimulation in airway smooth muscle.
Respiratory research Sep, 2010 | Pubmed ID: 20875145
The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study.
BMC medical genetics Feb, 2011 | Pubmed ID: 21320324
Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD.
Respiratory research Mar, 2011 | Pubmed ID: 21426578
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides.
Respiratory research May, 2011 | Pubmed ID: 21529380
PRAME-specific Allo-HLA-restricted T cells with potent antitumor reactivity useful for therapeutic T-cell receptor gene transfer.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2011 | Pubmed ID: 21771875
Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice.
Atherosclerosis Feb, 2012 | Pubmed ID: 21798539
A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress.
Cell stress & chaperones Mar, 2012 | Pubmed ID: 22038282
α1-antitrypsin production by proinflammatory and antiinflammatory macrophages and dendritic cells.
American journal of respiratory cell and molecular biology May, 2012 | Pubmed ID: 22162908
Difference in symptom severity between early and late grass pollen season in patients with seasonal allergic rhinitis.
Clinical and translational allergy Dec, 2011 | Pubmed ID: 22410160
Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease.
PloS one , 2012 | Pubmed ID: 22952638
Profiling the proteome of exhaled breath condensate in healthy smokers and COPD patients by LC-MS/MS.
International journal of molecular sciences Oct, 2012 | Pubmed ID: 23203040
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice.
The Journal of nutritional biochemistry Aug, 2013 | Pubmed ID: 23337345
Systemic inflammation and lung function impairment in morbidly obese subjects with the metabolic syndrome.
Journal of obesity , 2013 | Pubmed ID: 23509614
CD8(+) T cells characterize early smoking-related airway pathology in patients with asthma.
Respiratory medicine Jul, 2013 | Pubmed ID: 23639272
Inhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trial.
PloS one , 2013 | Pubmed ID: 23667615
Development and validation of a 5-day-ahead hay fever forecast for patients with grass-pollen-induced allergic rhinitis.
International journal of biometeorology Aug, 2014 | Pubmed ID: 23780494
Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity.
Thorax Jan, 2014 | Pubmed ID: 23925644
Development of a nose cream containing the synthetic antimicrobial peptide P60.4Ac for eradication of methicillin-resistant Staphylococcus aureus carriage.
Journal of pharmaceutical sciences Oct, 2013 | Pubmed ID: 23955373
Increase in net activity of serine proteinases but not gelatinases after local endotoxin exposure in the peripheral airways of healthy subjects.
PloS one , 2013 | Pubmed ID: 24086430
Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin.
Human molecular genetics Feb, 2014 | Pubmed ID: 24097797
The effect of PPE-induced emphysema and chronic LPS-induced pulmonary inflammation on atherosclerosis development in APOE*3-LEIDEN mice.
PloS one , 2013 | Pubmed ID: 24303000
Recent progress in peptide vaccination in cancer with a focus on non-small-cell lung cancer.
Expert review of vaccines Jan, 2014 | Pubmed ID: 24308580
pH in exhaled breath condensate and nasal lavage as a biomarker of air pollution-related inflammation in street traffic-controllers and office-workers.
Clinics (Sao Paulo, Brazil) Dec, 2013 | Pubmed ID: 24473505
Steroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokers.
PloS one , 2014 | Pubmed ID: 24505290
Susceptibility to chronic mucus hypersecretion, a genome wide association study.
PloS one , 2014 | Pubmed ID: 24714607
LL-37-derived peptides eradicate multidrug-resistant Staphylococcus aureus from thermally wounded human skin equivalents.
Antimicrobial agents and chemotherapy Aug, 2014 | Pubmed ID: 24841266
Efficient and sensitive identification and quantification of airborne pollen using next-generation DNA sequencing.
Molecular ecology resources Jan, 2015 | Pubmed ID: 24893805
Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Nature genetics Jul, 2014 | Pubmed ID: 24929828
Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.
The European respiratory journal Jan, 2015 | Pubmed ID: 25234806
Club cells, CC10 and self-control at the epithelial surface.
The European respiratory journal Oct, 2014 | Pubmed ID: 25271220
Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.
The European respiratory journal Feb, 2015 | Pubmed ID: 25323228
Brown adipose tissue takes up plasma triglycerides mostly after lipolysis.
Journal of lipid research Jan, 2015 | Pubmed ID: 25351615
Reproducibility of exhaled nitric oxide measurements in overweight and obese adults.
BMC research notes Nov, 2014 | Pubmed ID: 25366981
Muscarinic M3 receptors on structural cells regulate cigarette smoke-induced neutrophilic airway inflammation in mice.
American journal of physiology. Lung cellular and molecular physiology Nov, 2014 | Pubmed ID: 25381025
Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease.
American journal of respiratory cell and molecular biology Aug, 2015 | Pubmed ID: 25514360
Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine Apr, 2015 | Pubmed ID: 25611785
The innate immune function of airway epithelial cells in inflammatory lung disease.
The European respiratory journal Apr, 2015 | Pubmed ID: 25700381
Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2015 | Pubmed ID: 25712218
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.
Nature communications Mar, 2015 | Pubmed ID: 25754609
Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD.
PloS one , 2015 | Pubmed ID: 25803709
Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma.
Thorax Jul, 2015 | Pubmed ID: 25934136
Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells.
Thorax Jul, 2015 | Pubmed ID: 25995156
Local and systemic XAGE-1b-specific immunity in patients with lung adenocarcinoma.
Cancer immunology, immunotherapy : CII Sep, 2015 | Pubmed ID: 26025564
Prevention of exacerbations in patients with COPD and vitamin D deficiency through vitamin D supplementation (PRECOVID): a study protocol.
BMC pulmonary medicine Sep, 2015 | Pubmed ID: 26399451
Therapeutic potential of soluble guanylate cyclase modulators in neonatal chronic lung disease.
American journal of physiology. Lung cellular and molecular physiology Nov, 2015 | Pubmed ID: 26432873
Antimicrobial Peptides and Innate Lung Defenses: Role in Infectious and Noninfectious Lung Diseases and Therapeutic Applications.
Chest Feb, 2016 | Pubmed ID: 26502035
Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)2 Vitamin D3 Treatment.
PloS one , 2015 | Pubmed ID: 26545199
Parallel activities and interactions between antimicrobial peptides and complement in host defense at the airway epithelial surface.
Molecular immunology Nov, 2015 | Pubmed ID: 26597202
The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma.
Oncotarget Jan, 2016 | Pubmed ID: 26658106
Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial.
PloS one , 2015 | Pubmed ID: 26659582
Regulation of YKL-40 expression by corticosteroids: effect on pro-inflammatory macrophages in vitro and its modulation in COPD in vivo.
Respiratory research Dec, 2015 | Pubmed ID: 26696093
TNF-α and IL-1β-activated human mesenchymal stromal cells increase airway epithelial wound healing in vitro via activation of the epidermal growth factor receptor.
Respiratory research Jan, 2016 | Pubmed ID: 26753875
MicroRNA-223 controls the expression of histone deacetylase 2: a novel axis in COPD.
Journal of molecular medicine (Berlin, Germany) Jun, 2016 | Pubmed ID: 26864305
IL-13 and the Airway Epithelium. It Is All in the Genes.
American journal of respiratory and critical care medicine Feb, 2016 | Pubmed ID: 26871666
Microbes and asthma: Opportunities for intervention.
The Journal of allergy and clinical immunology Mar, 2016 | Pubmed ID: 26947981
Murine models of cardiovascular comorbidity in chronic obstructive pulmonary disease.
American journal of physiology. Lung cellular and molecular physiology Jun, 2016 | Pubmed ID: 26993520
Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2016 | Pubmed ID: 27044108
Regeneration of the lung: Lung stem cells and the development of lung mimicking devices.
Respiratory research Apr, 2016 | Pubmed ID: 27107715
Antimicrobial Peptide P60.4Ac-Containing Creams and Gel for Eradication of Methicillin-Resistant Staphylococcus aureus from Cultured Skin and Airway Epithelial Surfaces.
Antimicrobial agents and chemotherapy Jul, 2016 | Pubmed ID: 27114278
Cellular response of mucociliary differentiated primary bronchial epithelial cells to diesel exhaust.
American journal of physiology. Lung cellular and molecular physiology Jul, 2016 | Pubmed ID: 27190060
Lung function decline in asthma patients with elevated bronchial CD8, CD4 and CD3 cells.
The European respiratory journal Aug, 2016 | Pubmed ID: 27230446
Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells.
Pulmonary pharmacology & therapeutics Aug, 2016 | Pubmed ID: 27246785
Childhood allergies and asthma: New insights on environmental exposures and local immunity at the lung barrier.
Current opinion in immunology Oct, 2016 | Pubmed ID: 27254380
The Dutch National Program for Respiratory Research.
The Lancet. Respiratory medicine May, 2016 | Pubmed ID: 27304557
Airway hyperresponsiveness in chronic obstructive pulmonary disease: A marker of asthma-chronic obstructive pulmonary disease overlap syndrome?
The Journal of allergy and clinical immunology Dec, 2016 | Pubmed ID: 27345171
ADAM17 and EGFR regulate IL-6 receptor and amphiregulin mRNA expression and release in cigarette smoke-exposed primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD).
Physiological reports Aug, 2016 | Pubmed ID: 27561911
Basic science of electronic cigarettes: assessment in cell culture and in vivo models.
Respiratory research 10, 2016 | Pubmed ID: 27717371
Functional characterisation of bone marrow-derived mesenchymal stromal cells from COPD patients.
ERJ open research Apr, 2016 | Pubmed ID: 27730190
Xenobiotic metabolism in differentiated human bronchial epithelial cells.
Archives of toxicology May, 2017 | Pubmed ID: 27738743
Cigarette Smoke Modulates Repair and Innate Immunity following Injury to Airway Epithelial Cells.
PloS one , 2016 | Pubmed ID: 27829065
Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.
The European respiratory journal Jan, 2017 | Pubmed ID: 28049170
Standard radiotherapy but not chemotherapy impairs systemic immunity in non-small cell lung cancer.
Oncoimmunology , 2016 | Pubmed ID: 28123900
Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae.
Respiratory research Jan, 2017 | Pubmed ID: 28129777
Antibacterial Defense of Human Airway Epithelial Cells from Chronic Obstructive Pulmonary Disease Patients Induced by Acute Exposure to Nontypeable Haemophilus influenzae: Modulation by Cigarette Smoke.
Journal of innate immunity , 2017 | Pubmed ID: 28171878
Proinflammatory Cytokines Impair Vitamin D-Induced Host Defense in Cultured Airway Epithelial Cells.
American journal of respiratory cell and molecular biology Jun, 2017 | Pubmed ID: 28231019
Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease.
The European respiratory journal Mar, 2017 | Pubmed ID: 28298400
Defining asthma-COPD overlap syndrome: a population-based study.
The European respiratory journal May, 2017 | Pubmed ID: 28461292
Use of airway epithelial cell culture to unravel the pathogenesis and study treatment in obstructive airway diseases.
Pulmonary pharmacology & therapeutics Aug, 2017 | Pubmed ID: 28502841
Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids.
The European respiratory journal Jun, 2017 | Pubmed ID: 28619964
The effect of tiotropium in combination with olodaterol on house dust mite-induced allergic airway disease.
Pulmonary pharmacology & therapeutics Aug, 2017 | Pubmed ID: 28687462
Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells.
Physiological reports Jul, 2017 | Pubmed ID: 28701525
Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation.
Frontiers in physiology , 2017 | Pubmed ID: 28751863
The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice.
International journal of molecular sciences Aug, 2017 | Pubmed ID: 28792474
Pre-surgical Pulmonary Rehabilitation in Asthma Patients Undergoing Bariatric Surgery.
Obesity surgery Nov, 2017 | Pubmed ID: 28831733
Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.
PloS one , 2017 | Pubmed ID: 28910300
Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure.
American journal of respiratory cell and molecular biology Feb, 2018 | Pubmed ID: 28933915
microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach.
Scientific reports Oct, 2017 | Pubmed ID: 28993685
Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions.
Toxicology in vitro : an international journal published in association with BIBRA Mar, 2018 | Pubmed ID: 29155131
Reprogramming of cellular metabolism: driver for airway remodelling in COPD?
The European respiratory journal Nov, 2017 | Pubmed ID: 29191957
Pulmonary function, exhaled nitric oxide and symptoms in asthma patients with obesity: a cross-sectional study.
Respiratory research Dec, 2017 | Pubmed ID: 29212496
Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population.
Nutrients Jan, 2018 | Pubmed ID: 29301349
Therapeutic Application of an Extract of Ameliorates the Development of Allergic Airway Disease.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2018 | Pubmed ID: 29352004
Effect of diesel exhaust generated by a city bus engine on stress responses and innate immunity in primary bronchial epithelial cell cultures.
Toxicology in vitro : an international journal published in association with BIBRA Apr, 2018 | Pubmed ID: 29408669
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.
The Journal of allergy and clinical immunology May, 2018 | Pubmed ID: 29425849
Assembly 3: Basic and Translational Sciences.
Breathe (Sheffield, England) Mar, 2018 | Pubmed ID: 29515672
Effects of E-Cigarette Use on Human Lung Tissue. On Harm Reduction and Causing Harm.
American journal of respiratory and critical care medicine Jul, 2018 | Pubmed ID: 29518342
Aberrant epithelial differentiation by cigarette smoke dysregulates respiratory host defence.
The European respiratory journal Apr, 2018 | Pubmed ID: 29545277
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?
Thorax Jun, 2018 | Pubmed ID: 29653970
Response to Comment on "Therapeutic Application of an Extract of Ameliorates the Development of Allergic Airway Disease".
Journal of immunology (Baltimore, Md. : 1950) May, 2018 | Pubmed ID: 29685947
Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease.
Chinese medical journal May, 2018 | Pubmed ID: 29692382
Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD.
Respirology (Carlton, Vic.) Nov, 2018 | Pubmed ID: 29696728
Basic and translational research in the .
The European respiratory journal May, 2018 | Pubmed ID: 29724787
A novel method for expansion and differentiation of mouse tracheal epithelial cells in culture.
Scientific reports May, 2018 | Pubmed ID: 29743551
Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.
Journal of innate immunity , 2018 | Pubmed ID: 29843140
Immunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsiveness.
Thorax Oct, 2018 | Pubmed ID: 29853649
Stem cell-based Lung-on-Chips: The best of both worlds?
Advanced drug delivery reviews Feb, 2019 | Pubmed ID: 30009883
Contribution of Host Defence Proteins and Peptides to Host-Microbiota Interactions in Chronic Inflammatory Lung Diseases.
Vaccines Jul, 2018 | Pubmed ID: 30060554
Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.
EBioMedicine Oct, 2018 | Pubmed ID: 30236449
Electronic cigarettes: a task force report from the European Respiratory Society.
The European respiratory journal Feb, 2019 | Pubmed ID: 30464018
How to write a response to the reviewers of your manuscript.
Breathe (Sheffield, England) Dec, 2018 | Pubmed ID: 30519299
Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls.
Biochimica et biophysica acta. Molecular and cell biology of lipids Mar, 2019 | Pubmed ID: 30528790
Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.
The European respiratory journal Apr, 2019 | Pubmed ID: 30846474
TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.
American journal of physiology. Lung cellular and molecular physiology Jul, 2019 | Pubmed ID: 30969812
TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms.
Journal of innate immunity , 2020 | Pubmed ID: 30970352
Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects.
Advances in experimental medicine and biology , 2019 | Pubmed ID: 30980358
Macrophage function in chronic obstructive pulmonary disease: The many faces of notch signalling.
EBioMedicine May, 2019 | Pubmed ID: 31047859
From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science.".
ERJ open research Apr, 2019 | Pubmed ID: 31111040
Extract of Helicobacter pylori Ameliorates Parameters of Airway Inflammation and Goblet Cell Hyperplasia following Repeated Allergen Exposure.
International archives of allergy and immunology , 2019 | Pubmed ID: 31242493
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.
Allergy Feb, 2020 | Pubmed ID: 31506971
Airway and alveolar epithelial cells in culture.
The European respiratory journal Nov, 2019 | Pubmed ID: 31515398
Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients.
PloS one , 2019 | Pubmed ID: 31527888
Perioperative proADM-change is associated with the development of acute respiratory distress syndrome in critically ill cardiac surgery patients: a prospective cohort study.
Biomarkers in medicine Sep, 2019 | Pubmed ID: 31544475
Translation of findings to patients with asthma: a timely and compelling challenge.
The European respiratory journal Oct, 2019 | Pubmed ID: 31601723
The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease.
PloS one , 2019 | Pubmed ID: 31647831
Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells.
Scientific reports Oct, 2019 | Pubmed ID: 31664154
Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease.
American journal of physiology. Lung cellular and molecular physiology Jan, 2020 | Pubmed ID: 31693390
Innate Immunity of the Lung.
Journal of innate immunity , 2020 | Pubmed ID: 31801141
Author Correction: Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells.
Scientific reports Jan, 2020 | Pubmed ID: 31937899
Tumor mutational load, CD8 T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients.
Cancer immunology, immunotherapy : CII May, 2020 | Pubmed ID: 32047958
ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly.
ERJ open research Jan, 2020 | Pubmed ID: 32154289
In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells.
Scientific reports Mar, 2020 | Pubmed ID: 32218519
Modulation of Airway Epithelial Innate Immunity and Wound Repair by M(GM-CSF) and M(M-CSF) Macrophages.
Journal of innate immunity , 2020 | Pubmed ID: 32289801
Short-term and long-term effect of a high-intensity pulmonary rehabilitation programme in obese patients with asthma: a randomised controlled trial.
The European respiratory journal Jul, 2020 | Pubmed ID: 32299852
Adiposity is a confounding factor which largely explains the association of serum vitamin D concentrations with C-reactive protein, leptin and adiponectin.
Cytokine Jul, 2020 | Pubmed ID: 32325367
Vitamin D Deficiency in Asthma and Chronic Obstructive Pulmonary Disease. A Chicken-or-Egg Story.
American journal of respiratory and critical care medicine Aug, 2020 | Pubmed ID: 32352312
Host-microbe cross-talk in the lung microenvironment: implications for understanding and treating chronic lung disease.
The European respiratory journal Aug, 2020 | Pubmed ID: 32430415
Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle.
Antimicrobial agents and chemotherapy Jul, 2020 | Pubmed ID: 32513797
Wnt/β-catenin signaling is critical for regenerative potential of distal lung epithelial progenitor cells in homeostasis and emphysema.
Stem cells (Dayton, Ohio) Nov, 2020 | Pubmed ID: 32526076
Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production via Multiple Mechanisms in Differentiated Airway Epithelial Cells.
Frontiers in cellular and infection microbiology , 2020 | Pubmed ID: 32637364
Impact of the Local Inflammatory Environment on Mucosal Vitamin D Metabolism and Signaling in Chronic Inflammatory Lung Diseases.
Frontiers in immunology , 2020 | Pubmed ID: 32754156
RAGE and TLR4 differentially regulate airway hyperresponsiveness: Implications for COPD.
Allergy Apr, 2021 | Pubmed ID: 32799375
An emerging class of air pollutants: Potential effects of microplastics to respiratory human health?
The Science of the total environment Dec, 2020 | Pubmed ID: 32827829
A new portable sampler to monitor pollen at street level in the environment of patients.
The Science of the total environment Nov, 2020 | Pubmed ID: 32887011
Air-Liquid Interface Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations.
Applied in vitro toxicology Jun, 2018 | Pubmed ID: 32953944
Bronchial gene expression signature associated with rate of subsequent FEV decline in individuals with and at risk of COPD.
Thorax Jan, 2022 | Pubmed ID: 33972452
Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant.
The European respiratory journal Jan, 2022 | Pubmed ID: 34049951
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes.
Scientific reports Jun, 2021 | Pubmed ID: 34145303
Repairing damaged lungs using regenerative therapy.
Current opinion in pharmacology Aug, 2021 | Pubmed ID: 34161852
Comparison of genome-wide gene expression profiling by RNA Sequencing microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?
ERJ open research Apr, 2021 | Pubmed ID: 34164552
The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients.
International journal of molecular sciences Jul, 2021 | Pubmed ID: 34360796
Disease modeling following organoid-based expansion of airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology Oct, 2021 | Pubmed ID: 34378410
Factors associated with physical activity among COPD patients with mild or moderate airflow obstruction.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace Sep, 2021 | Pubmed ID: 34523325
Kallikrein-related peptidase 5 contributes to the remodeling and repair of bronchial epithelium.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2021 | Pubmed ID: 34582061
Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.
Allergy Feb, 2022 | Pubmed ID: 34698405
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8 T cell responses following COVID-19.
Nature immunology Jan, 2022 | Pubmed ID: 34937933
The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease.
PloS one , 2022 | Pubmed ID: 34990493
Lung epithelial cells interact with immune cells and bacteria to shape the microenvironment in tuberculosis.
Thorax Apr, 2022 | Pubmed ID: 35017314
Organoid-based expansion of patient-derived primary alveolar type 2 cells for establishment of alveolus epithelial Lung-Chip cultures.
American journal of physiology. Lung cellular and molecular physiology Apr, 2022 | Pubmed ID: 35137633
Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD.
European respiratory review : an official journal of the European Respiratory Society Mar, 2022 | Pubmed ID: 35321933
Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort.
Pathogens (Basel, Switzerland) Mar, 2022 | Pubmed ID: 35335664
Dysregulated mitochondrial metabolism upon cigarette smoke exposure in various human bronchial epithelial cell models.
Disease models & mechanisms Mar, 2022 | Pubmed ID: 35344036
High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD.
Scientific reports Apr, 2022 | Pubmed ID: 35379844
Vitamin D supplementation in chronic obstructive pulmonary disease patients with low serum vitamin D: a randomized controlled trial.
The American journal of clinical nutrition Aug, 2022 | Pubmed ID: 35383823
Personalized Pollen Monitoring and Symptom Scores: A Feasibility Study in Grass Pollen Allergic Patients.
Frontiers in allergy , 2021 | Pubmed ID: 35387060
3D Lung-on-Chip Model Based on Biomimetically Microcurved Culture Membranes.
ACS biomaterials science & engineering Jun, 2022 | Pubmed ID: 35502997
Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein.
The EMBO journal Jun, 2022 | Pubmed ID: 35506364
Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response.
Clinical and translational allergy Aug, 2022 | Pubmed ID: 36036237
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes.
Cellular and molecular life sciences : CMLS Sep, 2022 | Pubmed ID: 36045259
Early transcriptional responses of bronchial epithelial cells to whole cigarette smoke mirror those of in-vivo exposed human bronchial mucosa.
Respiratory research Sep, 2022 | Pubmed ID: 36056356
The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis.
Microbiome Oct, 2022 | Pubmed ID: 36258251
Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling.
Antioxidants (Basel, Switzerland) Oct, 2022 | Pubmed ID: 36290742
SARS-CoV-2-specific CD4 and CD8 T cell responses can originate from cross-reactive CMV-specific T cells.
eLife Nov, 2022 | Pubmed ID: 36408799
Combination of IL-17A/F and TNF-α uniquely alters the bronchial epithelial cell proteome to enhance proteins that augment neutrophil migration.
Journal of inflammation (London, England) Dec, 2022 | Pubmed ID: 36517803
Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD.
Thorax Apr, 2023 | Pubmed ID: 36598042
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
Nature genetics Mar, 2023 | Pubmed ID: 36914875
Smoking increases expression of the SARS-CoV-2 spike protein-binding long ACE2 isoform in bronchial epithelium.
Respiratory research May, 2023 | Pubmed ID: 37170105
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