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Department of Hematology
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Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes.
Haematologica Oct, 2015 | Pubmed ID: 26185170
Gli1 Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target.
Cell stem cell Jun, 2017 | Pubmed ID: 28457748
Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.
Blood Oct, 2020 | Pubmed ID: 32726410
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
Journal of the American Society of Nephrology : JASN Dec, 2020 | Pubmed ID: 32938648
Decoding myofibroblast origins in human kidney fibrosis.
Nature Jan, 2021 | Pubmed ID: 33176333
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Cell stem cell Apr, 2021 | Pubmed ID: 33301706
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.
Molecular systems biology Jan, 2021 | Pubmed ID: 33502086
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML.
Blood Jul, 2021 | Pubmed ID: 33831168
Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion.
Blood advances Mar, 2022 | Pubmed ID: 35016204
Single-cell analysis of cultured bone marrow stromal cells reveals high similarity to fibroblasts in situ.
Experimental hematology Jun, 2022 | Pubmed ID: 35341805
Mapping the cardiac vascular niche in heart failure.
Nature communications May, 2022 | Pubmed ID: 35641541
Spatial multi-omic map of human myocardial infarction.
Nature Aug, 2022 | Pubmed ID: 35948637
Adult human kidney organoids originate from CD24 cells and represent an advanced model for adult polycystic kidney disease.
Nature genetics Nov, 2022 | Pubmed ID: 36303074
Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition.
Blood advances May, 2023 | Pubmed ID: 36649572
A combinatorial panel for flow cytometry-based isolation of enteric nervous system cells from human intestine.
EMBO reports Apr, 2023 | Pubmed ID: 36852936
Erasmus Medical Center
Naomi J. M. Kakiailatu1,
Laura E. Kuil1,2,
Eric Bindels3,
Joke T. M. Zink3,
Michael Vermeulen3,
Veerle Melotte4,
Maria M. Alves1
1Department of Clinical Genetics, Erasmus University Medical Center - Sophia Children's Hospital,
2Division of Psychosocial Research and Epidemiology, the Netherlands Cancer Institute,
3Department of Hematology, Erasmus Medical Center,
4Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center
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