Leeds Institute of Cardiovascular and Metabolic Medicine
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Analysis of oxygen-sensitive human cardiac L-type Ca2+ channel alpha1C subunit (hHT Isoform).
Methods in enzymology , 2004 | Pubmed ID: 15063682
Testosterone is a potent inhibitor of L-type Ca(2+) channels.
Biochemical and biophysical research communications May, 2004 | Pubmed ID: 15120629
Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2005 | Pubmed ID: 15494446
Constitutive activity of endogenous receptors by inducible Gq overexpression.
Biochemical and biophysical research communications Jun, 2005 | Pubmed ID: 15883008
Constitutive activity of human angiotensin II type-1 receptors by Gq overexpression.
Biochemical and biophysical research communications Aug, 2005 | Pubmed ID: 15992776
A central role for ROS in the functional remodelling of L-type Ca2+ channels by hypoxia.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Dec, 2005 | Pubmed ID: 16321794
Molecular requirements for L-type Ca2+ channel blockade by testosterone.
Cell calcium Jul, 2007 | Pubmed ID: 17173968
H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death.
Pflugers Archiv : European journal of physiology Mar, 2008 | Pubmed ID: 18043941
Modulation of hTREK-1 by carbon monoxide.
Neuroreport Feb, 2008 | Pubmed ID: 18303579
Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species.
The Journal of biological chemistry Sep, 2008 | Pubmed ID: 18596041
Ion channels as effectors in carbon monoxide signaling.
Communicative & integrative biology May, 2009 | Pubmed ID: 19641743
Hypoxia and neurodegeneration.
Annals of the New York Academy of Sciences Oct, 2009 | Pubmed ID: 19845619
Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2011 | Pubmed ID: 21248240
Modulation of ion channels by hydrogen sulfide.
Antioxidants & redox signaling Jul, 2012 | Pubmed ID: 22074224
Cellular consequences of the expression of Alzheimer's disease-causing presenilin 1 mutations in human neuroblastoma (SH-SY5Y) cells.
Brain research Mar, 2012 | Pubmed ID: 22297172
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition.
The Journal of biological chemistry Jul, 2012 | Pubmed ID: 22593583
Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current.
American journal of respiratory and critical care medicine Oct, 2012 | Pubmed ID: 22822026
Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2013 | Pubmed ID: 23671274
Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide.
The Journal of biological chemistry Jun, 2014 | Pubmed ID: 24719320
Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels.
Pflugers Archiv : European journal of physiology Feb, 2015 | Pubmed ID: 24744106
Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2014 | Pubmed ID: 25183670
Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.
Journal of cell science Jan, 2015 | Pubmed ID: 25413349
H2S does not regulate proliferation via T-type Ca2+ channels.
Biochemical and biophysical research communications Jun, 2015 | Pubmed ID: 25918023
Heme Oxygenase-1 Influences Apoptosis via CO-mediated Inhibition of K+ Channels.
Advances in experimental medicine and biology , 2015 | Pubmed ID: 26303499
Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide.
Advances in experimental medicine and biology , 2015 | Pubmed ID: 26303500
Regulation of the T-type Ca(2+) channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2 S in nociception.
The Journal of physiology Aug, 2016 | Pubmed ID: 26804000
Redox-Dependent Modulation of T-Type Ca(2+) Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P.
Antioxidants & redox signaling Aug, 2016 | Pubmed ID: 27306612
Heme oxygenase-1 derived carbon monoxide suppresses Aβ toxicity in astrocytes.
Cell death & disease Jun, 2017 | Pubmed ID: 28617444
A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K channels in carbon monoxide-induced proarrhythmic early afterdepolarizations.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2017 | Pubmed ID: 28743763
Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K channel Kv1.5.
Cell death & disease Nov, 2017 | Pubmed ID: 29095440
Piezo1 channel activation mimics high glucose as a stimulator of insulin release.
Scientific reports Nov, 2019 | Pubmed ID: 31727906
Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy.
Journal of the American Heart Association Sep, 2020 | Pubmed ID: 32892688
Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis.
Nature communications Mar, 2021 | Pubmed ID: 33772024
Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism.
Cell death & disease Apr, 2021 | Pubmed ID: 33828089
Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1.
Scientific reports Apr, 2021 | Pubmed ID: 33854181
Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling.
Communications biology Jun, 2023 | Pubmed ID: 37336943
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