Cindi M. Morshead

Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations.

The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells.

Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis.

Disguising adult neural stem cells.

Adult neural stem cells: attempting to solve the identity crisis.

Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release.

Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury.

Exploiting the properties of adult stem cells for the treatment of disease.

Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells.

True monolayer cell culture in a confined 3D microenvironment enables lineage informatics.

Extramedullary chitosan channels promote survival of transplanted neural stem and progenitor cells and create a tissue bridge after complete spinal cord transection.

Delayed implantation of intramedullary chitosan channels containing nerve grafts promotes extensive axonal regeneration after spinal cord injury.

Don't look: growing clonal versus nonclonal neural stem cell colonies.

Neurogenic potential of isolated precursor cells from early post-gastrula somitic tissue.

Cyclosporin A has direct effects on adult neural precursor cells.

Potential and pitfalls of stem cell therapy in old age.

Endogenous radial glial cells support regenerating axons after spinal cord transection.

Immunosuppression promotes endogenous neural stem and progenitor cell migration and tissue regeneration after ischemic injury.

Transport of epidermal growth factor in the stroke-injured brain.

Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injury.

Adult stem cells and bioengineering strategies for the treatment of cerebral ischemic stroke.

Controlled epi-cortical delivery of epidermal growth factor for the stimulation of endogenous neural stem cell proliferation in stroke-injured brain.

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels.

Adult subependymal neural precursors, but not differentiated cells, undergo rapid cathodal migration in the presence of direct current electric fields.

Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury.

The Effect of Growth Factors and Soluble Nogo66 Receptor Protein on Transplanted Neural Stem/Progenitor Survival and Axonal Regeneration after Complete Transection of Rat Spinal Cord.

Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma.

Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics.

Role of neural precursor cells in promoting repair following stroke.

Notch signaling imparts and preserves neural stem characteristics in the adult brain.

A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.

Effectiveness of micron-sized superparamagnetic iron oxide particles as markers for detection of migration of bone marrow-derived mesenchymal stromal cells in a stroke model.

Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke.

Neural stem and progenitor cells in the aged subependyma are activated by the young niche.

Prosurvival factors derived from the embryonic brain promote adult neural stem cell survival.

Primitive neural stem cells in the adult mammalian brain give rise to GFAP-expressing neural stem cells.

Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway.

Biphasic monopolar electrical stimulation induces rapid and directed galvanotaxis in adult subependymal neural precursors.

A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation.

Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.

Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury.

Assessing cognitive function following medial prefrontal stroke in the rat.

Adult Neural Stem Cells from the Subventricular Zone Give Rise to Reactive Astrocytes in the Cortex after Stroke.

Cyclosporin A enhances neurogenesis in the dentate gyrus of the hippocampus.

Enriched rehabilitation promotes motor recovery in rats exposed to neonatal hypoxia-ischemia.

Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord.

Response to: Where do you come from and what are you going to become, reactive astrocyte?

Stem cells in the adult CNS revealed: examining their regulation by myelin basic protein.

Building a central nervous system: The neural stem cell lineage revealed.

Environmental Factors That Influence Stem Cell Migration: An "Electric Field".

In Vitro Maturation of Human iPSC-Derived Neuroepithelial Cells Influences Transplant Survival in the Stroke-Injured Rat Brain.

Quiescent Oct4 Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein NSCs in the Adult Mouse Brain.

Home sweet home: the neural stem cell niche throughout development and after injury.

Abstracts and Workshops 7th National Spinal Cord Injury Conference November 9 - 11, 2017 Fallsview Casino Resort Niagara Falls, Ontario, Canada.

Calcium influx differentially regulates migration velocity and directedness in response to electric field application.

Cyclosporin A-Mediated Activation of Endogenous Neural Precursor Cells Promotes Cognitive Recovery in a Mouse Model of Stroke.

Neural stem cell heterogeneity in the mammalian forebrain.

Skin-derived precursor cells undergo substrate-dependent galvanotaxis that can be modified by neighbouring cells.

Initial cell maturity changes following transplantation in a hyaluronan-based hydrogel and impacts therapeutic success in the stroke-injured rodent brain.

Dual embryonic origin of the mammalian enteric nervous system.

Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats.

Transplantation of Directly Reprogrammed Human Neural Precursor Cells Following Stroke Promotes Synaptogenesis and Functional Recovery.

Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells.

The optoelectronic microrobot: A versatile toolbox for micromanipulation.

A 3D Printed Device for Low Cost Neural Stimulation in Mice.

Age- and sex-dependent effects of metformin on neural precursor cells and cognitive recovery in a model of neonatal stroke.

Cranial irradiation in juvenile mice leads to early and sustained defects in the stem and progenitor cell pools and late cognitive impairments.

Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains.

Lineage tracing reveals the hierarchical relationship between neural stem cell populations in the mouse forebrain.

Injectable hydrogel enables local and sustained co-delivery to the brain: Two clinically approved biomolecules, cyclosporine and erythropoietin, accelerate functional recovery in rat model of stroke.

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury.

Electric Field Application Regulates Neural Precursor Cell Behavior in the Adult Mammalian Forebrain.

Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin.

Stem cell heterogeneity and regenerative competence: the enormous potential of rare cells.

Constraint-induced movement therapy promotes motor recovery after neonatal stroke in the absence of neural precursor activation.

Niche-dependent inhibition of neural stem cell proliferation and oligodendrogenesis is mediated by the presence of myelin basic protein.

Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation.

Transplantation of Human Cortically-Specified Neuroepithelial Progenitor Cells Leads to Improved Functional Outcomes in a Mouse Model of Stroke.

Metformin effects on brain development following cranial irradiation in a mouse model.

Novel Electrode Designs for Neurostimulation in Regenerative Medicine: Activation of Stem Cells.

Substrate-Dependent Galvanotaxis of Directly Reprogrammed Human Neural Precursor Cells.

Subacute metformin treatment reduces inflammation and improves functional outcome following neonatal hypoxia ischemia.

Editorial: Regulation of Cellular Reprogramming for Post-stroke Tissue Regeneration: Bridging a Gap Between Basic Research and Clinical Application.

Regulating Endogenous Neural Stem Cell Activation to Promote Spinal Cord Injury Repair.

Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke.

Facile Fabrication of Injectable Alginate and Poly(3,4-ethylenedioxythiophene)-Based Soft Electrodes toward the Goal of Neuro-Regenerative Applications.

Tunable Surface Charge Enables the Electrostatic Adsorption-Controlled Release of Neuroprotective Peptides from a Hydrogel-Nanoparticle Drug Delivery System.

Bio-inspired conductive adhesive based on calcium-free alginate hydrogels for bioelectronic interfaces.

A novel ex vivo assay to define charge-balanced electrical stimulation parameters for neural precursor cell activation in vivo.

Metformin Improves Functional Outcomes, Activates Neural Precursor Cells, and Modulates Microglia in a Sex-Dependent Manner After Spinal Cord Injury.

Fate Specification of GFAP-Negative Primitive Neural Stem Cells and Their Progeny at Clonal Resolution.

Cryogel-based neurostimulation electrodes to activate endogenous neural precursor cells.

Metformin treatment reduces inflammation, dysmyelination and disease severity in a mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis.

Inhibition of Apoptosis in a Model of Ischemic Stroke Leads to Enhanced Cell Survival, Endogenous Neural Precursor Cell Activation and Improved Functional Outcomes.

Ectopic Expression of Neurod1 Is Sufficient for Functional Recovery following a Sensory-Motor Cortical Stroke.

Primitive and Definitive Neural Precursor Cells Are Present in Human Cerebral Organoids.

Glia-to-neuron reprogramming to the rescue?

Electrical Stimulation for Stem Cell-Based Neural Repair: Zapping the Field to Action.

Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain.

Biodegradable stimulating electrodes for resident neural stem cell activation in vivo.

Microglia in the spinal cord stem cell niche regulate neural precursor cell proliferation via soluble CD40 in response to myelin basic protein.