Department of Biomedical Engineering,
Department of Macromolecular Science and Engineering
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Microfluidics for flow cytometric analysis of cells and particles.
Physiological measurement Jun, 2005 | Pubmed ID: 15798290
Lateral propagation of EGF signaling after local stimulation is dependent on receptor density.
Developmental cell Aug, 2002 | Pubmed ID: 12194855
Micro- and nanotechnologies for studying cellular function.
Current topics in medicinal chemistry , 2003 | Pubmed ID: 12570859
Selective chemical treatment of cellular microdomains using multiple laminar streams.
Chemistry & biology Feb, 2003 | Pubmed ID: 12618184
Passively driven integrated microfluidic system for separation of motile sperm.
Analytical chemistry Apr, 2003 | Pubmed ID: 12705601
Isolation of motile spermatozoa from semen samples using microfluidics.
Reproductive biomedicine online Jul-Aug, 2003 | Pubmed ID: 12930579
Rethinking gamete/embryo isolation and culture with microfluidics.
Human reproduction update Sep-Oct, 2003 | Pubmed ID: 14640377
Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change.
Journal of the American Chemical Society Dec, 2003 | Pubmed ID: 14640622
Fabrication of microfluidic mixers and artificial vasculatures using a high-brightness diode-pumped Nd:YAG laser direct write method.
Lab on a chip Nov, 2003 | Pubmed ID: 15007466
Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation.
The Analyst Nov, 2004 | Pubmed ID: 15508030
Computerized microfluidic cell culture using elastomeric channels and Braille displays.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2004 | Pubmed ID: 15514025
Fabrication of reconfigurable protein matrices by cracking.
Nature materials May, 2005 | Pubmed ID: 15834415
Computer-controlled microcirculatory support system for endothelial cell culture and shearing.
Analytical chemistry Jul, 2005 | Pubmed ID: 15987102
IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm.
Human reproduction (Oxford, England) Feb, 2006 | Pubmed ID: 16199424
Microfluidic applications for andrology.
Journal of andrology Nov-Dec, 2005 | Pubmed ID: 16291957
Handheld recirculation system and customized media for microfluidic cell culture.
Lab on a chip Jan, 2006 | Pubmed ID: 16372083
Microscale integrated sperm sorter.
Methods in molecular biology (Clifton, N.J.) , 2006 | Pubmed ID: 16508075
The effect of continuous wavy micropatterns on silicone substrates on the alignment of skeletal muscle myoblasts and myotubes.
Biomaterials Aug, 2006 | Pubmed ID: 16650470
A surface-modified sperm sorting device with long-term stability.
Biomedical microdevices Jun, 2006 | Pubmed ID: 16688569
Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture.
Journal of biomedical optics Sep-Oct, 2006 | Pubmed ID: 17092147
Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture.
Biomedical microdevices Apr, 2007 | Pubmed ID: 17160707
Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices.
Analytical chemistry Feb, 2007 | Pubmed ID: 17263345
Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification.
Analytical chemistry Feb, 2007 | Pubmed ID: 17297936
Leakage-free bonding of porous membranes into layered microfluidic array systems.
Analytical chemistry May, 2007 | Pubmed ID: 17388566
Tuneable elastomeric nanochannels for nanofluidic manipulation.
Nature materials Jun, 2007 | Pubmed ID: 17486084
Efficient formation of uniform-sized embryoid bodies using a compartmentalized microchannel device.
Lab on a chip Jun, 2007 | Pubmed ID: 17538720
Assessment of sperm chemokinesis with exposure to jelly coats of sea urchin eggs and resact: a microfluidic experiment and numerical study.
The Journal of experimental biology Nov, 2007 | Pubmed ID: 17951422
Small volume low mechanical stress cytometry using computer-controlled Braille display microfluidics.
Lab on a chip Nov, 2007 | Pubmed ID: 17960277
Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2007 | Pubmed ID: 18006663
Reversible on-demand cell alignment using reconfigurable microtopography.
Biomaterials Apr, 2008 | Pubmed ID: 18192004
DNA linearization through confinement in nanofluidic channels.
Analytical and bioanalytical chemistry Aug, 2008 | Pubmed ID: 18340435
Individually programmable cell stretching microwell arrays actuated by a Braille display.
Biomaterials Jun, 2008 | Pubmed ID: 18342367
Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves.
Analytical chemistry Aug, 2008 | Pubmed ID: 18576665
Liquid and surfactant delivery into pulmonary airways.
Respiratory physiology & neurobiology Nov, 2008 | Pubmed ID: 18585985
Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs.
Biomaterials Feb, 2009 | Pubmed ID: 19064284
A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development.
Zebrafish Jun, 2009 | Pubmed ID: 19292670
Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids.
Biomaterials Jun, 2009 | Pubmed ID: 19304321
Hard top soft bottom microfluidic devices for cell culture and chemical analysis.
Analytical chemistry May, 2009 | Pubmed ID: 19382754
Quantitative inference of cellular parameters from microfluidic cell culture systems.
Biotechnology and bioengineering Aug, 2009 | Pubmed ID: 19388086
External compression-induced fracture patterning on the surface of poly(dimethylsiloxane) cubes and microspheres.
Langmuir : the ACS journal of surfaces and colloids Mar, 2009 | Pubmed ID: 19437776
Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells.
PloS one , 2009 | Pubmed ID: 19484126
Microfluidic culture of single human embryonic stem cell colonies.
Lab on a chip Jun, 2009 | Pubmed ID: 19495459
Unsteady propagation of a liquid plug in a liquid-lined straight tube.
Physics of fluids (Woodbury, N.Y. : 1994) Jun, 2008 | Pubmed ID: 19547724
The mechanical properties of a surface-modified layer on poly(dimethylsiloxane).
Journal of materials research Jan, 2008 | Pubmed ID: 19779588
Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device.
Biomedical microdevices Feb, 2010 | Pubmed ID: 19830565
Microfluidics cell culture with sensing and SqueezeFluidics.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference , 2009 | Pubmed ID: 19964166
Bioengineered three-dimensional physiological model of colonic longitudinal smooth muscle in vitro.
Tissue engineering. Part C, Methods Oct, 2010 | Pubmed ID: 20001822
Dynamics of liquid plugs of buffer and surfactant solutions in a micro-engineered pulmonary airway model.
Langmuir : the ACS journal of surfaces and colloids Mar, 2010 | Pubmed ID: 20017471
Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids.
Integrative biology : quantitative biosciences from nano to macro Dec, 2009 | Pubmed ID: 20027373
High-speed tuning of visible laser wavelength using a nanoimprinted grating optical tunable filter.
Applied physics letters Nov, 2009 | Pubmed ID: 20052314
Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers.
Analytical chemistry Mar, 2010 | Pubmed ID: 20178370
Patterned electrode-based amperometric gas sensor for direct nitric oxide detection within microfluidic devices.
Analytical chemistry Apr, 2010 | Pubmed ID: 20329749
Single cell trapping in larger microwells capable of supporting cell spreading and proliferation.
Microfluidics and nanofluidics Feb, 2010 | Pubmed ID: 20352022
Polymeric aqueous biphasic systems for non-contact cell printing on cells: engineering heterocellular embryonic stem cell niches.
Advanced materials (Deerfield Beach, Fla.) Jun, 2010 | Pubmed ID: 20449846
Guided corona generates wettability patterns that selectively direct cell attachment inside closed microchannels.
Biomedical microdevices Oct, 2010 | Pubmed ID: 20495872
Simultaneous fabrication of PDMS through-holes for three-dimensional microfluidic applications.
Lab on a chip Aug, 2010 | Pubmed ID: 20502832
Instantaneous fabrication of arrays of normally closed, adjustable, and reversible nanochannels by tunnel cracking.
Lab on a chip Jun, 2010 | Pubmed ID: 20517560
Integrated Elastomeric Components for Autonomous Regulation of Sequential and Oscillatory Flow Switching in Microfluidic Devices.
Nature physics Jun, 2010 | Pubmed ID: 20526435
Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems.
Integrative biology : quantitative biosciences from nano to macro Jun, 2010 | Pubmed ID: 20535416
The art of reporter proteins in science: past, present and future applications.
BMB reports Jul, 2010 | Pubmed ID: 20663405
Transwells with Microstamped Membranes Produce Micropatterned Two-Dimensional and Three-Dimensional Co-Cultures.
Tissue engineering. Part C, Methods Aug, 2010 | Pubmed ID: 20673133
Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves.
Lab on a chip Nov, 2010 | Pubmed ID: 20835429
Micropatterning bacterial suspensions using aqueous two phase systems.
The Analyst Nov, 2010 | Pubmed ID: 20838666
Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells.
Integrative biology : quantitative biosciences from nano to macro Nov, 2010 | Pubmed ID: 20871938
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array.
The Analyst Feb, 2011 | Pubmed ID: 20967331
Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow.
Analytical chemistry Nov, 2010 | Pubmed ID: 20979407
High-density fabrication of normally closed microfluidic valves by patterned deactivation of oxidized polydimethylsiloxane.
Lab on a chip Feb, 2011 | Pubmed ID: 21132212
Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model.
Lab on a chip Feb, 2011 | Pubmed ID: 21152526
Phase-locked signals elucidate circuit architecture of an oscillatory pathway.
PLoS computational biology , 2010 | Pubmed ID: 21203481
Flexible fabrication and applications of polymer nanochannels and nanoslits.
Chemical Society reviews Jul, 2011 | Pubmed ID: 21442106
Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations.
Current topics in medicinal chemistry , 2011 | Pubmed ID: 21446910
Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model.
Biomedical microdevices Aug, 2011 | Pubmed ID: 21487664
Aqueous biphasic microprinting approach to tissue engineering.
Biomicrofluidics , 2011 | Pubmed ID: 21522494
Microprinted feeder cells guide embryonic stem cell fate.
Biotechnology and bioengineering May, 2011 | Pubmed ID: 21538333
Hi-Fi transmission of periodic signals amid cell-to-cell variability.
Molecular bioSystems Jul, 2011 | Pubmed ID: 21559542
Precisely targeted delivery of cells and biomolecules within microchannels using aqueous two-phase systems.
Biomedical microdevices Dec, 2011 | Pubmed ID: 21769637
Responses of endothelial cells to extremely slow flows.
Biomicrofluidics Jun, 2011 | Pubmed ID: 21799717
Next-generation integrated microfluidic circuits.
Lab on a chip Sep, 2011 | Pubmed ID: 21799977
Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics.
Lab on a chip Oct, 2011 | Pubmed ID: 21892481
Receptor differential activation and cooperativity better explain cellular preference for different chemoattractant gradient shapes in an EGFR system.
Integrative biology : quantitative biosciences from nano to macro Oct, 2011 | Pubmed ID: 21918787
Rethinking in vitro embryo culture: new developments in culture platforms and potential to improve assisted reproductive technologies.
Biology of reproduction Mar, 2012 | Pubmed ID: 21998170
Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates.
Biomedical microdevices Apr, 2012 | Pubmed ID: 22057945
Organs-on-a-Chip: A Focus on Compartmentalized Microdevices.
Annals of biomedical engineering Nov, 2011 | Pubmed ID: 22065201
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions.
The Biochemical journal Mar, 2012 | Pubmed ID: 22142194
384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids.
Biotechnology and bioengineering May, 2012 | Pubmed ID: 22161651
Constant flow-driven microfluidic oscillator for different duty cycles.
Analytical chemistry Jan, 2012 | Pubmed ID: 22206453
Rapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning.
Tissue engineering. Part C, Methods Sep, 2012 | Pubmed ID: 22356298
Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation.
Lab on a chip Jun, 2012 | Pubmed ID: 22402469
Quantitative analysis of molecular absorption into PDMS microfluidic channels.
Annals of biomedical engineering Sep, 2012 | Pubmed ID: 22484830
Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.
Journal of controlled release : official journal of the Controlled Release Society Dec, 2012 | Pubmed ID: 22613880
Lab-on-a-chip biophotonics: its application to assisted reproductive technologies.
Journal of biophotonics Jun, 2012 | Pubmed ID: 22700221
Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers.
Small (Weinheim an der Bergstrasse, Germany) Oct, 2012 | Pubmed ID: 22761019
Aqueous two-phase system-derived biofilms for bacterial interaction studies.
Biomacromolecules Sep, 2012 | Pubmed ID: 22793044
Microfluidic systems: a new toolbox for pluripotent stem cells.
Biotechnology journal Feb, 2013 | Pubmed ID: 23125055
Nanoscale squeezing in elastomeric nanochannels for single chromatin linearization.
Nano letters Dec, 2012 | Pubmed ID: 23186544
Super-Resolution Imaging of PDMS Nanochannels by Single-Molecule Micelle-Assisted Blink Microscopy.
The journal of physical chemistry. B Jan, 2013 | Pubmed ID: 23256598
Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits.
Applied physics letters Dec, 2012 | Pubmed ID: 23284181
Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation.
Journal of the American Chemical Society Feb, 2013 | Pubmed ID: 23316688
Localized micro-scale disruption of cells using laser-generated focused ultrasound.
Journal of biophotonics Feb, 2013 | Pubmed ID: 23420806
Large-Scale, Ultrapliable, and Free-Standing Nanomembranes.
Advanced materials (Deerfield Beach, Fla.) Feb, 2013 | Pubmed ID: 23423854
Microfluidic oscillators with widely tunable periods.
Lab on a chip Mar, 2013 | Pubmed ID: 23429765
Polymeric Aqueous Biphasic System Rehydration Facilitates High Throughput Cell Exclusion Patterning For Cell Migration Studies.
Advanced functional materials Aug, 2011 | Pubmed ID: 23519702
Room Temperature Phosphorescence of Metal-free Organic Materials in Amorphous Polymer Matrices.
Journal of the American Chemical Society Mar, 2013 | Pubmed ID: 23521108
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