Health Sciences and Technology
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Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.
Science (New York, N.Y.) Sep, 2017 | Pubmed ID: 28912244
Spatial Control of Bacteria Using Screen Printing.
3D printing and additive manufacturing Dec, 2016 | Pubmed ID: 29577061
Advances in bacterial cancer therapies using synthetic biology.
Current opinion in systems biology Oct, 2017 | Pubmed ID: 29881788
Synthetic Biology and Engineered Live Biotherapeutics: Toward Increasing System Complexity.
Cell systems Jul, 2018 | Pubmed ID: 30048620
Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli.
iScience Apr, 2019 | Pubmed ID: 30954530
Rapid screening of engineered microbial therapies in a 3D multicellular model.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2019 | Pubmed ID: 30996123
Programmable bacteria induce durable tumor regression and systemic antitumor immunity.
Nature medicine Jul, 2019 | Pubmed ID: 31270504
Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies.
Science translational medicine Feb, 2020 | Pubmed ID: 32051224
Engineered Probiotics for Detection and Treatment of Inflammatory Intestinal Diseases.
Frontiers in bioengineering and biotechnology , 2020 | Pubmed ID: 32296696
Engineered Bacterial Production of Volatile Methyl Salicylate.
ACS synthetic biology Jan, 2021 | Pubmed ID: 33331760
Quantitative measurements of early alphaviral replication dynamics in single cells reveals the basis for superinfection exclusion.
Cell systems Mar, 2021 | Pubmed ID: 33515490
Engineering bacteria for cancer therapy.
Emerging topics in life sciences Nov, 2019 | Pubmed ID: 33523173
Enhancing the tropism of bacteria via genetically programmed biosensors.
Nature biomedical engineering Jan, 2022 | Pubmed ID: 34326488
The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Gastroenterology Mar, 2022 | Pubmed ID: 34883119
CAR-T cells SEAK help from enzymes.
Nature chemical biology Feb, 2022 | Pubmed ID: 34969971
Bacterial couriers as cancer vaccines.
Nature biomedical engineering Jan, 2022 | Pubmed ID: 35058588
Reimagining cancer research with art.
Nature reviews. Cancer Apr, 2022 | Pubmed ID: 35140359
A programmable encapsulation system improves delivery of therapeutic bacteria in mice.
Nature biotechnology Aug, 2022 | Pubmed ID: 35301496
A rapid screening platform to coculture bacteria within tumor spheroids.
Nature protocols Oct, 2022 | Pubmed ID: 35906291
Engineering bacteria as interactive cancer therapies.
Science (New York, N.Y.) Nov, 2022 | Pubmed ID: 36423303
Assessing chemotherapy dosing strategies in a spatial cell culture model.
Frontiers in oncology , 2022 | Pubmed ID: 36505801
Design of combination therapy for engineered bacterial therapeutics in non-small cell lung cancer.
Scientific reports Dec, 2022 | Pubmed ID: 36513723
Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity.
Science advances Mar, 2023 | Pubmed ID: 36888717
Engineered Bacteria for Short-Chain-Fatty-Acid-Repressed Expression of Biotherapeutic Molecules.
Microbiology spectrum Mar, 2023 | Pubmed ID: 36939337
Engineered bacterial swarm patterns as spatial records of environmental inputs.
Nature chemical biology Jul, 2023 | Pubmed ID: 37142806
Probiotic-guided CAR-T cells for solid tumor targeting.
Science (New York, N.Y.) Oct, 2023 | Pubmed ID: 37824640
Engineering Probiotic E. coli Nissle 1917 for Release of Therapeutic Nanobodies.
Methods in molecular biology (Clifton, N.J.) , 2024 | Pubmed ID: 38070121
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.
Nature communications Jan, 2024 | Pubmed ID: 38245513
1Health Sciences and Technology, Massachusetts Institute of Technology,
2Department of Bioengineering, University of California, San Diego ,
3Biocircuits Institute, University of California, San Diego ,
4Molecular Biology Section, Division of Biological Science, University of California, San Diego ,
5, Broad Institute of Harvard and MIT,
6Department of Medicine, Brigham and Women's Hospital,
7Electrical Engineering and Computer Science and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology,
8, Howard Hughes Medical Institute
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