Department of Infectious Diseases,
Parasitology Unit,
Department of Infectious Diseases, Parasitology Unit
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Genetically modified Plasmodium parasites as a protective experimental malaria vaccine.
Nature Jan, 2005 | Pubmed ID: 15580261
Unusual properties of Plasmodium falciparum actin: new insights into microfilament dynamics of apicomplexan parasites.
FEBS letters Jan, 2005 | Pubmed ID: 15670824
Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2005 | Pubmed ID: 15699336
A Plasmodium actin-depolymerizing factor that binds exclusively to actin monomers.
Molecular biology of the cell Sep, 2005 | Pubmed ID: 15975905
Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells.
The American journal of pathology Jul, 2007 | Pubmed ID: 17591958
Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells.
The Journal of infectious diseases Aug, 2007 | Pubmed ID: 17624847
Assessment of antibody protection against malaria sporozoites must be done by mosquito injection of sporozoites.
The American journal of pathology Oct, 2007 | Pubmed ID: 17823294
Vaccines against malaria - an update.
The FEBS journal Sep, 2007 | Pubmed ID: 17824954
Invasion of mosquito salivary glands by malaria parasites: prerequisites and defense strategies.
International journal for parasitology Sep, 2010 | Pubmed ID: 20621627
Continuous oral chloroquine as a novel route for Plasmodium prophylaxis and cure in experimental murine models.
BMC research notes , 2011 | Pubmed ID: 21798062
To go, or not to go, that is the question - six personal reflections on how geographic mobility may affect your career and life.
BioEssays : news and reviews in molecular, cellular and developmental biology Oct, 2011 | Pubmed ID: 21858845
In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway.
BMC microbiology , 2012 | Pubmed ID: 22694849
Natural transmission of Plasmodium berghei exacerbates chronic tuberculosis in an experimental co-infection model.
PloS one , 2012 | Pubmed ID: 23110184
Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agents.
ChemMedChem Mar, 2013 | Pubmed ID: 23341167
RNAi in Plasmodium.
Current pharmaceutical design , 2014 | Pubmed ID: 23701540
A primaquine-chloroquine hybrid with dual activity against Plasmodium liver and blood stages.
International journal of medical microbiology : IJMM Dec, 2013 | Pubmed ID: 23992634
The Spatiotemporal Dynamics and Membranous Features of the Plasmodium Liver Stage Tubovesicular Network.
Traffic (Copenhagen, Denmark) Jan, 2014 | Pubmed ID: 24423236
CD8(+) T Cells Mediate Robust Stage-Specific Immunity to P. berghei under Chemoprophylaxis and This Protective Environment Is Not Downregulated by the Presence of Blood-Stage Infection.
PloS one , 2014 | Pubmed ID: 24516592
CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox.
Biotechnology journal Nov, 2014 | Pubmed ID: 25186301
AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2014 | Pubmed ID: 25189739
Protection against malaria by immunization with non-attenuated sporozoites under single-dose piperaquine-tetraphosphate chemoprophylaxis.
Vaccine Oct, 2014 | Pubmed ID: 25203450
In vitro activity of wALADin benzimidazoles against different life cycle stages of Plasmodium parasites.
Antimicrobial agents and chemotherapy Jan, 2015 | Pubmed ID: 25313210
Plasmodium attenuation: connecting the dots between early immune responses and malaria disease severity.
Frontiers in microbiology , 2014 | Pubmed ID: 25520710
Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination.
Malaria journal Jan, 2015 | Pubmed ID: 25627880
Chemical attenuation of Plasmodium in the liver modulates severe malaria disease progression.
Journal of immunology (Baltimore, Md. : 1950) May, 2015 | Pubmed ID: 25862814
Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining.
Genome biology Nov, 2015 | Pubmed ID: 26573820
Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream.
PLoS pathogens Mar, 2016 | Pubmed ID: 26964100
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
The Lancet. Neurology May, 2016 | Pubmed ID: 27011339
Plasmodium meets AAV-the (un)likely marriage of parasitology and virology, and how to make the match.
FEBS letters Jul, 2016 | Pubmed ID: 27117587
Protective efficacy and safety of liver stage attenuated malaria parasites.
Scientific reports May, 2016 | Pubmed ID: 27241521
The Actin Filament-Binding Protein Coronin Regulates Motility in Plasmodium Sporozoites.
PLoS pathogens Jul, 2016 | Pubmed ID: 27409081
A suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infection.
FEBS open bio Aug, 2016 | Pubmed ID: 27516964
Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes.
Nature communications Nov, 2016 | Pubmed ID: 27824335
Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2017 | Pubmed ID: 28137845
Angelika Hoffmann1,2,
Xavier Helluy2,3,
Manuel Fischer2,
Ann-Kristin Mueller4,5,
Sabine Heiland2,
Mirko Pham1,6,
Martin Bendszus1,
Johannes Pfeil4,5,7
1Department of Neuroradiology, Heidelberg University Hospital,
2Division of Experimental Radiology, Department of Neuroradiology, Heidelberg University Hospital,
3NeuroImaging Centre Research, Department of Neuroscience, Ruhr-University Bochum,
4Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital,
5, German Centre for Infection Research (DZIF),
6Department of Neuroradiology, University of Würzburg,
7Center for Childhood and Adolescent Medicine, General Pediatrics, Heidelberg University Hospital
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