The protocol describes a rodent model of unfixed head mild traumatic brain injury induced by a weight drop allowing for free linear and rotational impact-related forces. The dynamics of this injury are similar to concussions that occur in humans and are useful to investigate underlying mechanisms involved in post-traumatic headache.
The present protocol describes the concepts and technical application of the tensometric myograph technique using a multi-chamber myograph system in the experimental ex vivo assessment of mouse aortic endothelial function.
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