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Otto-von-Guericke University

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

A Microfluidic Chip for ICPMS Sample Introduction

Pascal E. Verboket¹, Olga Borovinskaya¹, Nicole Meyer¹, Detlef Günther¹, Petra S. Dittrich¹

¹Department of Chemistry and Applied Biosciences, ETH Zurich

We present a discrete droplet sample introduction system for inductively coupled plasma mass spectrometry (ICPMS). It is based on a cheap and disposable microfluidic chip that generates highly monodisperse droplets in a size range of 40−60 µm at frequencies from 90 to 7,000 Hz.

Developmental Biology

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo

Nicole Meyer¹, Thomas Schüler², Ana Claudia Zenclussen¹

¹Experimental Obstetrics and Gynecology, Medical Faculty, Otto-von-Guericke University, ²Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University

Here we describe the technique of high frequency ultrasound for in vivo analysis of fetuses in mice. This method allows the follow-up of fetuses and the analysis of placental parameters as well as maternal and fetal blood flow throughout pregnancy.