Genetic Studies of Human DNA Repair Proteins Using Yeast as a Model System
March 18th, 2010
•Genetic studies in yeast can be employed to investigate the molecular and cellular functions of human genes in cellular DNA metabolism. Methods are described for the genetic characterization of the human WRN gene product defective in the premature aging disorder Werner syndrome in functionally conserved pathways using yeast as a tractable model system.
Tags
Vídeos Relacionados
Microinjection of Medaka Embryos for use as a Model Genetic Organism
Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique
Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
Generation of Human Cardiomyocytes: A Differentiation Protocol from Feeder-free Human Induced Pluripotent Stem Cells
Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
Real-time Imaging of Single Engineered RNA Transcripts in Living Cells Using Ratiometric Bimolecular Beacons
Genetic Barcoding with Fluorescent Proteins for Multiplexed Applications
Visualization of miniSOG Tagged DNA Repair Proteins in Combination with Electron Spectroscopic Imaging (ESI)
DNA Electroporation, Isolation and Imaging of Myofibers
Multi-enzyme Screening Using a High-throughput Genetic Enzyme Screening System
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados