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JoVE Journal

Medicine

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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain

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07:27 min

July 18th, 2016

July 18th, 2016

8,682 Views

0:05

Title

0:41

von Frey Test

1:40

Plantar Test

2:27

Collagenase Lesion Surgery

3:41

Radiotracer Injection

4:39

Brain Slicing

5:37

Results: ROI Analysis and Relationship Among Inter-regional Correlations Between Neural Substrates Involved in Central Post-stroke Pain

6:33

Conclusion

Transcrição

The overall goal of this experimental procedure is to assess the involvement of neural substrates of thalamic lesion induced central post-stroke pain using the radio isotope tracer method. This method can help answer key questions in which brain a

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We present a protocol to measure [14C]-iodoantipyrine (IAP) uptake and assess the activation of neural substrates that are involved in central post-stroke pain (CPSP) in a rodent model.

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