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JoVE Journal

Medicine

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Integrated Compensatory Responses in a Human Model of Hemorrhage

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07:57 min

November 20th, 2016

November 20th, 2016

12,347 Views

0:05

Title

1:11

Equipment & Subject Preparation

4:20

LBNP Experiment

6:34

Results: Changes in MAP, Heart Rate, and SpO2 Occur during Later Phases of Hemorrhage, While CRI Decreases Early

7:17

Conclusion

Transcrição

The overall goal of this procedure is to simulate central hypovolimia associated with hemorrhage in humans using lower-body negative pressure and to assess the individual's capacity to compensate during this challenge. Lower-body negative pressure

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The purpose of this protocol is to demonstrate the techniques for measuring compensatory responses to reduced central blood volume using lower body negative pressure as a noninvasive experimental model of human hemorrhage which can be used to quantify the total integration of compensatory mechanisms to blood volume deficit in humans.

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