Results: Purification and Immunohistochemistry of Amyloid-β42 in Adult Zebrafish Brain
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Conclusion
TRANSCRIÇÃO
The overall goal of this method is to synthesize amyloid beta 42 peptides and inject them into the adult zebrafish brain, to generate a particular model of Amyloid doses as seen in Alzheimer's disease. This method can help us to address important
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This protocol describes the synthesis, characterization, and injection of monomeric amyloid-β42 peptides for generating amyloid toxicity in adult zebrafish to establish an Alzheimer's disease model, followed by histological analyses and detection of aggregations.