Pre-Infusion Imaging: Transmission and Blank Image Acquisition
2:35
Post-Infusion Image Acquisition: Planar Image
3:21
Post-Infusion Image Acquisition: 3D SPECT/CT
3:51
Image Analysis
4:58
Blood Sample Measurements and Dosimetry Evaluation
5:50
Hybrid 2D+3D SCPET/CT Image Analysis
6:21
Adult Phantom Creation and Red Marrow Evaluation
7:50
Results: Representative Comparison of 2D, Hybrid 2D+3D, and 3D SPECT/CT Methods for Transient Intestine Uptake Overlap on Kidneys
8:35
Conclusion
TRANSCRIÇÃO
The method can be used in peptide-receptor radionuclide therapy and enable us to improve the accuracy of absorbed dose estimation in the presence of overlapping organs. The uptake distribution provided by the 3D SPECT/CT images is combined with th
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This method estimates the absorbed dose of different structures for peptide-receptor-radionuclide-therapy (PRRT) with the possibility of avoiding organ overlap on 2D-projections. Serial whole-body planar images permit estimation of mean absorbed doses along the whole body, while the hybrid approach, combining planar images and 3D-SPECT/CT image, overcomes the limitations of structure overlapping.