Laboratory of Retrovirology
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HIV-1-induced AIDS in monkeys.
Science (New York, N.Y.) Jun, 2014 | Pubmed ID: 24948736
Derivation of simian tropic HIV-1 infectious clone reveals virus adaptation to a new host.
Proceedings of the National Academy of Sciences of the United States of America May, 2019 | Pubmed ID: 31048506
Vesicular Stomatitis Virus Transcription Is Inhibited by TRIM69 in the Interferon-Induced Antiviral State.
Journal of virology Dec, 2019 | Pubmed ID: 31578292
Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection.
eLife Oct, 2019 | Pubmed ID: 31644426
Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.
bioRxiv : the preprint server for biology May, 2020 | Pubmed ID: 32511384
Convergent antibody responses to SARS-CoV-2 in convalescent individuals.
Nature Aug, 2020 | Pubmed ID: 32555388
Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies.
bioRxiv : the preprint server for biology May, 2020 | Pubmed ID: 32577645
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
bioRxiv : the preprint server for biology Jun, 2020 | Pubmed ID: 32577658
Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID19 Patients.
medRxiv : the preprint server for health sciences Sep, 2020 | Pubmed ID: 32577675
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell Aug, 2020 | Pubmed ID: 32645326
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses.
The Journal of experimental medicine Nov, 2020 | Pubmed ID: 32692348
Serological Assays Estimate Highly Variable SARS-CoV-2 Neutralizing Antibody Activity in Recovered COVID-19 Patients.
Journal of clinical microbiology Nov, 2020 | Pubmed ID: 32917729
Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection .
bioRxiv : the preprint server for biology Sep, 2020 | Pubmed ID: 32995782
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants.
eLife Oct, 2020 | Pubmed ID: 33112236
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo.
The Journal of experimental medicine Mar, 2021 | Pubmed ID: 33211088
Evolution of antibody immunity to SARS-CoV-2.
Nature Mar, 2021 | Pubmed ID: 33461210
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants.
Nature Apr, 2021 | Pubmed ID: 33567448
Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies.
bioRxiv : the preprint server for biology Mar, 2021 | Pubmed ID: 33758856
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies.
bioRxiv : the preprint server for biology Mar, 2021 | Pubmed ID: 33758864
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.
bioRxiv : the preprint server for biology Apr, 2021 | Pubmed ID: 33851164
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
bioRxiv : the preprint server for biology Apr, 2021 | Pubmed ID: 33948592
Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature Jul, 2021 | Pubmed ID: 34098567
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.
Nature Jul, 2021 | Pubmed ID: 34126625
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies.
Nature communications Jul, 2021 | Pubmed ID: 34234131
Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: implications for the ability of serological assays to predict immunity.
medRxiv : the preprint server for health sciences Jul, 2021 | Pubmed ID: 34268524
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity Aug, 2021 | Pubmed ID: 34331873
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell reports Sep, 2021 | Pubmed ID: 34534459
High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape.
Nature Dec, 2021 | Pubmed ID: 34544114
Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination.
Nature Dec, 2021 | Pubmed ID: 34619745
Replication and single-cycle delivery of SARS-CoV-2 replicons.
Science (New York, N.Y.) Nov, 2021 | Pubmed ID: 34648371
Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations.
Nature immunology Dec, 2021 | Pubmed ID: 34716452
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.
eLife Dec, 2021 | Pubmed ID: 34874007
Plasma neutralization properties of the SARS-CoV-2 Omicron variant.
medRxiv : the preprint server for health sciences Dec, 2021 | Pubmed ID: 34931199
Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.
bioRxiv : the preprint server for biology Feb, 2022 | Pubmed ID: 35132412
Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost.
Nature Jul, 2022 | Pubmed ID: 35447027
Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity Jun, 2022 | Pubmed ID: 35447092
Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: a serological analysis.
The Lancet. Microbe Jul, 2022 | Pubmed ID: 35636436
Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans.
The Journal of experimental medicine Aug, 2022 | Pubmed ID: 35776090
Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization After Messenger RNA Vaccination and Variant Breakthrough Infection.
Open forum infectious diseases Jul, 2022 | Pubmed ID: 35818364
Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.
Gut microbes , 2022 | Pubmed ID: 35915556
Antibody feedback regulation of memory B cell development in SARS-CoV-2 mRNA vaccination.
medRxiv : the preprint server for health sciences Aug, 2022 | Pubmed ID: 35982682
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape.
bioRxiv : the preprint server for biology Aug, 2022 | Pubmed ID: 36032981
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans.
The Journal of experimental medicine Dec, 2022 | Pubmed ID: 36149398
Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination.
Nature Jan, 2023 | Pubmed ID: 36473496
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape.
Nature communications Jan, 2023 | Pubmed ID: 36653360
Harald Hartweger1,
Rajeev Gautam2,
Yoshiaki Nishimura2,
Fabian Schmidt3,5,
Kai-Hui Yao1,
Amelia Escolano1,6,
Mila Jankovic1,
Malcolm A. Martin2,
Michel C. Nussenzweig1,4
1Laboratory of Molecular Immunology, The Rockefeller University,
2Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health,
3Laboratory of Retrovirology, The Rockefeller University,
4Howard Hughes Medical Institute, The Rockefeller University,
5Laboratory of Applied Virology and Precision Medicine, King Abdullah University of Science and Technology (KAUST),
6Vaccine and Immunotherapy Center, Wistar Institute
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