Department of Pathology
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Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity.
Genetics Jan, 2002 | Pubmed ID: 11805047
Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity.
Molecular biology of the cell Apr, 2002 | Pubmed ID: 11950950
AGEID: a database of aging genes and interventions.
Mechanisms of ageing and development Apr, 2002 | Pubmed ID: 12044961
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.
Nature Jul, 2002 | Pubmed ID: 12124627
High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction.
Molecular and cellular biology Nov, 2002 | Pubmed ID: 12391171
Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism.
Genetics Apr, 2004 | Pubmed ID: 15126388
Sir2-independent life span extension by calorie restriction in yeast.
PLoS biology Sep, 2004 | Pubmed ID: 15328540
Aging-related research in the "-omics" age.
Science of aging knowledge environment : SAGE KE Oct, 2004 | Pubmed ID: 15498757
Large-scale identification in yeast of conserved ageing genes.
Mechanisms of ageing and development Jan, 2005 | Pubmed ID: 15610758
Substrate-specific activation of sirtuins by resveratrol.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15684413
Genes determining yeast replicative life span in a long-lived genetic background.
Mechanisms of ageing and development Apr, 2005 | Pubmed ID: 15722108
The enigmatic role of Sir2 in aging.
Cell Nov, 2005 | Pubmed ID: 16286003
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science (New York, N.Y.) Nov, 2005 | Pubmed ID: 16293764
Increased life span due to calorie restriction in respiratory-deficient yeast.
PLoS genetics Nov, 2005 | Pubmed ID: 16311627
Extension of chronological life span in yeast by decreased TOR pathway signaling.
Genes & development Jan, 2006 | Pubmed ID: 16418483
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".
Science (New York, N.Y.) Jun, 2006 | Pubmed ID: 16741098
Genome-wide approaches to understanding human ageing.
Human genomics Jun, 2006 | Pubmed ID: 16848980
Lifespan extension in Caenorhabditis elegans by complete removal of food.
Aging cell Dec, 2006 | Pubmed ID: 17081160
Medicine: grapes versus gluttony.
Nature Nov, 2006 | Pubmed ID: 17086197
Genome-wide identification of conserved longevity genes in yeast and worms.
Mechanisms of ageing and development Jan, 2007 | Pubmed ID: 17126379
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.
Aging cell Dec, 2006 | Pubmed ID: 17129213
The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function.
Genetics Jan, 2007 | Pubmed ID: 17151231
Sir2 and calorie restriction in yeast: a skeptical perspective.
Ageing research reviews Aug, 2007 | Pubmed ID: 17512264
Recent developments in yeast aging.
PLoS genetics May, 2007 | Pubmed ID: 17530929
Does resveratrol activate yeast Sir2 in vivo?
Aging cell Aug, 2007 | Pubmed ID: 17635418
Molecular basis of ageing.
EMBO reports Oct, 2007 | Pubmed ID: 17823613
Protein translation, 2007.
Aging cell Dec, 2007 | Pubmed ID: 17941970
Single-gene deletions that restore mating competence to diploid yeast.
FEMS yeast research Mar, 2008 | Pubmed ID: 17995956
Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes.
Experimental gerontology Mar, 2008 | Pubmed ID: 18083317
A method for high-throughput quantitative analysis of yeast chronological life span.
The journals of gerontology. Series A, Biological sciences and medical sciences Feb, 2008 | Pubmed ID: 18314444
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans.
Aging cell Jun, 2008 | Pubmed ID: 18331616
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.
Genome research Apr, 2008 | Pubmed ID: 18340043
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell Apr, 2008 | Pubmed ID: 18423200
The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America.
The journals of gerontology. Series A, Biological sciences and medical sciences Apr, 2008 | Pubmed ID: 18426956
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.
BMC developmental biology , 2008 | Pubmed ID: 18457595
The ongoing saga of sirtuins and aging.
Cell metabolism Jul, 2008 | Pubmed ID: 18590685
Longevity genomics across species.
Current genomics Apr, 2007 | Pubmed ID: 18660849
Cell biology: A molecular age barrier.
Nature Aug, 2008 | Pubmed ID: 18685697
Protein translation, 2008.
Aging cell Dec, 2008 | Pubmed ID: 18782345
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity.
PloS one , 2008 | Pubmed ID: 19030232
A molecular mechanism of chronological aging in yeast.
Cell cycle (Georgetown, Tex.) Apr, 2009 | Pubmed ID: 19305133
Proteasomal regulation of the hypoxic response modulates aging in C. elegans.
Science (New York, N.Y.) May, 2009 | Pubmed ID: 19372390
Histone H4 lysine 16 acetylation regulates cellular lifespan.
Nature Jun, 2009 | Pubmed ID: 19516333
A genomic approach to yeast chronological aging.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19521821
The TOR pathway comes of age.
Biochimica et biophysica acta Oct, 2009 | Pubmed ID: 19539012
Ageing: A midlife longevity drug?
Nature Jul, 2009 | Pubmed ID: 19606132
The hypoxic response and aging.
Cell cycle (Georgetown, Tex.) Aug, 2009 | Pubmed ID: 19633411
Hot topics in aging research: protein translation, 2009.
Aging cell Dec, 2009 | Pubmed ID: 19747234
Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.
The journals of gerontology. Series A, Biological sciences and medical sciences Dec, 2009 | Pubmed ID: 19776218
Cell signaling. Aging is RSKy business.
Science (New York, N.Y.) Oct, 2009 | Pubmed ID: 19797648
Spermidine surprise for a long life.
Nature cell biology Nov, 2009 | Pubmed ID: 19884883
Resveratrol and rapamycin: are they anti-aging drugs?
BioEssays : news and reviews in molecular, cellular and developmental biology Feb, 2010 | Pubmed ID: 20091754
YODA: software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast.
BMC bioinformatics , 2010 | Pubmed ID: 20298554
Lessons on longevity from budding yeast.
Nature Mar, 2010 | Pubmed ID: 20336133
A role for SIRT1 in the hypoxic response.
Molecular cell Jun, 2010 | Pubmed ID: 20620950
The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging.
Biological chemistry Oct, 2010 | Pubmed ID: 20707608
Regulation of mRNA translation as a conserved mechanism of longevity control.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20886753
Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix.
Aging cell Feb, 2011 | Pubmed ID: 21108727
Hot topics in aging research: protein translation and TOR signaling, 2010.
Aging cell Apr, 2011 | Pubmed ID: 21176090
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast.
Cell cycle (Georgetown, Tex.) Jan, 2011 | Pubmed ID: 21191185
HIF-1 modulates longevity and healthspan in a temperature-dependent manner.
Aging cell Apr, 2011 | Pubmed ID: 21241450
A genomic analysis of chronological longevity factors in budding yeast.
Cell cycle (Georgetown, Tex.) May, 2011 | Pubmed ID: 21447998
Trinations aging symposium.
Mechanisms of ageing and development Jun-Jul, 2011 | Pubmed ID: 21771608
Sir2 deletion prevents lifespan extension in 32 long-lived mutants.
Aging cell Dec, 2011 | Pubmed ID: 21902802
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.
PLoS genetics Sep, 2011 | Pubmed ID: 21931558
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Nature Sep, 2011 | Pubmed ID: 21938067
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast.
PloS one , 2011 | Pubmed ID: 21949725
Genome-wide analysis of yeast aging.
Sub-cellular biochemistry , 2012 | Pubmed ID: 22094426
The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans.
PloS one , 2011 | Pubmed ID: 22132200
A new chronological survival assay in mammalian cell culture.
Cell cycle (Georgetown, Tex.) Jan, 2012 | Pubmed ID: 22214665
Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae.
Genetics May, 2012 | Pubmed ID: 22377630
Midlife gene expressions identify modulators of aging through dietary interventions.
Proceedings of the National Academy of Sciences of the United States of America May, 2012 | Pubmed ID: 22509016
Replicative and chronological aging in Saccharomyces cerevisiae.
Cell metabolism Jul, 2012 | Pubmed ID: 22768836
Yeast as a model to understand the interaction between genotype and the response to calorie restriction.
FEBS letters Aug, 2012 | Pubmed ID: 22828279
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Science translational medicine Jul, 2012 | Pubmed ID: 22837538
pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast.
Cell cycle (Georgetown, Tex.) Aug, 2012 | Pubmed ID: 22871733
Elevated MTORC1 signaling and impaired autophagy.
Autophagy Jan, 2013 | Pubmed ID: 23064282
Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.
Aging cell Feb, 2013 | Pubmed ID: 23167605
Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae.
Experimental gerontology Oct, 2013 | Pubmed ID: 23235143
mTOR is a key modulator of ageing and age-related disease.
Nature Jan, 2013 | Pubmed ID: 23325216
End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging.
FEMS yeast research May, 2013 | Pubmed ID: 23336757
Life-span extension from hypoxia in Caenorhabditis elegans requires both HIF-1 and DAF-16 and is antagonized by SKN-1.
The journals of gerontology. Series A, Biological sciences and medical sciences Oct, 2013 | Pubmed ID: 23419779
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.
PLoS genetics , 2013 | Pubmed ID: 23505383
Longevity and aging.
F1000prime reports , 2013 | Pubmed ID: 23513177
Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans.
Current genomics Nov, 2012 | Pubmed ID: 23633911
Molecular mechanisms underlying genotype-dependent responses to dietary restriction.
Aging cell Jul, 2013 | Pubmed ID: 23837470
The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.
PLoS genetics , 2013 | Pubmed ID: 23990801
Yeast replicative aging: a paradigm for defining conserved longevity interventions.
FEMS yeast research Feb, 2014 | Pubmed ID: 24119093
Preserving youth: does rapamycin deliver?
Science translational medicine Nov, 2013 | Pubmed ID: 24225941
Deciphering the role of natural variation in age-related protein homeostasis.
BMC biology Sep, 2013 | Pubmed ID: 24228595
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.
Science (New York, N.Y.) Dec, 2013 | Pubmed ID: 24231806
UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin.
PloS one , 2013 | Pubmed ID: 24340038
mTOR Inhibition: From Aging to Autism and Beyond.
Scientifica , 2013 | Pubmed ID: 24379984
Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response.
PLoS genetics Jan, 2014 | Pubmed ID: 24391512
Development. Chemical warfare in the battle of the sexes.
Science (New York, N.Y.) Jan, 2014 | Pubmed ID: 24482469
Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase.
Mechanisms of ageing and development Jun, 2014 | Pubmed ID: 24486555
The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?
Experimental gerontology Aug, 2014 | Pubmed ID: 24518875
Buffering the pH of the culture medium does not extend yeast replicative lifespan.
F1000Research , 2013 | Pubmed ID: 24555104
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans.
Nature communications Mar, 2014 | Pubmed ID: 24662282
Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.
Longevity & healthspan , 2012 | Pubmed ID: 24764514
Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
Cell metabolism Jun, 2014 | Pubmed ID: 24814484
Rejuvenation: it's in our blood.
Cell metabolism Jul, 2014 | Pubmed ID: 24988454
The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction.
Cell reports Jul, 2014 | Pubmed ID: 25043177
A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer.
Disease models & mechanisms Oct, 2014 | Pubmed ID: 25085991
Replicative life span analysis in budding yeast.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25213254
Rapamycin and ageing: when, for how long, and how much?
Journal of genetics and genomics = Yi chuan xue bao Sep, 2014 | Pubmed ID: 25269671
Modulating mTOR in aging and health.
Interdisciplinary topics in gerontology , 2015 | Pubmed ID: 25341517
Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism.
Oncotarget Jan, 2015 | Pubmed ID: 25415049
Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import.
PLoS genetics Dec, 2014 | Pubmed ID: 25521617
Fertile waters for aging research.
Cell Feb, 2015 | Pubmed ID: 25723160
Why is aging conserved and what can we do about it?
PLoS biology Apr, 2015 | Pubmed ID: 25923592
PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae.
Age (Dordrecht, Netherlands) Jun, 2015 | Pubmed ID: 25936926
MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.
Mutation research Jul, 2015 | Pubmed ID: 25983189
The Biology of Aging: Citizen Scientists and Their Pets as a Bridge Between Research on Model Organisms and Human Subjects.
Veterinary pathology Mar, 2016 | Pubmed ID: 26077786
H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Genes & development Jul, 2015 | Pubmed ID: 26159996
Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice.
Frontiers in genetics , 2015 | Pubmed ID: 26257774
Transcription errors induce proteotoxic stress and shorten cellular lifespan.
Nature communications Aug, 2015 | Pubmed ID: 26304740
Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals "aging factors" and mechanism of lifespan asymmetry.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2015 | Pubmed ID: 26351681
Searching for the elusive mitochondrial longevity signal in C. elegans.
Worm Jul-Sep, 2014 | Pubmed ID: 26430544
A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.
Cell metabolism Nov, 2015 | Pubmed ID: 26456335
Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2015 | Pubmed ID: 26504246
Biochemical Genetic Pathways that Modulate Aging in Multiple Species.
Cold Spring Harbor perspectives in medicine Nov, 2015 | Pubmed ID: 26525455
Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans.
Frontiers in genetics , 2015 | Pubmed ID: 26579191
Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span.
Science (New York, N.Y.) Dec, 2015 | Pubmed ID: 26586189
Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae.
Aging cell Apr, 2016 | Pubmed ID: 26762766
Healthy aging: The ultimate preventative medicine.
Science (New York, N.Y.) Dec, 2015 | Pubmed ID: 26785476
Microfluidic technologies for yeast replicative lifespan studies.
Mechanisms of ageing and development 01, 2017 | Pubmed ID: 27015709
Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates.
NPJ aging and mechanisms of disease , 2015 | Pubmed ID: 27030810
The dog aging project: translational geroscience in companion animals.
Mammalian genome : official journal of the International Mammalian Genome Society 08, 2016 | Pubmed ID: 27143112
New functional and biophysical insights into the mitochondrial Rieske iron-sulfur protein from genetic suppressor analysis in C. elegans.
Worm Apr-Jun, 2016 | Pubmed ID: 27383074
New insights into cell non-autonomous mechanisms of the C. elegans hypoxic response.
Worm Apr-Jun, 2016 | Pubmed ID: 27383456
Rapamycin in aging and disease: maximizing efficacy while minimizing side effects.
Oncotarget Jul, 2016 | Pubmed ID: 27384492
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.
eLife 08, 2016 | Pubmed ID: 27549339
Age-associated vulval integrity is an important marker of nematode healthspan.
Age (Dordrecht, Netherlands) Dec, 2016 | Pubmed ID: 27566309
Rapamycin enhances survival in a Drosophila model of mitochondrial disease.
Oncotarget Dec, 2016 | Pubmed ID: 27741510
Dietary restriction and lifespan: Lessons from invertebrate models.
Ageing research reviews Oct, 2017 | Pubmed ID: 28007498
CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes.
Cell reports Feb, 2017 | Pubmed ID: 28228255
Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments.
Alzheimer's & dementia : the journal of the Alzheimer's Association Oct, 2017 | Pubmed ID: 28242297
Asymptomatic heart valve dysfunction in healthy middle-aged companion dogs and its implications for cardiac aging.
GeroScience 02, 2017 | Pubmed ID: 28299636
Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.
PLoS genetics Mar, 2017 | Pubmed ID: 28355222
Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans.
The journals of gerontology. Series A, Biological sciences and medical sciences Aug, 2017 | Pubmed ID: 28369388
A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.
GeroScience 04, 2017 | Pubmed ID: 28374166
Flavin-containing monooxygenases in aging and disease: Emerging roles for ancient enzymes.
The Journal of biological chemistry 07, 2017 | Pubmed ID: 28515321
Inter-organ regulation of haem homeostasis.
Nature cell biology Jun, 2017 | Pubmed ID: 28659637
A system to identify inhibitors of mTOR signaling using high-resolution growth analysis in Saccharomyces cerevisiae.
GeroScience Aug, 2017 | Pubmed ID: 28707282
Rapamycin treatment attenuates age-associated periodontitis in mice.
GeroScience Aug, 2017 | Pubmed ID: 28889220
Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.
Frontiers in genetics , 2017 | Pubmed ID: 28919908
Genetic interaction with temperature is an important determinant of nematode longevity.
Aging cell 12, 2017 | Pubmed ID: 28940623
Electrophysiological Measures of Aging Pharynx Function in C. elegans Reveal Enhanced Organ Functionality in Older, Long-lived Mutants.
The journals of gerontology. Series A, Biological sciences and medical sciences Jul, 2019 | Pubmed ID: 29165668
Oral health in geroscience: animal models and the aging oral cavity.
GeroScience 02, 2018 | Pubmed ID: 29282653
Corrigendum: Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.
Frontiers in genetics , 2017 | Pubmed ID: 29285026
The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells.
Current opinion in systems biology Apr, 2018 | Pubmed ID: 29552673
Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in .
eLife 08, 2018 | Pubmed ID: 30070633
How healthy is the healthspan concept?
GeroScience 08, 2018 | Pubmed ID: 30084059
Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2018 | Pubmed ID: 30185560
Research to Promote Longevity and Health Span in Companion Dogs: A Pediatric Perspective.
The American journal of bioethics : AJOB Oct, 2018 | Pubmed ID: 30339074
mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases.
Kidney international 02, 2019 | Pubmed ID: 30471880
Rapamycin and Alzheimer's disease: Time for a clinical trial?
Science translational medicine 01, 2019 | Pubmed ID: 30674654
Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 02, 2019 | Pubmed ID: 30718408
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics.
eLife 06, 2019 | Pubmed ID: 31157618
In vivo measurements reveal a single 5'-intron is sufficient to increase protein expression level in Caenorhabditis elegans.
Scientific reports Jun, 2019 | Pubmed ID: 31235724
Phenotypic and Genotypic Consequences of CRISPR/Cas9 Editing of the Replication Origins in the rDNA of .
Genetics 09, 2019 | Pubmed ID: 31292210
Trajectories of Aging: How Systems Biology in Yeast Can Illuminate Mechanisms of Personalized Aging.
Proteomics Aug, 2019 | Pubmed ID: 31385433
An inexpensive microscopy system for microfluidic studies in budding yeast.
Translational medicine of aging , 2019 | Pubmed ID: 31511839
Cross species application of quantitative neuropathology assays developed for clinical Alzheimer's disease samples.
Pathobiology of aging & age related diseases , 2019 | Pubmed ID: 31528297
DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging.
eLife 11, 2019 | Pubmed ID: 31714209
WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans.
GeroScience 12, 2019 | Pubmed ID: 31728898
Latest advances in aging research and drug discovery.
Aging 11, 2019 | Pubmed ID: 31770722
Desexing Dogs: A Review of the Current Literature.
Animals : an open access journal from MDPI Dec, 2019 | Pubmed ID: 31817504
Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins.
Nature communications 12, 2019 | Pubmed ID: 31844058
Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae.
GeroScience Jan, 2020 | Pubmed ID: 31975050
The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast.
Biochimica et biophysica acta. Biomembranes Mar, 2020 | Pubmed ID: 32145284
DDS promotes longevity through a microbiome-mediated starvation signal.
Translational medicine of aging , 2019 | Pubmed ID: 32190786
Rb analog Whi5 regulates G1 to S transition and cell size but not replicative lifespan in budding yeast.
Translational medicine of aging , 2019 | Pubmed ID: 32190787
Translational geroscience: A new paradigm for 21 century medicine.
Translational medicine of aging Oct, 2017 | Pubmed ID: 32219192
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