Intracellular Membrane Trafficking Unit,
Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research,
Laboratory of Cellular and Molecular Biology,
Center for Cancer Research,
National Cancer Institute,
Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research,
Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute
Roberto Weigert has not added Biography.
If you are Roberto Weigert and would like to personalize this page please email our Author Liaison for assistance.
Convergence of non-clathrin- and clathrin-derived endosomes involves Arf6 inactivation and changes in phosphoinositides.
Molecular biology of the cell Feb, 2003 | Pubmed ID: 12589044
A role for Arf1 in mitotic Golgi disassembly, chromosome segregation, and cytokinesis.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2003 | Pubmed ID: 14585930
Characterization of a nonclathrin endocytic pathway: membrane cargo and lipid requirements.
Molecular biology of the cell Aug, 2004 | Pubmed ID: 15146059
Rab22a regulates the recycling of membrane proteins internalized independently of clathrin.
Molecular biology of the cell Aug, 2004 | Pubmed ID: 15181155
Multiple activities for Arf1 at the Golgi complex.
Biochimica et biophysica acta Jul, 2005 | Pubmed ID: 15979507
Fluorescent microscopy-based assays to study the role of Rab22a in clathrin-independent endocytosis.
Methods in enzymology , 2005 | Pubmed ID: 16473591
Intravital two-photon microscopy for studying the uptake and trafficking of fluorescently conjugated molecules in live rodents.
Traffic (Copenhagen, Denmark) Sep, 2008 | Pubmed ID: 18647170
Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery.
ACS nano Feb, 2009 | Pubmed ID: 19236065
A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability.
Molecular and cellular biology May, 2009 | Pubmed ID: 19255141
Discovery of new cargo proteins that enter cells through clathrin-independent endocytosis.
Traffic (Copenhagen, Denmark) May, 2009 | Pubmed ID: 19302270
The effect of hypusine modification on the intracellular localization of eIF5A.
Biochemical and biophysical research communications Jun, 2009 | Pubmed ID: 19379712
Myosin Vc is a molecular motor that functions in secretory granule trafficking.
Molecular biology of the cell Nov, 2009 | Pubmed ID: 19741097
Expression of plasmid DNA in the salivary gland epithelium: novel approaches to study dynamic cellular processes in live animals.
American journal of physiology. Cell physiology Dec, 2009 | Pubmed ID: 19794147
Intravital microscopy: a novel tool to study cell biology in living animals.
Histochemistry and cell biology May, 2010 | Pubmed ID: 20372919
Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras.
Molecular and cellular biology Jun, 2010 | Pubmed ID: 20385769
Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome.
Nature genetics Aug, 2010 | Pubmed ID: 20657595
Intravital microscopy as a tool to study drug delivery in preclinical studies.
Advanced drug delivery reviews Jan-Feb, 2011 | Pubmed ID: 20933026
Cyclooxygenase-1 is involved in the inhibition of hippocampal neurogenesis after lipopolysaccharide-induced neuroinflammation.
Cell cycle (Georgetown, Tex.) Aug, 2011 | Pubmed ID: 21694498
The cyclooxygenase-2 pathway via the PGEâ‚‚ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination.
Journal of neurochemistry May, 2012 | Pubmed ID: 21699540
Role for the actomyosin complex in regulated exocytosis revealed by intravital microscopy.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21808006
A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells.
Science signaling Sep, 2011 | Pubmed ID: 21934106
Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer.
Cancer research Nov, 2011 | Pubmed ID: 21975930
Regulated exocytosis: novel insights from intravital microscopy.
Traffic (Copenhagen, Denmark) May, 2012 | Pubmed ID: 22243493
Linking differences in membrane tension with the requirement for a contractile actomyosin scaffold during exocytosis in salivary glands.
Communicative & integrative biology Jan, 2012 | Pubmed ID: 22482019
Plasmid DNA is internalized from the apical plasma membrane of the salivary gland epithelium in live animals.
Histochemistry and cell biology Aug, 2012 | Pubmed ID: 22544351
Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22753477
Homeostasis of the apical plasma membrane during regulated exocytosis in the salivary glands of live rodents.
Bioarchitecture Sep, 2011 | Pubmed ID: 22754613
Multiple roles for the actin cytoskeleton during regulated exocytosis.
Cellular and molecular life sciences : CMLS Jun, 2013 | Pubmed ID: 22986507
Intravital microscopy: A practical guide on imaging intracellular structures in live animals.
Bioarchitecture Sep, 2012 | Pubmed ID: 22992750
Intravital microscopy to image membrane trafficking in live rats.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23027003
Rab25 regulates invasion and metastasis in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2013 | Pubmed ID: 23340300
Imaging cell biology in live animals: ready for prime time.
The Journal of cell biology Jun, 2013 | Pubmed ID: 23798727
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.
The Journal of cell biology Sep, 2013 | Pubmed ID: 24019537
Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor.
Nature medicine Oct, 2013 | Pubmed ID: 24056772
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
The Journal of clinical investigation Dec, 2013 | Pubmed ID: 24177428
Endosomes derived from clathrin-independent endocytosis serve as precursors for endothelial lumen formation.
PloS one , 2013 | Pubmed ID: 24282620
Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis.
Current biology : CB Mar, 2014 | Pubmed ID: 24613307
Imaging the dynamics of endocytosis in live mammalian tissues.
Cold Spring Harbor perspectives in biology Apr, 2014 | Pubmed ID: 24691962
Two-photon excitation improves multifocal structured illumination microscopy in thick scattering tissue.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2014 | Pubmed ID: 24706872
Intravital Microscopy Reveals Differences in the Kinetics of Endocytic Pathways between Cell Cultures and Live Animals.
Cells Nov, 2012 | Pubmed ID: 24710546
Probing the role of the actin cytoskeleton during regulated exocytosis by intravital microscopy.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24947398
Altered endosome biogenesis in prostate cancer has biomarker potential.
Molecular cancer research : MCR Dec, 2014 | Pubmed ID: 25080433
In vivo tissue-wide synchronization of mitochondrial metabolic oscillations.
Cell reports Oct, 2014 | Pubmed ID: 25373899
SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2015 | Pubmed ID: 25466898
Polyethylenimine-mediated expression of transgenes in the acinar cells of rats salivary glands in vivo.
Frontiers in cell and developmental biology , 2014 | Pubmed ID: 25621283
RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.
Nature communications Apr, 2015 | Pubmed ID: 25857352
Imaging membrane remodeling during regulated exocytosis in live mice.
Experimental cell research Oct, 2015 | Pubmed ID: 26160452
Arp2/3-mediated F-actin formation controls regulated exocytosis in vivo.
Nature communications Dec, 2015 | Pubmed ID: 26639106
A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.
Blood Mar, 2016 | Pubmed ID: 26647393
Toward in vivo two-photon analysis of mouse aqueous outflow structure and function.
Experimental eye research 05, 2017 | Pubmed ID: 27179411
Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo.
Hepatology (Baltimore, Md.) 10, 2016 | Pubmed ID: 27396550
Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β.
Molecular cell Nov, 2016 | Pubmed ID: 27746021
Sinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow.
The Journal of clinical investigation 12, 2016 | Pubmed ID: 27820703
Kinetics of milk lipid droplet transport, growth, and secretion revealed by intravital imaging: lipid droplet release is intermittently stimulated by oxytocin.
Molecular biology of the cell Apr, 2017 | Pubmed ID: 28179456
A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule.
Cell systems 03, 2017 | Pubmed ID: 28330614
Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.
The Journal of cell biology 07, 2017 | Pubmed ID: 28600434
Non-invasive intravital imaging of head and neck squamous cell carcinomas in live mice.
Methods (San Diego, Calif.) 09, 2017 | Pubmed ID: 28780320
ER/Golgi trafficking is facilitated by unbranched actin filaments containing Tpm4.2.
Cytoskeleton (Hoboken, N.J.) Oct, 2017 | Pubmed ID: 28834398
Isoform-specific roles of NMII drive membrane remodeling in vivo.
Cell cycle (Georgetown, Tex.) 10, 2017 | Pubmed ID: 28937881
Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake.
Cell reports 12, 2017 | Pubmed ID: 29281816
Parallel assembly of actin and tropomyosin, but not myosin II, during actin filament formation in live mice.
Journal of cell science 03, 2018 | Pubmed ID: 29487177
ONC201 kills breast cancer cells by targeting mitochondria.
Oncotarget Apr, 2018 | Pubmed ID: 29719618
The Actomyosin Cytoskeleton Drives Micron-Scale Membrane Remodeling In Vivo Via the Generation of Mechanical Forces to Balance Membrane Tension Gradients.
BioEssays : news and reviews in molecular, cellular and developmental biology 09, 2018 | Pubmed ID: 30080263
Symposium review: Intravital imaging of the lactating mammary gland in live mice reveals novel aspects of milk-lipid secretion.
Journal of dairy science Mar, 2019 | Pubmed ID: 30471915
Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals.
Molecular biology of the cell 02, 2019 | Pubmed ID: 30540520
Mitochondrial Populations Exhibit Differential Dynamic Responses to Increased Energy Demand during Exocytosis In Vivo.
iScience Jan, 2019 | Pubmed ID: 30661001
Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7.
Frontiers in immunology , 2019 | Pubmed ID: 30891040
Intravital microscopy in mammalian multicellular organisms.
Current opinion in cell biology 08, 2019 | Pubmed ID: 31125832
Dynamic polyhedral actomyosin lattices remodel micron-scale curved membranes during exocytosis in live mice.
Nature cell biology 08, 2019 | Pubmed ID: 31358965
Nanoarchitecture and dynamics of the mouse enteric glycocalyx examined by freeze-etching electron tomography and intravital microscopy.
Communications biology 01, 2020 | Pubmed ID: 31925335
Cdc42 controls secretory granules morphology in rodent salivary glands in vivo.
Communicative & integrative biology , 2020 | Pubmed ID: 32128025
A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.
Molecular biology of the cell 05, 2020 | Pubmed ID: 32213122
The LTB4-BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation.
The Journal of cell biology 10, 2020 | Pubmed ID: 32854115
Collective cancer cell invasion requires RNA accumulation at the invasive front.
Proceedings of the National Academy of Sciences of the United States of America 11, 2020 | Pubmed ID: 33060293
Transduction of Salivary Gland Acinar Cells with a Novel AAV Vector 44.9.
Molecular therapy. Methods & clinical development Dec, 2020 | Pubmed ID: 33294494
Calcineurin inhibitors suppress acute graft-versus-host disease via NFAT-independent inhibition of T cell receptor signaling.
The Journal of clinical investigation 06, 2021 | Pubmed ID: 33822776
Method for Acute Intravital Imaging of the Large Intestine in Live Mice.
Methods in molecular biology (Clifton, N.J.) , 2021 | Pubmed ID: 34028723
The butyrophilin 1a1 knockout mouse revisited: Ablation of leads to concurrent cell death and renewal in the mammary epithelium during lactation.
FASEB bioAdvances Dec, 2021 | Pubmed ID: 34938960
1Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch National Institute of Dental and Craniofacial Research, National Institutes of Health,
2Department of Biology, University of North Carolina at Chapel Hill ,
3Department of Chemical & Biochemical Engineering and Department of Biomedical Engineering, Rutgers University
Yeap Ng1,
Andrius Masedunskas1,2,
Marco Heydecker1,
Seham Ebrahim1,3,
Roberto Weigert1,
Ian H. Mather1
1Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health,
2Charles Perkins Centre, Central Clinical School, Faculty of Medicine and Health, The University of Sydney,
3Department of Molecular Physiology and Biological Physics, School of Medicine, University of Virginia
JoVE Hakkında
Telif Hakkı © 2020 MyJove Corporation. Tüm hakları saklıdır