University of Turku and Åbo Akademi University
2 ARTICLES PUBLISHED IN JoVE
Biochemistry
Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
Mahlet Z. Tamirat 1, Kari J. Kurppa 2, Klaus Elenius 2,3,4, Mark S. Johnson 1
1Structural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 2Medicity Research Laboratories and Institute of Biomedicine, University of Turku, 3Turku Bioscience Centre, University of Turku and Åbo Akademi University, 4Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital
The objective of this protocol is to use molecular dynamics simulations to examine the dynamic structural changes that occur due to activating mutations of the EGFR kinase protein.
Medicine
High-speed Video Microscopy Analysis for First-line Diagnosis of Primary Ciliary Dyskinesia
Rüdiger Schultz 1,2, Tiina Peromaa 3, Heikki Lukkarinen 2, Varpu Elenius 2
1Allergy Centre, Tampere University Hospital, 2Department of Pediatrics, Turku University Hospital, 3Turku Bioscience Center, University of Turku and Åbo Akademi University
High-speed video microscopy analysis is a relatively easy-to-perform, fast, cost-effective, and, in experienced hands, a considerably reliable tool for first-line diagnostics of primary ciliary dyskinesia, which should be available in every center involved in diagnostics and the treatment of severe lung diseases.
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