Results: Shear Rings Effectively Create Unidirectional and Periodic Shear Stress
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Conclusion
Transkript
The overall goal of this model is to create a simple and economical method for In Vitro periodic fluid flow, and shear stress studies on endothelial cells. This method can help answer key questions in the field of Endothelial Cell Physiology. Such
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Different levels and patterns of fluid shear are known to modulate endothelial gene expression, phenotype and susceptibility to disease. We discuss the assembly and use of 'shear rings': a model that produces unidirectional, periodic shear stress patterns. Shear rings are simple to assemble, economical and can produce high cell yields.