Results: Gel-seq Compared with Conventional Methods
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Conclusion
Transkript
The overall goal of this experiment is to generate next generation sequencing libraries from both the DNA and RNA of small populations of cells without splitting the sample at any point. This method provides researchers with a new approach to stud
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Gel-seq enables researchers to simultaneously prepare libraries for both DNA- and RNA-seq at negligible added cost starting from 100 - 1000 cells using a simple hydrogel device. This paper presents a detailed approach for the fabrication of the device as well as the biological protocol to generate paired libraries.