Results: Key Features of Genetic Manipulations of Mammary Epithelial Cells Based on Intraductal Injection of Ad-Cre
5:25
Conclusion
Transkript
This protocol will help researchers generate a new type of mouse model to recapitulate human breast cancer development from different subsets of mammary epithelial cells. This technique allows researchers to generate breast cancer mouse models in
Bu içeriğe erişmek için giriş yapın veya ücretsiz denemenizi başlatın
The goal of this protocol is to describe a new breast cancer modeling approach based on the intraductal injection of Cre-expressing adenovirus into mouse mammary glands. This approach allows both cell-type- and organ-specific manipulation of oncogenic events in a temporally controlled manner.