Capacitive Immunoprobe Fabrication and Functionalization
3:24
Experimental Setup for In Vitro Detection and Measurement of Peptide
4:41
Adaptation of the Capacitive Immunoprobe for In Vivo Use
5:56
Results: Assessment of Capacitive Immunoprobe
Transkript
This is the first time a method has been developed for the time-resolved measurement of peptide transmitter levels in vivo. We can measure peptide transmitter levels in single subjects and discrete locations with near-realtime analysis. First, cut
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Established immunochemical methods to measure peptide transmitters in vivo rely on microdialysis or bulk fluid draw to obtain the sample for offline analysis. However, these suffer from spatiotemporal limitations. The present protocol describes the fabrication and application of a capacitive immunoprobe biosensor that overcomes the limitations of the existing techniques.