Ole Isacson: Development of New Therapies for Parkinson's Disease

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23:53 min

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April 29th, 2007

DOI :

April 29th, 2007

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¹McLean Hospital, Harvard Stem Cell Institute, Harvard Medical School

Summary

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A Renowned Scientist

Is Dedicated To The Development Of New Therapies For Parkinson s Disease His Groundbreaking Research Focuses On Finding Innovative Treatments That Can Slow Down Or Even Halt The Progression Of This Debilitating Neurodegenerative Disorder Isacson s Work Involves Understanding The Underlying Mechanisms Of Parkinson s Disease And Identifying Potential Targets For Therapeutic Interventions By Studying The Pathology Of The Disease And Its Impact On Brain Cells

He Aims To Discover Novel Approaches To Prevent The Loss Of Dopamine producing Neurons

Which Is A Hallmark Of Parkinson s One Of Isacson s Notable Contributions Is In The Field Of Stem Cell Therapy He Has Been At The Forefront Of Utilizing Induced Pluripotent Stem Cells iPSCs To Generate Dopamine producing Neurons In The Laboratory This Breakthrough Technique Holds Immense Promise For Developing Patient specific Cell Replacement Therapies

Providing A Potential Cure For Parkinson s In A

Chapters in this video

0:05

Introduction

0:19

What is Parkinson's disease?

1:44

Currently available therapies

4:14

Current strategies towards the development of new therapies

7:29

Isacson lab: finding genetic determinants of Parkinson's disease

9:37

Why is translation of scientific findings to new therapies so slow?

14:13

Academic research and translational medicine: friends or foes?

16:20

Perspective on future research directions

18:31

Genetic and idiopathic diseases: Parkinson's and Huntington's

20:07

What would you do if you were starting your post-doc now?

23:23

References

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